『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=325422EID:325422, Map:0, LastModified:2017年10月18日(水) 13:41:15, Operator:[三好 小文], Avail:TRUE, Censor:0, Owner:[山田 久嗣], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1. (英) Kondo Teruyuki (日) (読)
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2. (英) Kimura Yu (日) (読)
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3.山田 久嗣 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.応用生命系.応用生物資源学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.応用生命講座])
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4. (英) Aoyama Yasuhiro (日) (読)
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題名 (必須): (英) Polymeric (1) H MRI Probes for Visualizing Tumor In Vivo.  (日)    [継承]
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要約 (任意): (英) Magnetic resonance imaging (MRI) has become a prominent non- or low-invasive imaging technique, providing high-resolution, three-dimensional images as well as physiological information about tissues. Low-molecular-weight Gd-MRI contrast agents (CAs), such as Gd-DTPA (DTPA: diethylenetriaminepentaacetic acid), are commonly used in the clinical diagnosis, while macromolecular Gd-MRI CAs have several advantages over low-molecular-weight Gd-MRI CAs, which help minimize the dose of CAs and the risk of side effects. Accordingly, we developed chiral dendrimer Gd-MRI CAs, which showed high r1 values. The association constant values (Ka ) of S-isomeric dendrimer CAs to bovine serum albumin (BSA) were higher than those of R-isomeric dendrimer CAs. Besides, based on a totally new concept, we developed (13) C/(15) N-enriched multiple-resonance NMR/MRI probes, which realized highly selective observation of the probes and analysis of metabolic reactions of interest. This account summarizes our recent study on developing both chiral dendrimer Gd-MRI CAs, and self-traceable (13) C/(15) N-enriched phosphorylcholine polymer probes for early detection of tumors.  (日)    [継承]
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誌名 (必須): Chemical Record ([社団法人 日本化学会])
(pISSN: 1527-8999, eISSN: 1528-0691)

ISSN (任意): 1528-0691
ISSN: 1527-8999 (pISSN: 1527-8999, eISSN: 1528-0691)
Title: Chemical record (New York, N.Y.)
Title(ISO): Chem Rec
Supplier: The Chemical Society of Japan
Publisher: Wiley Publishing
 (NLM Catalog  (Wiley  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 555 568 [継承]
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年月日 (必須): 西暦 2017年 7月 初日 (平成 29年 7月 初日) [継承]
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DOI (任意): 10.1002/tcr.201600144    (→Scopusで検索) [継承]
PMID (任意): 28387472    (→Scopusで検索) [継承]
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標準的な表示

和文冊子 ● Teruyuki Kondo, Yu Kimura, Hisatsugu Yamada and Yasuhiro Aoyama : Polymeric (1) H MRI Probes for Visualizing Tumor In Vivo., Chemical Record, Vol.17, No.6, 555-568, 2017.
欧文冊子 ● Teruyuki Kondo, Yu Kimura, Hisatsugu Yamada and Yasuhiro Aoyama : Polymeric (1) H MRI Probes for Visualizing Tumor In Vivo., Chemical Record, Vol.17, No.6, 555-568, 2017.

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