『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=282656EID:282656, Map:0, LastModified:2014年10月21日(火) 15:39:12, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[安友 康二], Read:継承, Write:継承, Delete:継承.
○種別 (必須): □学術論文 (審査論文) [継承]
○言語 (必須): □英語 [継承]
○招待 (推奨):
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○カテゴリ (推奨):
○共著種別 (推奨):
○学究種別 (推奨):
○組織 (推奨):
○著者 (必須): 1. (英) Sawada Akihisa (日) (読)
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2. (英) Ohga Shouichi (日) (読)
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3. (英) Ishii Eiichi (日) (読)
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4. (英) Inoue Masami (日) (読)
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5. (英) Okada Keiko (日) (読)
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6. (英) Inagaki Jiro (日) (読)
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7. (英) Goto Hiroaki (日) (読)
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8. (英) Suzuki Nobuhiro (日) (読)
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9. (英) Koike Kazutoshi (日) (読)
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10. (英) Atsuta Yoshiko (日) (読)
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11. (英) Suzuki Ritsuro (日) (読)
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12. (英) Yabe Hiromasa (日) (読)
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13. (英) Kawa Keisei (日) (読)
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14. (英) Kato Koji (日) (読)
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15.安友 康二 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.病理系.生体防御医学])
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○題名 (必須): □(英) Feasibility of reduced-intensity conditioning followed by unrelated cord blood transplantation for primary hemophagocytic lymphohistiocytosis: a nationwide retrospective analysis in Japan.  (日)    [継承]
○副題 (任意):
○要約 (任意): □(英)   (日) A nationwide retrospective analysis was performed on patients who received allogeneic hematopoietic stem cell transplantation for primary or familial hemophagocytic lymphohistiocytosis (HLH) in Japan. The present analysis investigated whether reduced-intensity conditioning (RIC) followed by cord blood transplantation (CBT) (RIC-CBT) is feasible, compared to the outcomes of myeloablative conditioning and bone marrow transplantation. Based on the JSHCT data, 53 patients were analyzed. The overall survival rate (OS) was 65.4 ± 6.6 %. RIC-CBT (n = 13) was not inferior to other methods. Patients with a performance status of PS 4 (ECOG scale) with HLH-associated severe organ dysfunction during the initiation of conditioning had extremely poor outcomes. The OS rate in the RIC-CBT patients, excluding those with a performance status 4, was 80.0 ± 12.6 %. RIC may reduce treatment-related mortality; in addition, patients with engraftment failure, which is the main adverse event following RIC-CBT, were successfully rescued with secondary CBT. Unrelated cord blood may represent an alternative source if a patient has no related donor. As a RIC regimen for CBT, 140 mg/m(2) melphalan with fludarabine and anti-lymphocyte globulin or anti-thymocyte globulin may be feasible, but further dosage optimization should be performed in controlled clinical trials.   [継承]
○キーワード (推奨): 1. (英) Adolescent (日) (読) [継承]
2. (英) Allografts (日) (読) [継承]
3. (英) Antilymphocyte Serum (日) (読) [継承]
4. (英) Child (日) (読) [継承]
5. (英) Child, Preschool (日) (読) [継承]
6. (英) Cord Blood Stem Cell Transplantation (日) (読) [継承]
7. (英) Disease-Free Survival (日) (読) [継承]
8. (英) Female (日) (読) [継承]
9. (英) Humans (日) (読) [継承]
10. (英) Immunosuppressive Agents (日) (読) [継承]
11. (英) Infant (日) (読) [継承]
12. (英) Japan (日) (読) [継承]
13. (英) Lymphohistiocytosis, Hemophagocytic (日) (読) [継承]
14. (英) Male (日) (読) [継承]
15. (英) Melphalan (日) (読) [継承]
16. (英) Myeloablative Agonists (日) (読) [継承]
17. (英) Survival Rate (日) (読) [継承]
18. (英) Transplantation Conditioning (日) (読) [継承]
19. (英) Unrelated Donors (日) (読) [継承]
20. (英) Vidarabine (日) (読) [継承]
○発行所 (推奨):
○誌名 (必須): □International Journal of Hematology (日本血液学会)
(pISSN: 0925-5710, eISSN: 1865-3774)

○ISSN (任意): □1865-3774
ISSN: 0925-5710 (pISSN: 0925-5710, eISSN: 1865-3774)
Title: International journal of hematology
Title(ISO): Int J Hematol
Publisher: Springer
 (NLM Catalog)   (医中誌Web)   (Scopus)   (CrossRef)  (Scopus information is found. [need login])
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○巻 (必須): □98 [継承]
○号 (必須): □2 [継承]
○頁 (必須): □223 230 [継承]
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○年月日 (必須): □西暦 2013年 7月 11日 (平成 25年 7月 11日) [継承]
○URL (任意):
○DOI (任意): □10.1007/s12185-013-1391-z    (→Scopusで検索) [継承]
○PMID (任意): □23843148    (→Scopusで検索) [継承]
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○備考 (任意): 1.(英) PublicationType: Clinical Trial  (日)    [継承]
2.(英) PublicationType: Journal Article  (日)    [継承]
3.(英) PublicationType: Multicenter Study  (日)    [継承]
4.(英) PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Akihisa Sawada, Shouichi Ohga, Eiichi Ishii, Masami Inoue, Keiko Okada, Jiro Inagaki, Hiroaki Goto, Nobuhiro Suzuki, Kazutoshi Koike, Yoshiko Atsuta, Ritsuro Suzuki, Hiromasa Yabe, Keisei Kawa, Koji Kato and Koji Yasutomo : Feasibility of reduced-intensity conditioning followed by unrelated cord blood transplantation for primary hemophagocytic lymphohistiocytosis: a nationwide retrospective analysis in Japan., International Journal of Hematology, Vol.98, No.2, 223-230, 2013.
欧文冊子 ● Akihisa Sawada, Shouichi Ohga, Eiichi Ishii, Masami Inoue, Keiko Okada, Jiro Inagaki, Hiroaki Goto, Nobuhiro Suzuki, Kazutoshi Koike, Yoshiko Atsuta, Ritsuro Suzuki, Hiromasa Yabe, Keisei Kawa, Koji Kato and Koji Yasutomo : Feasibility of reduced-intensity conditioning followed by unrelated cord blood transplantation for primary hemophagocytic lymphohistiocytosis: a nationwide retrospective analysis in Japan., International Journal of Hematology, Vol.98, No.2, 223-230, 2013.

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