| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): | □ | 博士後期課程学生による研究報告
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| ○組織 (推奨): |
| ○著者 (必須): | 1. | 中本 真理子 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.実践栄養学])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 2. | 有澤 孝吉
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | 上村 浩一
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | 勝浦-釜野 桜子 ([徳島大学.大学院ヘルスバイオサイエンス研究部.医療創生科学部門.社会環境衛生学講座.予防医学]/->個人[釜野 桜子])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 5. | (英) Takami Hidenobu (日) (読)
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| ○貢献度 (任意): |
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| 6. | (英) Sawachika Fusakazu (日) (読)
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| [継承] |
| 7. | 山口 美輪
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| ○学籍番号 (推奨): |
| [継承] |
| 8. | (英) Juta Tomoya (日) (読)
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| 9. | 酒井 徹 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.実践栄養学])
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| ○学籍番号 (推奨): |
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| 10. | (英) Toda Eisaku (日) (読)
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| 11. | (英) Mori Kei (日) (読)
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| 12. | (英) Hasegawa Manabu (日) (読)
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| 13. | (英) Tanto Masaharu (日) (読)
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| 14. | (英) Shima Masayuki (日) (読)
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| ○貢献度 (任意): |
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| 15. | (英) Sumiyoshi Yoshio (日) (読)
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| ○貢献度 (任意): |
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| 16. | (英) Morinaga Kenji (日) (読)
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| [継承] |
| 17. | (英) Kodama Kazunori (日) (読)
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| 18. | (英) Suzuki Takaichiro (日) (読)
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| ○貢献度 (任意): |
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| 19. | (英) Nagai Masaki (日) (読)
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| 20. | (英) Satoh Hiroshi (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| ○題名 (必須): | □ | (英) Association between blood levels of PCDDs/PCDFs/dioxin-like PCBs and history of allergic and other diseases in the Japanese population. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Previous studies reported that exposure to dioxins was associated with an increased risk of various diseases in general populations. The aim of this study was to examine the association between levels of dioxins in blood and allergic and other diseases. We conducted a cross-sectional study on 1,063 men and 1,201 women (aged 15-76 years), who were living throughout Japan and not occupationally exposed to dioxins, during 2002-2010. In fasting blood samples, polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like PCBs (DL-PCBs) were analyzed by isotope dilution high-resolution gas chromatography/mass spectrometry. We obtained information on life style and self-reported history of diseases using a questionnaire. Blood pressure, blood levels of hemoglobin A1c, and serum lipids were also measured. Multiple logistic regression models were used to analyze the association between dioxin levels in blood and various diseases. Toxic equivalents of PCDDs/PCDFs and total dioxins showed significant inverse dose-response relationships with atopic dermatitis, after adjustments for potential confounders. The highest quartile for total dioxins had an adjusted odds ratio of 0.26 (95 % confidence interval 0.08-0.70) compared to the reference group (first quartile). The odds ratios for hypertension, diabetes mellitus, hyperlipidemia, gout in men, and gynecologic diseases in women significantly increased with increasing toxic equivalents of PCDDs/PCDFs, DL-PCBs, and total dioxins in blood. The present findings suggest that background exposure to dioxins was associated with reduced risk of atopic dermatitis. The results also support the idea that low-level exposure to dioxins is associated with an increased risk of diabetes, hypertension, and hyperlipidemia. (日)
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| ○キーワード (推奨): | 1. | (英) Adolescent (日) (読)
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| 2. | (英) Adult (日) (読)
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| 3. | (英) Aged (日) (読)
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| 4. | (英) Benzofurans (日) (読)
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| 5. | (英) Cross-Sectional Studies (日) (読)
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| 6. | (英) Dermatitis, Atopic (日) (読)
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| 7. | (英) Diabetes Mellitus (日) (読)
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| 8. | (英) Environmental Exposure (日) (読)
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| 9. | (英) Female (日) (読)
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| 10. | (英) Humans (日) (読)
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| 11. | (英) Hyperlipidemias (日) (読)
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| 12. | (英) Hypertension (日) (読)
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| 13. | (英) Japan (日) (読)
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| 14. | (英) Life Style (日) (読)
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| 15. | (英) Male (日) (読)
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| 16. | (英) Middle Aged (日) (読)
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| 17. | (英) Polychlorinated Biphenyls (日) (読)
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| 18. | (英) Questionnaires (日) (読)
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| 19. | (英) Tetrachlorodibenzodioxin (日) (読)
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| 20. | (英) Young Adult (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | International Archives of Occupational and Environmental Health ([Springer-Verlag])
(pISSN: 0340-0131, eISSN: 1432-1246)
| ○ISSN (任意): | □ | 1432-1246
ISSN: 0340-0131
(pISSN: 0340-0131, eISSN: 1432-1246) Title: International archives of occupational and environmental healthTitle(ISO): Int Arch Occup Environ HealthSupplier: Springer Online Journal ArchivePublisher: Springer (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 86
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| ○号 (必須): | □ | 8
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| ○頁 (必須): | □ | 849 859
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2013年 11月 初日 (平成 25年 11月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1007/s00420-012-0819-8 (→Scopusで検索)
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| ○PMID (任意): | □ | 23014754 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): | □ | 11
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.1007/s00420-012-0819-8 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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