『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=266169EID:266169, Map:0, LastModified:2019年12月4日(水) 10:18:13, Operator:[近久 幸子], Avail:TRUE, Censor:0, Owner:[近久 幸子], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1.清水 紀之
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2.近久 幸子 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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3. (英) Nishi Yuina (日) 西 結奈 (読) にし ゆいな
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学籍番号 (推奨): **** [ユーザ]
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4. (英) Harada Saki (日) 原田 紗希 (読) はらだ さき
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5. (英) Iwaki Yohei (日) (読)
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6.藤原 広明
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7.北岡 和義 ([徳島大学.教養教育院])
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8.志内 哲也 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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9.勢井 宏義 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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題名 (必須): (英) Maternal Dietary Restriction Alters Offspring's Sleep Homeostasis.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Nutritional state in the gestation period influences fetal growth and development. We hypothesized that undernutrition during gestation would affect offspring sleep architecture and/or homeostasis. Pregnant female mice were assigned to either control (fed ad libitum; AD) or 50% dietary restriction (DR) groups from gestation day 12 to parturition. After parturition, dams were fed AD chow. After weaning, the pups were also fed AD into adulthood. At adulthood (aged 8-9 weeks), we carried out sleep recordings. Although offspring mice displayed a significantly reduced body weight at birth, their weights recovered three days after birth. Enhancement of electroencephalogram (EEG) slow wave activity (SWA) during non-rapid eye movement (NREM) sleep was observed in the DR mice over a 24-hour period without changing the diurnal pattern or amounts of wake, NREM, or rapid eye movement (REM) sleep. In addition, DR mice also displayed an enhancement of EEG-SWA rebound after a 6-hour sleep deprivation and a higher threshold for waking in the face of external stimuli. DR adult offspring mice exhibited small but significant increases in the expression of hypothalamic peroxisome proliferator-activated receptor (Ppar) and brain-specific carnitine palmitoyltransferase 1 (Cpt1c) mRNA, two genes involved in lipid metabolism. Undernutrition during pregnancy may influence sleep homeostasis, with offspring exhibiting greater sleep pressure.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Body Weight (日) (読) [継承]
3. (英) Caloric Restriction (日) (読) [継承]
4. (英) Carnitine O-Palmitoyltransferase (日) (読) [継承]
5. (英) Diet (日) (読) [継承]
6. (英) Electroencephalography (日) (読) [継承]
7. (英) Female (日) (読) [継承]
8. (英) Gene Expression (日) (読) [継承]
9. (英) Homeostasis (日) (読) [継承]
10. (英) Hypothalamus (日) (読) [継承]
11. (英) Mice (日) (読) [継承]
12. (英) PPAR alpha (日) (読) [継承]
13. (英) Pregnancy (日) (読) [継承]
14. (英) Prenatal Exposure Delayed Effects (日) (読) [継承]
15. (英) Sleep (日) (読) [継承]
16. (英) Sleep, REM (日) (読) [継承]
17. (英) Wakefulness (日) (読) [継承]
発行所 (推奨):
誌名 (必須): PLoS ONE (Public Library of Science)
(eISSN: 1932-6203)

ISSN (任意): 1932-6203
ISSN: 1932-6203 (eISSN: 1932-6203)
Title: PloS one
Title(ISO): PLoS ONE
Publisher: Public Library of Science
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 8 [継承]
(必須): 5 [継承]
(必須): e64263 e64263 [継承]
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年月日 (必須): 西暦 2013年 5月 31日 (平成 25年 5月 31日) [継承]
URL (任意):
DOI (任意): 10.1371/journal.pone.0064263    (→Scopusで検索) [継承]
PMID (任意): 23741310    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000319799900022 [継承]
Scopus (任意): 2-s2.0-84878536785 [継承]
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備考 (任意): 1.(英) Affiliation: Department of Integrative Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.  (日)    [継承]
2.(英) PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Noriyuki Shimizu, Sachiko Chikahisa, Yuina Nishi, Saki Harada, Yohei Iwaki, Hiroaki Fujihara, Kazuyoshi Kitaoka, Tetsuya Shiuchi and Hiroyoshi Sei : Maternal Dietary Restriction Alters Offspring's Sleep Homeostasis., PLoS ONE, Vol.8, No.5, e64263, 2013.
欧文冊子 ● Noriyuki Shimizu, Sachiko Chikahisa, Yuina Nishi, Saki Harada, Yohei Iwaki, Hiroaki Fujihara, Kazuyoshi Kitaoka, Tetsuya Shiuchi and Hiroyoshi Sei : Maternal Dietary Restriction Alters Offspring's Sleep Homeostasis., PLoS ONE, Vol.8, No.5, e64263, 2013.

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