『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=267715EID:267715, Map:0, LastModified:2018年5月23日(水) 17:08:03, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[西岡 安彦], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
共著種別 (推奨):
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組織 (推奨):
著者 (必須): 1.湯浅 志乃
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2.山口 治隆 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).総合診療医学])
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3. (英) Nakanishi Yoshinori (日) (読)
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4. (英) Kawaminami Shingo (日) (読)
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5.田畑 良
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6. (英) Shimizu Nobuhiko (日) (読)
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7.河野 光宏
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8. (英) Shimizu Teruki (日) (読)
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9. (英) Miyata Junya (日) (読)
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10. (英) Nakayama Mayuko (日) (読)
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11.岸 潤
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12.豊田 優子
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13.西岡 安彦 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.呼吸器・膠原病内科学])
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14.谷 憲治 ([徳島大学.病院.中央診療施設等.総合診療部]/[徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).総合診療医学])
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題名 (必須): (英) Treatment responses and their predictors in patients with rheumatoid arthritis treated with biological agents.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Biological agents represent an important advancement in for the treatment of rheumatoid arthritis (RA), but there is a subset of patients who do not improve despite therapy. This study aimed to determine the efficacy of biological agents for RA and to identify clinical factors that are associated with their response. We studied 98 patients with RA who started an initiating biological agent which was selected from infliximab, etanercept, adalimumab and tociliximab at 4 medical institutions. Etanercept was the most frequently used biological agent followed by infliximab although there was a difference in the selection of the biological agents among medical institutions. We found that etanercept achieved the highest treatment response, remission rate and drug survival rate. A high disease activity in the baseline disease activity score-c-reactive protein (CRP) was shown to be a negative predictor of the treatment response, and high patient global assessment was significantly less likely to achieve a good response. At week 4, decreases in 28 swollen joint counts and CRP were useful as predictors for sustaining the efficacy up to week 48. These data demonstrate that assessments of the disease activity at baseline and the early treatment response may be useful in predicting the efficacy and drug survival rate of biological agents.  (日)    [継承]
キーワード (推奨):
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1349-6867
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 60 [継承]
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(必須): 77 90 [継承]
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年月日 (必須): 西暦 2013年 2月 初日 (平成 25年 2月 初日) [継承]
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DOI (任意): 10.2152/jmi.60.77    (→Scopusで検索) [継承]
PMID (任意): 23614915    (→Scopusで検索) [継承]
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機関リポジトリ : 111302 [継承]
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備考 (任意): 1.(英) Affiliation: Department of General Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan.  (日)    [継承]
2.(英) PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Shino Yuasa, Harutaka Yamaguchi, Yoshinori Nakanishi, Shingo Kawaminami, Ryo Tabata, Nobuhiko Shimizu, Mitsuhiro Kohno, Teruki Shimizu, Junya Miyata, Mayuko Nakayama, Jun Kishi, Yuko Toyoda, Yasuhiko Nishioka and Kenji Tani : Treatment responses and their predictors in patients with rheumatoid arthritis treated with biological agents., The Journal of Medical Investigation : JMI, Vol.60, No.1-2, 77-90, 2013.
欧文冊子 ● Shino Yuasa, Harutaka Yamaguchi, Yoshinori Nakanishi, Shingo Kawaminami, Ryo Tabata, Nobuhiko Shimizu, Mitsuhiro Kohno, Teruki Shimizu, Junya Miyata, Mayuko Nakayama, Jun Kishi, Yuko Toyoda, Yasuhiko Nishioka and Kenji Tani : Treatment responses and their predictors in patients with rheumatoid arthritis treated with biological agents., The Journal of Medical Investigation : JMI, Vol.60, No.1-2, 77-90, 2013.

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