『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=315230)

EID=315230EID:315230, Map:0, LastModified:2017年1月21日(土) 20:29:27, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[木戸 淳一], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.中島 由紀子 ([徳島大学.病院.診療科.歯科.歯周病科(第二保存科)])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.稲垣 裕司 ([徳島大学.病院.診療科.歯科.歯周病科(第二保存科)])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.木戸 淳一 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.歯周歯内治療学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.永田 俊彦
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Advanced glycation end-products increase expression of S100A8 and A9 via RAGE-MAPK in rat dental pulp cells  (日)    [継承]
副題 (任意):
要約 (任意): (英) Advanced glycation end products (AGE) are involved in the progression of diabetic complications. Although our previous reports show that AGE increased dental pulp calcification, AGE accumulation is also associated with inflammation. This study examined AGE effect on the expression of inflammation factors using rat dental pulp tissues and cell cultures. Receptor for AGE (RAGE), S100A8, S100A9, and interleukin (IL)-1β were selected as inflammation parameters. Rat dental pulp cells were cultured and treated with AGE, and the effects were determined by real-time PCR. An anti-RAGE antibody or MAPK pathway inhibitors (PD98059, SB203580, and SP60012) were used to investigate AGE signaling pathway. The mRNA levels of RAGE, S100A8, S100A9, and IL-1β were higher in diabetic pulp tissues. AGE increased mRNA expressions of S100A8, S100A9, and IL-1β in cultured dental pulp cells. In the presence of anti-RAGE antibody, AGE did not increase in S100A8 or S100A9 expressions. The AGE-induced increases in S100A8 and S100A9 were inhibited by PD98059 and SB203580, respectively. Advanced glycation end products increased mRNA expression of S100A8, S100A9, and IL-1β under diabetic pulp conditions, and AGE-induced increases in S100A8 and S100A9 expressions may be associated with the RAGE-MAPK signaling pathway.  (日)    [継承]
キーワード (推奨): 1. (英) Advanced Glycosylation End Product-Specific Receptor (日) (読) [継承]
2. (英) Animals (日) (読) [継承]
3. (英) Antibodies (日) (読) [継承]
4. (英) Calgranulin A (日) (読) [継承]
5. (英) Calgranulin B (日) (読) [継承]
6. (英) Cells, Cultured (日) (読) [継承]
7. (英) Dental Pulp (日) (読) [継承]
8. (英) Diabetes Mellitus (日) (読) [継承]
9. (英) Flavonoids (日) (読) [継承]
10. (英) Gene Expression (日) (読) [継承]
11. (英) Glycosylation End Products, Advanced (日) (読) [継承]
12. (英) Imidazoles (日) (読) [継承]
13. (英) Interleukin-1beta (日) (読) [継承]
14. (英) MAP Kinase Signaling System (日) (読) [継承]
15. (英) Male (日) (読) [継承]
16. (英) Mitogen-Activated Protein Kinases (日) (読) [継承]
17. (英) Pyridines (日) (読) [継承]
18. (英) RNA, Messenger (日) (読) [継承]
19. (英) Rats (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Oral Diseases (Munksgaard)
(pISSN: 1354-523X, eISSN: 1601-0825)

ISSN (任意): 1601-0825
ISSN: 1354-523X (pISSN: 1354-523X, eISSN: 1601-0825)
Title: Oral diseases
Title(ISO): Oral Dis
Publisher: Blackwell
 (NLM Catalog  (Wiley  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 21 [継承]
(必須): 3 [継承]
(必須): 328 334 [継承]
都市 (任意):
年月日 (必須): 西暦 2015年 0月 初日 (平成 27年 0月 初日) [継承]
URL (任意):
DOI (任意): 10.1111/odi.12280    (→Scopusで検索) [継承]
PMID (任意): 25098709    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000351635600008 [継承]
Scopus (任意): 2-s2.0-84925124937 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.ELocationID: 10.1111/odi.12280  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]
4.(英) KeywordList.Keyword: RAGE-MAPK signaling  (日)    [継承]
5.(英) KeywordList.Keyword: S100A8  (日)    [継承]
6.(英) KeywordList.Keyword: S100A9  (日)    [継承]
7.(英) KeywordList.Keyword: advanced glycation end products  (日)    [継承]
8.(英) KeywordList.Keyword: dental pulp  (日)    [継承]
9.(英) KeywordList.Keyword: diabetes  (日)    [継承]

標準的な表示

和文冊子 ● Yukiko Nakajima, Yuji Inagaki, Jun-ichi Kido and Toshihiko Nagata : Advanced glycation end-products increase expression of S100A8 and A9 via RAGE-MAPK in rat dental pulp cells, Oral Diseases, Vol.21, No.3, 328-334, 2015.
欧文冊子 ● Yukiko Nakajima, Yuji Inagaki, Jun-ichi Kido and Toshihiko Nagata : Advanced glycation end-products increase expression of S100A8 and A9 via RAGE-MAPK in rat dental pulp cells, Oral Diseases, Vol.21, No.3, 328-334, 2015.

関連情報

Number of session users = 0, LA = 0.99, Max(EID) = 382766, Max(EOID) = 1022356.