『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=319395)

EID=319395EID:319395, Map:0, LastModified:2016年8月28日(日) 21:57:56, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[堤 理恵], Read:継承, Write:継承, Delete:継承.
種別 (必須):
言語 (必須): 英語 [継承]
招待 (推奨):
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カテゴリ (推奨):
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組織 (推奨):
著者 (必須): 1. (英) Venkatesh Thejaswini (日) (読)
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2. (英) Suresh S. Padmanaban (日) (読)
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3.堤 理恵 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.代謝栄養学])
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学籍番号 (推奨):
[継承]
題名 (必須): (英) Non-coding RNAs: Functions and applications in endocrine-related cancer.  (日)    [継承]
副題 (任意):
要約 (任意): (英) A significant fraction of the human genome is transcribed as non-coding RNAs (ncRNAs). This non-coding transcriptome has challenged the notion of the central dogma and its involvement in transcriptional and post-transcriptional regulation of gene expression is well established. Interestingly, several ncRNAs are dysregulated in cancer and current non-coding transcriptome research aims to use our increasing knowledge of these ncRNAs for the development of cancer biomarkers and anti-cancer drugs. In endocrine-related cancers, for which survival rates can be relatively low, there is a need for such advancements. In this review, we aimed to summarize the roles and clinical implications of recently discovered ncRNAs, including long ncRNAs, PIWI-interacting RNAs, tRNA- and Y RNA-derived ncRNAs, and small nucleolar RNAs, in endocrine-related cancers affecting both sexes. We focus on recent studies highlighting discoveries in ncRNA biology and expression in cancer, and conclude with a discussion on the challenges and future directions, including clinical application. ncRNAs show great promise as diagnostic tools and therapeutic targets, but further work is necessary to realize the potential of these unconventional transcripts.  (日)    [継承]
キーワード (推奨): 1. (英) Biomarkers, Tumor (日) (読) [継承]
2. (英) Endocrine Gland Neoplasms (日) (読) [継承]
3. (英) Female (日) (読) [継承]
4. (英) Gene Expression Regulation (日) (読) [継承]
5. (英) Humans (日) (読) [継承]
6. (英) Male (日) (読) [継承]
7. (英) RNA, Long Noncoding (日) (読) [継承]
8. (英) RNA, Small Interfering (日) (読) [継承]
9. (英) RNA, Small Nucleolar (日) (読) [継承]
10. (英) Transcriptome (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Molecular and Cellular Endocrinology ([Elsevier])
(pISSN: 0303-7207, eISSN: 1872-8057)

ISSN (任意): 1872-8057
ISSN: 0303-7207 (pISSN: 0303-7207, eISSN: 1872-8057)
Title: Molecular and cellular endocrinology
Title(ISO): Mol Cell Endocrinol
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 416 [継承]
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(必須): 88 96 [継承]
都市 (任意):
年月日 (必須): 西暦 2015年 9月 7日 (平成 27年 9月 7日) [継承]
URL (任意):
DOI (任意): 10.1016/j.mce.2015.08.026    (→Scopusで検索) [継承]
PMID (任意): 26360585    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1016/j.mce.2015.08.026  (日)    [継承]
2.(英) Article.ELocationID: S0303-7207(15)30066-6  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Review  (日)    [継承]
5.(英) KeywordList.Keyword: Endocrine-related cancer  (日)    [継承]
6.(英) KeywordList.Keyword: Long non-coding RNA  (日)    [継承]
7.(英) KeywordList.Keyword: Non-coding RNA  (日)    [継承]
8.(英) KeywordList.Keyword: PIWI-interacting RNA  (日)    [継承]
9.(英) KeywordList.Keyword: Small nucleolar RNA  (日)    [継承]
10.(英) KeywordList.Keyword: Y RNA  (日)    [継承]
11.(英) KeywordList.Keyword: tRNA-derived small RNA  (日)    [継承]

標準的な表示

和文冊子 ● (種別) : Thejaswini Venkatesh, Padmanaban S. Suresh and Rie Tsutsumi : Non-coding RNAs: Functions and applications in endocrine-related cancer., Molecular and Cellular Endocrinology, Vol.416, (号), 88-96, (発行所), (都市), Sep. 2015.
欧文冊子 ● (種別) : Thejaswini Venkatesh, Padmanaban S. Suresh and Rie Tsutsumi : Non-coding RNAs: Functions and applications in endocrine-related cancer., Molecular and Cellular Endocrinology, Vol.416, (号), 88-96, (発行所), (都市), Sep. 2015.

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