| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○著者 (必須): | 1. | (英) C Jha Subash (日) (読)
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| 2. | 東野 恒作
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| 3. | 酒井 紀典 ([徳島大学.病院.中央診療施設等.高度先進整形外科診療部])
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| 4. | 髙田 洋一郎
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| 5. | 阿部 光伸
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| 6. | (英) Yamashita Kazuta (日) (読)
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| 7. | (英) Morimoto Masatoshi (日) (読)
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| 8. | 福田 昇司
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| 9. | 長町 顕弘
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| 10. | 西良 浩一 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.運動機能外科学])
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| ○題名 (必須): | □ | (英) Clinical Significance of High-intensity Zone for Discogenic Low Back Pain: A Review. (日)
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| ○要約 (任意): | □ | (英) High-intensity zone (HIZ) was originally described as a high-intensity signal on T2-weighted magnetic resonance (MR) images, located in the posterior annulus fibrosus, clearly separated from the nucleus pulposus. Among symptomatic patients with low back pain, HIZ is present in 28-59% of cases. In morphologically abnormal discs, high sensitivity and specificity of 81% and 79%, respectively, were reported for HIZs and concordant pain during discography. In contrast, another report indicated low rates. Although most papers reported high sensitivity and specificity for this relationship, it remains controversial. Regarding the pathology of HIZs, inflammatory granulation tissues are found at sites showing HIZs. Such inflammatory tissues produce pro-inflammatory cytokines and mediators, which sensitize the nociceptors within the disc and cause pain. An effective treatment for this condition is yet to be established. Recently, minimally invasive surgery using percutaneous endoscopic discectomy (PED) under local anesthesia was introduced. After removal of the degenerated disc material, the HIZ is identified with the endoscope and then coagulated and modulated with a bipolar radio pulse. This technique is called thermal annuloplasty. In conclusion, HIZs is an important sign of painful intervertebral disc disruption, if identified precisely based on factors such as location and intensity. J. Med. Invest. 63: 1-7, February, 2016. (日)
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| ○キーワード (推奨): |
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| ○誌名 (必須): | □ | The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
| ○ISSN (任意): | □ | 1349-6867
ISSN: 1343-1420
(pISSN: 1343-1420, eISSN: 1349-6867) Title: The journal of medical investigation : JMITitle(ISO): J Med InvestSupplier: 徳島大学Publisher: University of Tokushima (NLM Catalog)
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(Scopus)
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| ○巻 (必須): | □ | 63
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| ○号 (必須): | □ | 1-2
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| ○頁 (必須): | □ | 1 7
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| ○年月日 (必須): | □ | 西暦 2016年 0月 初日 (平成 28年 0月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.2152/jmi.63.1 (→Scopusで検索)
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| ○PMID (任意): | □ | 27040045 (→Scopusで検索)
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| ○Scopus (任意): | □ | 2-s2.0-84962178586
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| ○機関リポジトリ : | □ | 111145
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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