| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○著者 (必須): | 1. | 楠瀬 賢也
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| 2. | (英) Sato M (日) (読)
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| 3. | 山田 博胤 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域循環器内科学])
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| 4. | (英) Saijo Y (日) (読)
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| 5. | 坂東 美佳
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| 6. | (英) Hirata Y (日) (読)
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| 7. | (英) Nishio S (日) (読)
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| 8. | (英) Hayashi S (日) (読)
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| 9. | 佐田 政隆 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.循環器内科学])
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| ○題名 (必須): | □ | (英) Prognostic implications of non-invasive vascular function tests in high-risk atherosclerosis patients. (日)
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| ○要約 (任意): | □ | (英) BACKGROUND: The aim of this study was to assess the role of clinically available vascular function tests as predictors of cardiovascular events and decline in kidney function.MethodsandResults:One hundred and fourteen patients who had at least 2 cardiovascular risk factors were recruited for vascular function assessment including ankle-brachial blood pressure index (ABI), brachial-ankle pulse wave velocity (baPWV), cardio-ankle vascular index (CAVI) and flow-mediated vasodilatation (%FMD). During a median period of 51 months, 35 patients reached the primary endpoint (29 cardiovascular events and 6 cardiac deaths), and 30 patients reached the secondary endpoint (decline in kidney function: defined as a 5% per year decline of estimated glomerular filtration rate). In sequential Cox models, a model on the basis of the Framingham risk score, hemoglobin, and high-sensitivity C-reactive protein (chi-squared, 16.6) was improved by the ABI (chi-squared: 21.5; P=0.047). The baPWV (hazard ratio: 1.42 per 1 SD increase; P=0.025) and the CAVI (hazard ratio: 1.52 per 1 SD increase; P=0.040) were associated with the secondary endpoint. The %FMD was only slightly associated with the primary and secondary endpoints.CONCLUSIONS: Both ABI and baPWV are significantly associated with future cardiovascular events in high-risk patients with cardiovascular disease. The predictive capabilities of these parameters are greater than that of other parameters in this cohort. (日)
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| ○キーワード (推奨): | 1. | (英) Cardiovascular event (日) (読)
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| 2. | (英) Endothelial function (日) (読)
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| 3. | (英) Kidney function (日) (読)
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| 4. | (英) Vascular function (日) (読)
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| ○発行所 (推奨): | □ | 社団法人 日本循環器学会
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| ○誌名 (必須): | □ | Circulation Journal ([社団法人 日本循環器学会])
(pISSN: 1346-9843, eISSN: 1347-4820)
| ○ISSN (任意): | □ | 1347-4820
ISSN: 1346-9843
(pISSN: 1346-9843, eISSN: 1347-4820) Title: Circulation journal : official journal of the Japanese Circulation SocietyTitle(ISO): Circ JSupplier: 社団法人日本循環器学会Publisher: Japanese Circulation Society (NLM Catalog)
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| ○巻 (必須): | □ | 80
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| ○号 (必須): | □ | 4
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| ○頁 (必須): | □ | 1034 1040
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| ○年月日 (必須): | □ | 西暦 2016年 3月 25日 (平成 28年 3月 25日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1253/circj.CJ-15-1356 (→Scopusで検索)
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| ○PMID (任意): | □ | 26936237 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): | □ | 000373401900036
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| ○Scopus (任意): | □ | 2-s2.0-84961625684
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| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.1253/circj.CJ-15-1356 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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