『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=298308EID:298308, Map:0, LastModified:2015年11月15日(日) 18:19:23, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[宇都 義浩], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Ishikawa Mami (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Inoue Takahiro (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Inui Toshio (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Kuchiike Daisuke (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Kubo Kentaro (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
6.宇都 義浩 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.応用生命系.応用生物資源学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.応用生命講座])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
7. (英) Nishikata Takahito (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) A novel assay system for macrophage-activating factor activity using a human U937 cell line  (日)    [継承]
副題 (任意):
要約 (任意): (英) Macrophages play important roles in antitumor immunity, and immunotherapy with the group-specific component protein-derived macrophage-activating factor (GcMAF) has been reported to be effective in patients with various types of cancers. However, in macrophage research, it is important to properly evaluate macrophage activity. U937 macrophages were induced by 12-O-tetradecanoyl-13-phorbolacetate (TPA). The phagocytic activity of macrophages was evaluated as the internalized beads ratio. The MAF activity was assessed at 30 min after MAF addition as the activation ratio. We established a novel assay for phagocytic activities using differentiated U937 macrophages. The novel protocol was simple and rapid and was sensitive for GcMAF. This protocol should be useful not only for basic studies, such as those on molecular mechanisms underlying macrophage activation, but also for clinical studies, such as assessment of GcMAF activity prior to clinical use.  (日)    [継承]
キーワード (推奨): 1. (英) Dose-Response Relationship, Drug (日) (読) [継承]
2. (英) Humans (日) (読) [継承]
3. (英) Macrophage Activation (日) (読) [継承]
4. (英) Macrophage-Activating Factors (日) (読) [継承]
5. (英) Macrophages (日) (読) [継承]
6. (英) Phagocytosis (日) (読) [継承]
7. (英) Tetradecanoylphorbol Acetate (日) (読) [継承]
8. (英) U937 Cells (日) (読) [継承]
9. (英) Vitamin D-Binding Protein (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Anticancer Research (International Institute of Anticancer Research(IIAR))
(pISSN: 0250-7005, eISSN: 1791-7530)

ISSN (任意): 1791-7530
ISSN: 0250-7005 (pISSN: 0250-7005, eISSN: 1791-7530)
Title: Anticancer research
Title(ISO): Anticancer Res.
Publisher: International Institute of Anticancer Research
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
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(必須): 34 [継承]
(必須): 8 [継承]
(必須): 4577 4581 [継承]
都市 (任意):
年月日 (必須): 西暦 2014年 8月 初日 (平成 26年 8月 初日) [継承]
URL (任意):
DOI (任意):
PMID (任意): 25075102    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000339773500014 [継承]
Scopus (任意):
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指導教員 (推奨):
備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) KeywordList.Keyword: Gc protein-derived macrophage-activating factor  (日)    [継承]
3.(英) KeywordList.Keyword: GcMAF  (日)    [継承]
4.(英) KeywordList.Keyword: MAF  (日)    [継承]
5.(英) KeywordList.Keyword: U937 cell line  (日)    [継承]
6.(英) KeywordList.Keyword: macrophage-activating factor  (日)    [継承]
7.(英) KeywordList.Keyword: phagocytic activity  (日)    [継承]

標準的な表示

和文冊子 ● Mami Ishikawa, Takahiro Inoue, Toshio Inui, Daisuke Kuchiike, Kentaro Kubo, Yoshihiro Uto and Takahito Nishikata : A novel assay system for macrophage-activating factor activity using a human U937 cell line, Anticancer Research, Vol.34, No.8, 4577-4581, 2014.
欧文冊子 ● Mami Ishikawa, Takahiro Inoue, Toshio Inui, Daisuke Kuchiike, Kentaro Kubo, Yoshihiro Uto and Takahito Nishikata : A novel assay system for macrophage-activating factor activity using a human U937 cell line, Anticancer Research, Vol.34, No.8, 4577-4581, 2014.

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