| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | 秦 明子 ([徳島大学.病院.中央診療施設等.糖尿病対策センター])
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| 2. | (英) Yonemoto Koji (日) 米本 孝二 (読) よねもと こうじ
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| 3. | 四釜 洋介
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| 4. | (英) Aki Nanako (日) 安藝 菜奈子 (読) あき ななこ
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| 5. | 小杉 知里
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| 6. | 田村 綾子
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| 7. | 市原 多香子
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| 8. | 南川 貴子 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.看護学系.療養回復ケア看護学]/[徳島大学.医学部.保健学科.看護学専攻.成人·高齢者看護学講座])
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| 9. | 桑村 由美 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.看護学系.女性の健康支援看護学])
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| 10. | (英) Miyoshi Masashi (日) 三好 雅士 (読) みよし まさし
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| 11. | (英) Nakao Takayuki (日) 中尾 隆之 (読) なかお たかゆき
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| 12. | 船木 真理 ([徳島大学.病院.中央診療施設等.糖尿病対策センター])
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| ○題名 (必須): | □ | (英) Cut-off value of total adiponectin for managing risk of developing metabolic syndrome in male Japanese workers. (日)
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| ○要約 (任意): | □ | (英) To determine the optimal cut-off value of serum total adiponectin for managing the risk of developing metabolic syndrome (MetS) in male Japanese workers. A total of 365 subjects without MetS aged 20-60 years were followed up prospectively for a mean of 3.1 years. The accelerated failure-time model was used to estimate time ratio (TR) and cut-off value for developing MetS. During follow-up, 45 subjects developed MetS. Age-adjusted TR significantly declined with decreasing total adiponectin level (≤ 4.9, 5.0-6.6, 6.7-8.8 and ≥ 8.9 μg/ml, P for trend = 0.003). In multivariate analyses, TR of MetS was 0.12 (95% CI 0.02-0.78; P = 0.03) in subjects with total adiponectin level of 5.0-6.6 μg/ml, and 0.15 (95% CI 0.02-0.97; P = 0.047) in subjects with total adiponectin level ≤ 4.9 μg/ml compared with those with total adiponectin level ≥ 8.9 μg/ml. The accelerated failure-time model showed that the optimal cut-off value of total adiponectin for managing the risk of developing MetS was 6.2 μg/ml. In the multivariate-adjusted model, the mean time to the development of MetS was 78% shorter for total adiponectin level ≤ 6.2 μg/ml compared with > 6.2 μg/ml (TR 0.22, 95% CI: 0.08-0.64, P = 0.005). Our findings suggest that the cut-off value for managing the risk of developing MetS is 6.2 μg/ml in male Japanese workers. Subjects with total adiponectin level ≤ 6.2 μg/ml developed MetS more rapidly than did those with total adiponectin level > 6.2 μg/ml. (日)
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| ○キーワード (推奨): |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | PLoS ONE (Public Library of Science)
(eISSN: 1932-6203)
| ○ISSN (任意): | □ | 1932-6203
ISSN: 1932-6203
(eISSN: 1932-6203) Title: PloS oneTitle(ISO): PLoS OnePublisher: Public Library of Science (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 10
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| ○号 (必須): | □ | 2
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| ○頁 (必須): | □ | e0118373 e0118373
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2015年 2月 23日 (平成 27年 2月 23日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1371/journal.pone.0118373 (→Scopusで検索)
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| ○PMID (任意): | □ | 25705909 (→Scopusで検索)
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| ○NAID (任意): |
| ○WOS (任意): | □ | 000350662100175
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| ○Scopus (任意): | □ | 2-s2.0-84923361347
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| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.1371/journal.pone.0118373 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) OtherID: PMC4337907 (日)
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