『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1.髙士 祐一
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2. (英) Ishizu Masashi (日) 石津 将 (読) いしづ まさし
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学籍番号 (推奨): **** [ユーザ]
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3.森 博康 ([徳島大学.先端酵素学研究所.基幹研究部門])
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4. (英) Miyashita Kazuyuki (日) (読)
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5. (英) Sakamoto Fumie (日) (読)
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6. (英) Katakami Naoto (日) (読)
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7. (英) Matsuoka Taka-Aki (日) (読)
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8. (英) Yasuda Tetsuyuki (日) (読)
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9.橋田 誠一 ([宮崎医科大学])
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10.松久 宗英 ([徳島大学.先端酵素学研究所.基幹研究部門]/徳島大学病院アンチエイジングセンター センター長(併任))
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11.黒田 暁生 ([徳島大学.先端酵素学研究所.基幹研究部門])
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題名 (必須): (英) Circulating osteocalcin as a bone-derived hormone is inversely correlated with body fat in patients with type 1 diabetes.  (日)    [継承]
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要約 (任意): (英) The objective of the present study was to investigate the correlations between serum undercarboxylated osteocalcin (ucOC) or osteocalcin (OC) concentrations and %body fat, serum adiponectin and free-testosterone concentration, muscle strength and dose of exogenous insulin in patients with type 1 diabetes. We recruited 73 Japanese young adult patients with childhood-onset type 1 diabetes. All participants were receiving insulin replacement therapy. The correlations between logarithmic serum ucOC or OC concentrations and each parameter were examined. Serum ucOC and OC concentrations were inversely correlated with %body fat (r = -0.319, P = 0.007; r = -0.321, P = 0.006, respectively). Furthermore, multiple linear regression analyses were performed to determine whether or not serum ucOC or OC concentrations were factors associated with %body fat. Serum ucOC and OC concentrations remained significant factors even after adjusting for gender, HbA1c, body weight-adjusted total daily dose of insulin and duration of diabetes (β = -0.260, P = 0.027; β = -0.254, P = 0.031, respectively). However, serum ucOC and OC concentrations were not correlated with serum adiponectin or free-testosterone concentrations, muscle strength or dose of exogenous insulin. In conclusion, our study demonstrates the inverse correlation between serum ucOC or OC concentrations and body fat in patients with type 1 diabetes.  (日)    [継承]
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誌名 (必須): PLoS ONE (Public Library of Science)
(eISSN: 1932-6203)

ISSN (任意): 1932-6203
ISSN: 1932-6203 (eISSN: 1932-6203)
Title: PloS one
Title(ISO): PLoS One
Publisher: Public Library of Science
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 14 [継承]
(必須): 5 [継承]
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年月日 (必須): 西暦 2019年 5月 3日 (令和 元年 5月 3日) [継承]
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DOI (任意): 10.1371/journal.pone.0216416    (→Scopusで検索) [継承]
PMID (任意): 31050684    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Yuichi Takashi, Masashi Ishizu, Hiroyasu Mori, Kazuyuki Miyashita, Fumie Sakamoto, Naoto Katakami, Taka-Aki Matsuoka, Tetsuyuki Yasuda, Seiichi Hashida, Munehide Matsuhisa and Akio Kuroda : Circulating osteocalcin as a bone-derived hormone is inversely correlated with body fat in patients with type 1 diabetes., PLoS ONE, Vol.14, No.5, 2019.
欧文冊子 ● Yuichi Takashi, Masashi Ishizu, Hiroyasu Mori, Kazuyuki Miyashita, Fumie Sakamoto, Naoto Katakami, Taka-Aki Matsuoka, Tetsuyuki Yasuda, Seiichi Hashida, Munehide Matsuhisa and Akio Kuroda : Circulating osteocalcin as a bone-derived hormone is inversely correlated with body fat in patients with type 1 diabetes., PLoS ONE, Vol.14, No.5, 2019.

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