| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○著者 (必須): | 1. | 八木 秀介 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域医療人材育成(医学域)])
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| 2. | 粟飯原 賢一 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).実践地域診療・医科学])
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| 3. | 近藤 剛史
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| 4. | 遠藤 逸朗 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.医用検査学系.生体機能解析学])
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| 5. | 發知 淳子
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| 6. | 伊勢 孝之 ([徳島大学.病院.診療科.内科.循環器内科])
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| 7. | 岩瀬 俊
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| 8. | 赤池 雅史 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.社会医学系.医療教育学])
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| 9. | 松本 俊夫
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| 10. | 佐田 政隆 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.循環器内科学])
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| ○題名 (必須): | □ | (英) High serum parathyroid hormone and calcium are risk factors for hypertension in Japanese patients. (日)
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| ○要約 (任意): | □ | (英) Excess parathyroid hormone (PTH), known as primary hyperparathyroidism (pHPT), results in hypercalcemia and bone loss. Recent studies have shown that PTH is associated with the occurrence of hypertension in Western countries; however, controversy remains regarding high serum levels of PTH and calcium as risk factors for hypertension in Japanese patients. We retrospectively enrolled 114 consecutive Japanese patients who visited our hospital for examination and treatment of hypercalcemia and/or hypertension with serum calcium levels ≥ 9.8 mg/dL. To estimate the prevalence of hypertension, the patients were categorized according to calcium levels into hypercalcemic (10.2-13.4 mg/dL) and normocalcemic (9.8-10.1 mg/dL) groups, which were further categorized into high PTH (50-440 pg/mL) and low PTH (8-49 pg/mL) groups. The prevalence of hypertension was higher in patients with hypercalcemia than in patients with normocalcemia in both the high and low PTH groups. The prevalence of hypertension was higher in patients with high serum PTH levels than in patients with low serum PTH levels in both the hypercalcemic and normocalcemic groups. Logistic multiple regression analysis determined that serum calcium (P < 0.05) and PTH (P < 0.01) levels were positive contributors to hypertension. In conclusion, high serum levels of PTH and calcium are risk factors for hypertension in Japanese patients. (日)
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| ○キーワード (推奨): | 1. | (英) parathyroid hormone (日) (読)
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| 2. | カルシウム (calcium)
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| 3. | 高血圧 (hypertension)
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| ○発行所 (推奨): | □ | 社団法人 日本内分泌学会
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| ○誌名 (必須): | □ | Endocrine Journal ([社団法人 日本内分泌学会])
(pISSN: 0918-8959, eISSN: 1348-4540)
| ○ISSN (任意): | □ | 1348-4540
ISSN: 0918-8959
(pISSN: 0918-8959, eISSN: 1348-4540) Title: Endocrine journalTitle(ISO): Endocr JSupplier: 一般社団法人 日本内分泌学会Publisher: Japan Endocrine Sociey/Nihon Naibunpi Gakkai (NLM Catalog)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 61
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| ○号 (必須): | □ | 7
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| ○頁 (必須): | □ | 727 733
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| ○年月日 (必須): | □ | 西暦 2014年 7月 30日 (平成 26年 7月 30日)
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| ○URL (任意): | □ | http://ci.nii.ac.jp/naid/130004443979/
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| ○DOI (任意): | □ | 10.1507/endocrj.EJ14-0004 (→Scopusで検索)
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| ○PMID (任意): | □ | 24849536 (→Scopusで検索)
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| ○CRID (任意): | □ | 1390001206300211712
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| ○NAID : | □ | 130004443979
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| ○WOS (任意): | □ | 000341226300010
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| ○Scopus (任意): | □ | 2-s2.0-84905190698
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| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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