『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Tanimoto Masashi (日) (読)
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学籍番号 (推奨):
[継承]
2. (英) Ota Yukiko (日) (読)
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学籍番号 (推奨):
[継承]
3.堀川 一樹 ([徳島大学.先端研究推進センター.バイオイメージング研究部門])
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学籍番号 (推奨):
[継承]
4. (英) Oda Yoichi (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Auditory input to CNS is acquired coincidentally with development of inner ear after formation of functional afferent pathway in zebrafish.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Auditory perception in vertebrates depends on transduction of sound into neural signals in the inner ear hair cells (HCs) and on transmission of these signals to the brain through auditory (VIIIth) nerve afferents. To investigate the developmental acquisition of auditory inputs by the CNS, we have electrophysiologically and morphologically examined the process of acquisition of auditory responsiveness by zebrafish macular HCs and the Mauthner cells (M-cells) in vivo. The M-cells are a paired large reticulospinal neurons in the hindbrain; they receive direct inputs from the VIIIth nerve afferents and initiate an acoustic startle response. Whole-cell recordings from the M-cells showed that sound-evoked postsynaptic currents were first observed around 40 h postfertilization (hpf); during subsequent development, onset latency decreased and amplitude increased. The appearance and development of microphonic potentials in the inner ear coincided with those of the acoustic responses of the M-cell, whereas the functional auditory circuits from the macular HCs to the M-cell were already formed at 27 hpf. These results suggest that the functional maturation of inner ear after formation of the auditory pathway is a critical process in the acquisition of auditory inputs by CNS neurons.  (日)    [継承]
キーワード (推奨): 1. (英) Acoustic Stimulation (日) (読) [継承]
2. (英) Afferent Pathways (日) (読) [継承]
3. (英) Animals (日) (読) [継承]
4. (英) Animals, Genetically Modified (日) (読) [継承]
5. (英) Auditory Pathways (日) (読) [継承]
6. (英) Central Nervous System (日) (読) [継承]
7. (英) Cochlear Microphonic Potentials (日) (読) [継承]
8. (英) Ear, Inner (日) (読) [継承]
9. (英) Electrophysiology (日) (読) [継承]
10. (英) Evoked Potentials, Auditory (日) (読) [継承]
11.免疫組織化学 (immunohistochemistry) [継承]
12. (英) Neurons (日) (読) [継承]
13. (英) Vestibulocochlear Nerve (日) (読) [継承]
14. (英) Zebrafish (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Neuroscience (Society for Neuroscience)
(pISSN: 0270-6474, eISSN: 1529-2401)

ISSN (任意): 1529-2401
ISSN: 0270-6474 (pISSN: 0270-6474, eISSN: 1529-2401)
Title: The Journal of neuroscience : the official journal of the Society for Neuroscience
Title(ISO): J Neurosci
Publisher: Society for Neuroscience
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 29 [継承]
(必須): 9 [継承]
(必須): 2762 2767 [継承]
都市 (任意):
年月日 (必須): 西暦 2009年 3月 4日 (平成 21年 3月 4日) [継承]
URL (任意):
DOI (任意): 10.1523/JNEUROSCI.5530-08.2009    (→Scopusで検索) [継承]
PMID (任意): 19261871    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) PublicationType: Journal Article  (日)    [継承]
2.(英) PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Masashi Tanimoto, Yukiko Ota, Kazuki Horikawa and Yoichi Oda : Auditory input to CNS is acquired coincidentally with development of inner ear after formation of functional afferent pathway in zebrafish., The Journal of Neuroscience, Vol.29, No.9, 2762-2767, 2009.
欧文冊子 ● Masashi Tanimoto, Yukiko Ota, Kazuki Horikawa and Yoichi Oda : Auditory input to CNS is acquired coincidentally with development of inner ear after formation of functional afferent pathway in zebrafish., The Journal of Neuroscience, Vol.29, No.9, 2762-2767, 2009.

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