『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=353326EID:353326, Map:0, LastModified:2019年8月19日(月) 18:33:21, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[杉本 真弓], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Norio Kamenura (日) (読)
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学籍番号 (推奨):
[継承]
2.杉本 真弓 ([徳島大学.病院.診療科.小児·周産·女性科.小児科])
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貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Norimasa Tamehiro (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Reiko Adachi (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
5.友成 さゆり ([徳島大学.技術支援部.常三島技術部門])
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学籍番号 (推奨):
[継承]
6.渡辺 崇人 ([徳島大学.バイオイノベーション研究所])
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学籍番号 (推奨):
[継承]
7.三戸 太郎 ([徳島大学.バイオイノベーション研究所]/[徳島大学.生物資源産業学部.生物資源産業学科.生物生産システム講座])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy  (日)    [継承]
副題 (任意):
要約 (任意): (英) Food scarcity is a serious problem for many developing as well as developed countries. Edible insects have attracted attention recently as a novel food source. Crickets are especially high in nutritional value and easy to breed and harvest. In this study, we evaluated the risk of allergic reactions associated with cricket consumption in individuals with crustacean allergy. We evaluated food allergy risk in the consumption of Gryllus bimaculatus (cricket) in patients with shrimp allergy, using enzyme-linked immunosorbent assay (ELISA) and IgE crosslinking-induced luciferase expression assay (EXiLE). Sera from individuals with shrimp allergy (positive for shrimp-specific IgE by ImmunoCAP (>0.35 UA/mL; n = 9) or without shrimp allergy (negative for shrimp-specific IgE; n = 6) were obtained. There was a strong correlation between shrimp- and Gryllus-specific IgE levels obtained by ELISA (r = 0.99; P < 0.001). The binding of shrimp-specific IgE on shrimp allergen was dose-dependently inhibited by Gryllus allergen (0-1.0 mg/mL). There was a strong correlation between shrimp- and Gryllus-specific IgE responses, as assessed by EXiLE assays (r = 0.89; P < 0.001). We determined that a protein of approximately 40 kDa reacted with the positive, but not negative, sera for shrimp-specific IgE by ImmunoCAP. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis identified the major allergen in shrimp and Gryllus to be tropomyosin. Our data suggest that the cricket allergen has the potential to induce an allergic reaction in individuals with crustacean allergy. Therefore, allergy risk and shrimp-specific IgE levels should be considered before consumption of cricket meal.  (日)    [継承]
キーワード (推奨): 1. (英) Adolescent (日) (読) [継承]
2. (英) Adult (日) (読) [継承]
3. (英) Allergens (日) (読) [継承]
4. (英) Animals (日) (読) [継承]
5. (英) Child (日) (読) [継承]
6. (英) Child, Preschool (日) (読) [継承]
7. (英) Cross Reactions (日) (読) [継承]
8. (英) Female (日) (読) [継承]
9. (英) Gryllidae (日) (読) [継承]
10. (英) Humans (日) (読) [継承]
11. (英) Immunoglobulin E (日) (読) [継承]
12. (英) Male (日) (読) [継承]
13. (英) Shellfish (日) (読) [継承]
14. (英) Shellfish Hypersensitivity (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Molecular Immunology ([Elsevier Science])
(pISSN: 0161-5890, eISSN: 1872-9142)

ISSN (任意): 1872-9142
ISSN: 0161-5890 (pISSN: 0161-5890, eISSN: 1872-9142)
Title: Molecular immunology
Title(ISO): Mol Immunol
Publisher: Elsevier Ltd.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 127 134 [継承]
都市 (任意):
年月日 (必須): 西暦 2019年 2月 初日 (平成 31年 2月 初日) [継承]
URL (任意):
DOI (任意): 10.1016/j.molimm.2018.12.015    (→Scopusで検索) [継承]
PMID (任意): 30597474    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: S0161-5890(18)30629-1  (日)    [継承]
2.(英) Article.ELocationID: 10.1016/j.molimm.2018.12.015  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Clinical Trial  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
5.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]
6.(英) KeywordList.Keyword: Allergy  (日)    [継承]
7.(英) KeywordList.Keyword: Cricket meal  (日)    [継承]
8.(英) KeywordList.Keyword: Edible insect  (日)    [継承]
9.(英) KeywordList.Keyword: Tropomyosin  (日)    [継承]

標準的な表示

和文冊子 ● Kamenura Norio, Mayumi Sugimoto, Tamehiro Norimasa, Adachi Reiko, Sayuri Tomonari, Takahito Watanabe and Taro Mito : Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy, Molecular Immunology, Vol.106, 127-134, 2019.
欧文冊子 ● Kamenura Norio, Mayumi Sugimoto, Tamehiro Norimasa, Adachi Reiko, Sayuri Tomonari, Takahito Watanabe and Taro Mito : Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy, Molecular Immunology, Vol.106, 127-134, 2019.

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