| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Koichiro irie (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | (英) Tomofuji Takaaki (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Daisuke Ekuni (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | (英) Yasumasa Endo (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 5. | (英) Kenta Kasuyama (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 6. | (英) Azuma Tetsuji (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 7. | 玉木 直文
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 8. | (英) Toshiki Yoneda (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 9. | (英) Manabu Morita (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) Anti-ageing effects of dentifrices containing antioxidative, anti-inflammatory, and anti-bacterial agents (Tomarina) on gingival collagen degradation in rats (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Previous studies have demonstrated the relationship between ageing and oxidative stress. In this study, we examined the effects of topical application of a dentifrice containing anti-oxidative, anti-inflammatory, and anti-bacterial agents (Tomarina®) to the gingival surface on gingival collagen degradation in rats. Fischer 344 male rats (4 or 8 months old) were divided into two groups: experimental group and control group. Tomarina® (the experimental group) or control dentifrice (the control group) was applied 5 days per week for 2 months. In the control group, gingival collagen density decreased with ageing. In the experimental group, the collagen density did not change with ageing, and was greater than that in the control group at 10 months of age (p < 0.0083). In addition, the control group showed an increase in serum oxidative stress with ageing. The experimental group also showed increased serum oxidative stress, but the value was lower than the control group at 10 months of age (p < 0.0083). Furthermore, low expressions of protein oxidative damage in the periodontal tissue were observed in the experimental group, compared to the control group at 6 months and 10 months. These findings indicate that Tomarina® might suppress the effects of ageing on gingival collagen degradation, by decreasing oxidative stress in the rat model. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Aging (日) (読)
| [継承] |
| 2. | (英) Animals (日) (読)
| [継承] |
| 3. | (英) Anti-Bacterial Agents (日) (読)
| [継承] |
| 4. | (英) Anti-Inflammatory Agents (日) (読)
| [継承] |
| 5. | (英) Antioxidants (日) (読)
| [継承] |
| 6. | コラーゲン (collagen)
| [継承] |
| 7. | (英) Dentifrices (日) (読)
| [継承] |
| 8. | フラボノイド (flavonoids)
| [継承] |
| 9. | (英) Gingiva (日) (読)
| [継承] |
| 10. | (英) Male (日) (読)
| [継承] |
| 11. | 酸化ストレス (oxidative stress)
| [継承] |
| 12. | (英) Rats (日) (読)
| [継承] |
| 13. | (英) Rats, Inbred F344 (日) (読)
| [継承] |
| 14. | 活性酸素 (reactive oxygen species/->キーワード[活性酸素種])
| [継承] |
| 15. | (英) Statistics, Nonparametric (日) (読)
| [継承] |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Archives of Oral Biology ([Elsevier])
(pISSN: 0003-9969, eISSN: 1879-1506)
| ○ISSN (任意): | □ | 1879-1506
ISSN: 0003-9969
(pISSN: 0003-9969, eISSN: 1879-1506) Title: Archives of oral biologyTitle(ISO): Arch Oral BiolPublisher: Elsevier Ltd (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 59
| [継承] |
| ○号 (必須): | □ | 1
| [継承] |
| ○頁 (必須): | □ | 60 65
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2014年 1月 初日 (平成 26年 1月 初日)
| [継承] |
| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.archoralbio.2013.09.008 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 24404578 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○WOS (任意): | □ | 000328432300007
| [継承] |
| ○Scopus (任意): | □ | 2-s2.0-84888307856
| [継承] |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) PublicationType: JOURNAL ARTICLE (日)
| [継承] |