| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Zhang Youzuo (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 2. | (英) Kouguchi Tomomi (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 3. | (英) Shimizu Kazuo (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 4. | (英) Sato Mikako (日) (読)
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| ○貢献度 (任意): |
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| 5. | (英) Takahata Yoshihisa (日) (読)
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| 6. | 森松 文毅 ([徳島大学.研究支援・産官学連携センター])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| ○題名 (必須): | □ | (英) Chicken collagen hydrolysate reduces proinflammatory cytokine production in C57BL/6.KOR-ApoEshl mice. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Effects of chicken collagen hydrolysate (CCH) on atherogenesis in apolipoprotein E-deficient C57BL/6.KOR-ApoE(shl) mice were investigated in this paper. The mice were fed on either a normal CE-2 diet (control group) or a diet containing 10% CCH (CCH group) for 12 wk. Compared with that of the control, the amount of total plasma cholesterol, total hepatic cholesterol and hepatic triglycerides in the CCH group was reduced by 14.4, 24.7 and 42.8%, respectively. Histological analysis results showed that the abundance of diffuse hepatic lipid droplets and fat vacuoles was decreased in the CCH group. Meanwhile, the concentration of proinflammatory cytokines in the CCH group plasma, including interleukin-6 (IL-6), soluble intercellular adhesion molecule-1 (sICAM-1), and tumor necrosis factor-alpha (TNF-alpha), was downregulated by 43.4, 17.9 and 24.1%, respectively. The present results suggested that CCH treatment might help prevent atherosclerosis through not only its lipid-lowering effects but also inhibiting expression of inflammatory cytokines. (日)
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| ○キーワード (推奨): | 1. | (英) Animals (日) (読)
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| 2. | (英) Apolipoproteins E (日) (読)
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| 3. | 動脈硬化 (atherosclerosis)
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| 4. | (英) Chickens (日) (読)
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| 5. | コラーゲン (collagen)
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| 6. | (英) Cytokines (日) (読)
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| 7. | (英) Cytoplasmic Vesicles (日) (読)
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| 8. | (英) Dietary Proteins (日) (読)
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| 9. | (英) Down-Regulation (日) (読)
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| 10. | (英) Fatty Liver (日) (読)
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| 11. | (英) Intercellular Adhesion Molecule-1 (日) (読)
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| 12. | (英) Interleukin-6 (日) (読)
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| 13. | (英) Lipids (日) (読)
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| 14. | (英) Liver (日) (読)
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| 15. | (英) Male (日) (読)
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| 16. | (英) Mice (日) (読)
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| 17. | (英) Mice, Inbred C57BL (日) (読)
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| 18. | (英) Mice, Transgenic (日) (読)
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| 19. | (英) Protein Hydrolysates (日) (読)
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| 20. | (英) Random Allocation (日) (読)
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| 21. | (英) Tumor Necrosis Factor-alpha (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Journal of Nutritional Science and Vitaminology ([日本栄養·食糧学会]/[日本ビタミン学会])
(pISSN: 0301-4800, eISSN: 1881-7742)
| ○ISSN (任意): | □ | 1881-7742
ISSN: 0301-4800
(pISSN: 0301-4800, eISSN: 1881-7742) Title: Journal of nutritional science and vitaminologyTitle(ISO): J Nutr Sci Vitaminol (Tokyo)Supplier: 日本ビタミン学会Publisher: Center for Academic Publications Japan (NLM Catalog)
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| ○巻 (必須): | □ | 56
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| ○号 (必須): | □ | 3
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| ○頁 (必須): | □ | 208 210
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2010年 3月 初日 (平成 22年 3月 初日)
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| ○URL (任意): |
| ○DOI (任意): |
| ○PMID (任意): | □ | 20651463 (→Scopusで検索)
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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