| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
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| ○著者 (必須): | 1. | 近藤 英司 ([徳島大学.病院.診療科.感覚·皮膚·運動機能科.耳鼻咽喉科・頭頸部外科])
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| 2. | 陣内 自治
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| 3. | (英) Ohnishi Hiroki (日) (読)
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| 4. | (英) Kawata Ikuji (日) (読)
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| 5. | (英) Nakano Seiichi (日) (読)
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| 6. | 合田 正和
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| 7. | 北村 嘉章 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.耳鼻咽喉科学]/[徳島大学.病院.診療科.感覚·皮膚·運動機能科.耳鼻咽喉科・頭頸部外科])
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| 8. | 阿部 晃治
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| 9. | (英) Hoshikawa Hiroshi (日) (読)
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| 10. | (英) Okamoto Hidehiko (日) (読)
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| 11. | 武田 憲昭
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| ○題名 (必須): | □ | (英) Effects of aural stimulation with capsaicin ointment on swallowing function in elderly patients with non-obstructive dysphagia. (日)
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| ○要約 (任意): | □ | (英) In the present study, an attempt was made to examine the effects of aural stimulation with ointment containing capsaicin on swallowing function in order to develop a novel and safe treatment for non-obstructive dysphagia in elderly patients. A prospective pilot, non-blinded, non-controlled study with case series evaluating a new treatment. Secondary hospitals. The present study included 26 elderly patients with non-obstructive dysphagia. Ointment containing 0.025% capsaicin (0.5 g) was applied to the external auditory canal with a cotton swab under otoscope only once or once a day for 7 days before swallowing of a bolus of colored water (3 mL), which was recorded by transnasal videoendoscopy and evaluated according to the endoscopic swallowing score. After a single application of 0.025% capsaicin ointment to the right external auditory canal, the endoscopic swallowing score was significantly decreased, and this effect lasted for 60 minutes. After repeated applications of the ointment to each external auditory canal alternatively once a day for 7 days, the endoscopic swallowing score decreased significantly in patients with more severe non-obstructive dysphagia. Of the eight tube-fed patients of this group, three began direct swallowing exercises using jelly, which subsequently restored their oral food intake. These findings suggest that stimulation of the external auditory canal with ointment containing capsaicin improves swallowing function in elderly patients with non-obstructive dysphagia. By the same mechanism used by angiotensin-converting enzyme inhibitors to induce cough reflex, which has been shown to prevent aspiration pneumonia, aural stimulation with capsaicin may reduce the incidence of aspiration pneumonia in dysphagia patients via Arnold's ear-cough reflex stimulation. (日)
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| ○キーワード (推奨): | 1. | (英) Aged (日) (読)
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| 2. | (英) Aged, 80 and over (日) (読)
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| 3. | (英) Capsaicin (日) (読)
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| 4. | (英) Deglutition Disorders (日) (読)
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| 5. | (英) Ear Canal (日) (読)
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| 6. | (英) Endoscopy (日) (読)
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| 7. | (英) Female (日) (読)
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| 8. | (英) Homes for the Aged (日) (読)
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| 9. | (英) Humans (日) (読)
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| 10. | (英) Japan (日) (読)
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| 11. | (英) Male (日) (読)
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| 12. | (英) Nursing Homes (日) (読)
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| 13. | (英) Ointments (日) (読)
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| 14. | (英) Otoscopes (日) (読)
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| 15. | (英) Pilot Projects (日) (読)
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| 16. | (英) Pneumonia, Aspiration (日) (読)
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| 17. | (英) Prospective Studies (日) (読)
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| 18. | (英) Risk Factors (日) (読)
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| 19. | (英) Video Recording (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Clinical Interventions in Aging (Society for Applied Research in Aging)
(pISSN: 1176-9092, eISSN: 1178-1998)
| ○ISSN (任意): | □ | 1178-1998
ISSN: 1176-9092
(pISSN: 1176-9092, eISSN: 1178-1998) Title: Clinical interventions in agingTitle(ISO): Clin Interv AgingPublisher: Dove Medical Press Ltd (NLM Catalog)
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| ○巻 (必須): | □ | 9
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| ○号 (必須): | □ |
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| ○頁 (必須): | □ | 1661 1667
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2014年 9月 初日 (平成 26年 9月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.2147/CIA.S67602 (→Scopusで検索)
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| ○PMID (任意): | □ | 25328387 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.2147/CIA.S67602 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) OtherID: PMC4198277 (日)
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| 4. | (英) KeywordList.Keyword: Arnold's ear-cough reflex (日)
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| 5. | (英) KeywordList.Keyword: external auditory canal (日)
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| 6. | (英) KeywordList.Keyword: oral food intake (日)
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| 7. | (英) KeywordList.Keyword: swallowing reflex (日)
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