○種別 (必須): | □ | 学術論文 (審査論文)
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○言語 (必須): | □ | 英語
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○招待 (推奨): |
○審査 (推奨): |
○カテゴリ (推奨): | □ | 研究
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○共著種別 (推奨): | □ | 徳島大学以外での研究機関内共著 (徳島大学以外での研究機関内での共同研究)
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○学究種別 (推奨): |
○組織 (推奨): |
○著者 (必須): | 1. | (英) Ahmad Masud (日) (読)
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| 2. | (英) Iseki Hachiro (日) (読)
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| 3. | (英) Abduweli Dawud (日) (読)
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| 4. | 馬場 麻人 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔顎顔面形態学])
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| 5. | (英) Tabata Makoto J (日) (読)
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| 6. | (英) Takano Yoshiro (日) (読)
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○題名 (必須): | □ | (英) Ultrastructural and histochemical evaluation of appositional mineralization of circumpulpal dentin at the crown- and root-analog portions of rat incisors. (日)
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○要約 (任意): | □ | (英) (日) Mineralization of circumpulpal dentin has been interpreted in such a way that predentin matrix is abruptly converted to almost fully mineralized dentin at the mineralization front. A group of investigators pointed out the existence of intermediary layer along the mineralization front of rat incisor dentin and claimed that dentin mineralization is a rather transient process. Owing to a paucity of information, however, the entity of transient mineralization of dentin has remained elusive. Here we confirmed the existence of a lightly mineralized layer (LL) along the mineralization front of rat incisor dentin, recognizable by both light and electron microscopy, in routinely processed specimens. LL less than 3 µm thick was shown to be located along the mineralization front of crown-analog dentin and tapered out toward the root analog of the incisor. Electron microscopy revealed that mineral deposition first occurred in the non-collagenous matrix of LL and that mineralization of collagen fibers took place sometime later at the conventional mineralization front. Microscopic appearance of the mineral phase of LL varied considerably depending on the histological processing of ultrathin sections, thus explaining the inconsistent interpretation of dentin mineralization in previous studies. These data suggest that mineralization of circumpulpal dentin in rat incisors proceeds in a stepwise or a transient manner, initiated by crystal deposition in the non-collagenous matrix followed by massive mineral deposition in collagen fibers at the mineralization front. The thickness of LL where only the non-collagenous matrix is mineralized may vary in relation to differences in the local non-collagenous matrix and also the rate of collagen mineralization in the respective portions of circumpulpal dentin.
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○キーワード (推奨): | 1. | (英) Animals (日) (読)
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| 2. | (英) Calcification, Physiologic (日) (読)
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| 3. | コラーゲン (collagen)
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| 4. | (英) Dental Restoration, Permanent (日) (読)
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| 5. | (英) Dentin (日) (読)
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| 6. | (英) Histocytochemistry (日) (読)
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| 7. | (英) Incisor (日) (読)
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| 8. | 透過電子顕微鏡法 (transmission electron microscopy)
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| 9. | (英) Rats (日) (読)
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| 10. | (英) Rats, Sprague-Dawley (日) (読)
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| 11. | (英) Rats, Wistar (日) (読)
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| 12. | (英) Tooth Root (日) (読)
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○発行所 (推奨): |
○誌名 (必須): | □ | Journal of Electron Microscopy (日本顕微鏡学会)
(pISSN: 0022-0744, eISSN: 1477-9986)
○ISSN (任意): | □ | 1477-9986
ISSN: 0022-0744
(pISSN: 0022-0744, eISSN: 1477-9986) Title: Journal of electron microscopyTitle(ISO): J Electron Microsc (Tokyo)Supplier: Oxford University PressPublisher: Oxford University Press (NLM Catalog)
(IEEE)
(医中誌Web)
(Scopus)
(CrossRef)
(Scopus information is found. [need login])
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○巻 (必須): | □ | 60
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○号 (必須): | □ | 1
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○頁 (必須): | □ | 79 87
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○都市 (任意): |
○年月日 (必須): | □ | 西暦 2010年 10月 28日 (平成 22年 10月 28日)
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○URL (任意): |
○DOI (任意): | □ | 10.1093/jmicro/dfq075 (→Scopusで検索)
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○PMID (任意): | □ | 21030417 (→Scopusで検索)
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○備考 (任意): | 1. | (英) PublicationType: Evaluation Studies (日)
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| 2. | (英) PublicationType: Journal Article (日)
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| 3. | (英) PublicationType: Research Support, Non-U.S. Gov't (日)
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