『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=326882)

EID=326882EID:326882, Map:0, LastModified:2019年3月2日(土) 20:40:07, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[細川 義隆], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.細川 義隆 ([徳島大学.病院.診療科.歯科.むし歯科(第一保存科)])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.細川 育子 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.歯科保存学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Shindo Satoru (日) 進藤 智 (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.尾崎 和美 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.口腔保健学系.口腔保健支援学]/[徳島大学.歯学部.口腔保健学科.口腔保健支援学講座])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5.松尾 敬志
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) IL-29 Enhances CXCL10 Production in TNF--stimulated Human Oral Epithelial Cells.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family. It was recently detected in the gingival crevicular fluid of periodontitis patients. However, the role of IL-29 in the pathogenesis of periodontal disease remains unknown. The aim of this study was to examine the effects of IL-29 on C-X-C motif chemokine ligand 10 (CXCL10) production in human oral epithelial cells. We measured CXCL10 production in TR146 cells, which is a human oral epithelial cell line, using an enzyme-linked immunosorbent assay. We used a Western blot analysis to detect IL-29 receptor expression and the phosphorylation levels of signal transduction molecules, including p38 mitogen-activated protein kinases (MAPK), signal transducer and activator of transcription 3 (STAT3), and nuclear factor (NF)- B p65, in the TR146 cells. The TR146 cells expressed the IL-29 receptor. IL-29 induced CXCL10 production in the TR146 cells. IL-29 significantly enhanced CXCL10 production in tumor necrosis factor (TNF)--stimulated TR146 cells. The p38 MAPK, STAT3, and NF-B pathways were found to be related to the IL-29-induced enhancement of CXCL10 production in TNF--stimulated TR146 cells. IL-29 promotes T helper 1-cell accumulation in periodontal lesions by inducing CXCL10 production in oral epithelial cells.  (日)    [継承]
キーワード (推奨):
発行所 (推奨): Taylor & Francis [継承]
誌名 (必須): Immunological Investigations (Informa Healthcare)
(pISSN: 0882-0139, eISSN: 1532-4311)

ISSN (任意): 1532-4311
ISSN: 0882-0139 (pISSN: 0882-0139, eISSN: 1532-4311)
Title: Immunological investigations
Title(ISO): Immunol Invest
Publisher: Taylor & Francis
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 46 [継承]
(必須): 6 [継承]
(必須): 615 624 [継承]
都市 (任意):
年月日 (必須): 西暦 2017年 8月 初日 (平成 29年 8月 初日) [継承]
URL (任意):
DOI (任意): 10.1080/08820139.2017.1336176    (→Scopusで検索) [継承]
PMID (任意): 28753407    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
機関リポジトリ : 112817 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo : IL-29 Enhances CXCL10 Production in TNF--stimulated Human Oral Epithelial Cells., Immunological Investigations, Vol.46, No.6, 615-624, 2017.
欧文冊子 ● Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki and Takashi Matsuo : IL-29 Enhances CXCL10 Production in TNF--stimulated Human Oral Epithelial Cells., Immunological Investigations, Vol.46, No.6, 615-624, 2017.

関連情報

Number of session users = 0, LA = 2.72, Max(EID) = 372616, Max(EOID) = 996877.