『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=338005EID:338005, Map:0, LastModified:2019年8月19日(月) 18:48:57, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[岸 誠司], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨):
カテゴリ (推奨):
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学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.岸 史
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学籍番号 (推奨): **** [ユーザ]
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2.長井 幸二郎
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3.高松 典通 ([徳島大学.病院.診療支援部])
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4.冨永 辰也 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.医用検査学系.生体機能解析学])
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5.田蒔 昌憲 ([徳島大学.病院.先端医科医療開発研究プロジェクト]/[徳島大学.病院.中央診療施設等.検査部]/[徳島大学.病院.診療科.内科.腎臓内科])
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6. (英) Shibata E. (日) 柴田 恵理子 (読)
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7.村上 太一
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8.岸 誠司
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9.安部 秀斉
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10. (英) Koezuka Y (日) (読)
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11. (英) Minagawa N (日) (読)
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12. (英) Ichien G (日) (読)
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13.土井 俊夫
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題名 (必須): (英) Urinary type IV collagen excretion is involved in the decline in estimated glomerular filtration rate in the Japanese general population without diabetes: A 5-year observational study.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Urinary type IV collagen (U-Col4) and albumin excretion is evaluated to monitor the development of diabetic kidney disease. However, U-Col4 excretion in the general population without diabetes has not yet been fully elucidated. In this study, 1067 participants without diabetes and with urinary albumin-creatinine ratio <300 mg/gCr (normo- or microalbuminuria) who underwent an annual health examination in 2004 were enrolled and observed for 5 years. They were divided according to the amount of U-Col4 or urinary albumin excreted. The decline in estimated glomerular filtration rate (eGFR) was calculated. In participants with eGFR ≥80 mL/min, abnormal U-Col4 excretion was indicated as a significant independent risk factor for 10% eGFR change per year, which is one of the prognostic factors for the development of end-stage kidney disease. Moreover, in contrast to urinary albumin excretion, U-Col4 excretion was not related to age or kidney function, suggesting that some individuals with abnormal U-Col4 excretion can have an independent hidden risk for the development of kidney dysfunction. In conclusion, it is important to measure U-Col4 excretion in the general population without diabetes to determine changes in renal features in every individual and help detect future complications such as diabetic kidney disease. If U-Col4 excretion is abnormal, kidney manifestation should be carefully followed up, even if the kidney function and urinalysis findings are normal.  (日)    [継承]
キーワード (推奨): 1. (英) Adult (日) (読) [継承]
2. (英) Aged (日) (読) [継承]
3. (英) Aged, 80 and over (日) (読) [継承]
4. (英) Albuminuria (日) (読) [継承]
5. (英) Asian Continental Ancestry Group (日) (読) [継承]
6. (英) Collagen Type IV (日) (読) [継承]
7. (英) Diabetic Nephropathies (日) (読) [継承]
8. (英) Disease Progression (日) (読) [継承]
9. (英) Female (日) (読) [継承]
10. (英) Glomerular Filtration Rate (日) (読) [継承]
11. (英) Humans (日) (読) [継承]
12. (英) Japan (日) (読) [継承]
13. (英) Kaplan-Meier Estimate (日) (読) [継承]
14. (英) Male (日) (読) [継承]
15. (英) Middle Aged (日) (読) [継承]
16. (英) Prognosis (日) (読) [継承]
17. (英) Renal Insufficiency (日) (読) [継承]
18. (英) Risk Factors (日) (読) [継承]
19. (英) Young Adult (日) (読) [継承]
発行所 (推奨):
誌名 (必須): PLoS ONE (Public Library of Science)
(eISSN: 1932-6203)

ISSN (任意): 1932-6203
ISSN: 1932-6203 (eISSN: 1932-6203)
Title: PloS one
Title(ISO): PLoS One
Publisher: PLOS
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 13 [継承]
(必須): 4 [継承]
(必須): e0195523 e0195523 [継承]
都市 (任意):
年月日 (必須): 西暦 2018年 4月 6日 (平成 30年 4月 6日) [継承]
URL (任意):
DOI (任意): 10.1371/journal.pone.0195523    (→Scopusで検索) [継承]
PMID (任意): 29624611    (→Scopusで検索) [継承]
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機関リポジトリ : 112361 [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1371/journal.pone.0195523  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Observational Study  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Fumi Kishi, Kojiro Nagai, Norimichi Takamatsu, Tatsuya Tominaga, Masanori Tamaki, E. Shibata, Taichi Murakami, Seiji Kishi, Hideharu Abe, Y Koezuka, N Minagawa, G Ichien and Toshio Doi : Urinary type IV collagen excretion is involved in the decline in estimated glomerular filtration rate in the Japanese general population without diabetes: A 5-year observational study., PLoS ONE, Vol.13, No.4, e0195523, 2018.
欧文冊子 ● Fumi Kishi, Kojiro Nagai, Norimichi Takamatsu, Tatsuya Tominaga, Masanori Tamaki, E. Shibata, Taichi Murakami, Seiji Kishi, Hideharu Abe, Y Koezuka, N Minagawa, G Ichien and Toshio Doi : Urinary type IV collagen excretion is involved in the decline in estimated glomerular filtration rate in the Japanese general population without diabetes: A 5-year observational study., PLoS ONE, Vol.13, No.4, e0195523, 2018.

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