『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=304089EID:304089, Map:0, LastModified:2016年4月19日(火) 19:04:39, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[松井 尚子], Read:継承, Write:継承, Delete:継承.
種別 (必須): 総説·解説 [継承]
言語 (必須): 日本語 [継承]
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著者 (必須): 1.松井 尚子 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.社会医学系.医療教育学])
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[継承]
題名 (必須): (英) Multifocal motor neuropathy: Current review of epidemiology and treatment  (日) 多巣性運動ニューロパチー:疫学と治療の実態   [継承]
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要約 (任意): (英) The diagnosis of multifocal motor neuropathy (MMN) is often missed because MMN disguises itself as a motor neuron disease and is considered relatively rare. Detailed epidemiological studies of MMN have not been undertaken. We therefore conducted a nationwide survey of MMN in comparison with amyotrophic lateral sclerosis (ALS). This retrospective study examined 47 patients with MMN and 1,051 patients with ALS from major neuromuscular centers in Japan from 2005 to 2009. MMN had a younger age of onset and was more common in males than ALS. The ratio of MMN to ALS patients (0-0.10) varied among the centers, but mostly converged to 0.05. The prevalence was estimated to be 0.3 cases for MMN and 6.63 cases for ALS per 100,000 persons. Twenty-five MMN patients (54.2%) showed conduction block. Thirty-four (75%) of 45 MMN patients received intravenous immunoglobulin exhibited a favorable outcome. It is expected that more sensitive indicators of conduction block or focal demyelinating lesions than currently available MMN diagnostic criteria would further increase the ratio of MMN to ALS patients and the total number of MMN patients who can benefit from treatment. MMN is by no means a rare disorder but should be accurately diagnosed in all neuromuscular centers.<br>  (日)    [継承]
キーワード (推奨): 1. (英) multifocal motor neuropathy (日) 多巣性運動ニューロパチー (読) [継承]
2. (英) amyotrophic lateral sclerosis (日) 筋萎縮性側索硬化症 (読) [継承]
3. (英) nationwide survey (日) 疫学調査 (読) [継承]
4. (英) conduction block (日) 伝導ブロック (読) [継承]
5. (英) intravenous immunoglobulin (日) 免疫グロブリン大量静注療法 (読) [継承]
発行所 (推奨): (英) Societas Neurologica Japonica (日) (読) [継承]
誌名 (必須): 臨床神経学 (日本神経学会)
(pISSN: 0009-918X, eISSN: 1882-0654)

ISSN (任意): 0009-918X
ISSN: 0009-918X (pISSN: 0009-918X, eISSN: 1882-0654)
Title: Rinsho shinkeigaku = Clinical neurology
Title(ISO): Rinsho Shinkeigaku
Supplier: 日本神経学会
Publisher: Japanese Society of Neurology/Nihon Shinkei Gakkai
 (NLM Catalog  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 52 [継承]
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(必須): 920 922 [継承]
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年月日 (必須): 西暦 2012年 0月 初日 (平成 24年 0月 初日) [継承]
URL (任意): http://ci.nii.ac.jp/naid/130004505210/ [継承]
DOI (任意): 10.5692/clinicalneurol.52.920    (→Scopusで検索) [継承]
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NAID (任意): 130004505210 [継承]
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標準的な表示

和文冊子 ● 松井 尚子 : 多巣性運動ニューロパチー:疫学と治療の実態, 臨床神経学, Vol.52, No.11, 920-922, 2012年(0月).
欧文冊子 ● Naoko Matsui : Multifocal motor neuropathy: Current review of epidemiology and treatment, Clinical Neurology, Vol.52, No.11, 920-922, (month)2012.

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