| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Teshigawara Kiyoshi (日) (読)
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| 2. | 保坂 利男
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| 3. | 山口 美輪
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| 4. | (英) Terada Eri (日) (読)
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| 5. | (英) Kisyuku Yuka (日) (読)
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| 6. | (英) Fukunaga Keiko (日) (読)
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| 7. | (英) Hirata Yohko (日) (読)
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| 8. | (英) Jambaldorj Bayasgalan (日) (読)
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| 9. | 原田 永勝
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| 10. | 酒井 徹 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.実践栄養学])
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| 11. | 中屋 豊
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| ○題名 (必須): | □ | (英) Long-term treatment with hyperbaric air improves hyperlipidemia of db/db mice. (日)
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| ○要約 (任意): | □ | (英) Hyperbaric air (HBA) is used to improve healing of wounds including diabetic ulcer. The aim of this study was to clarify the effects of HBA exposure on lipid and glucose metabolism in db/db mice. HBA did not influence the weight of db/db mice. Serum levels of free fatty acid and triglyceride, but not glucose and insulin, were significantly decreased after 6 weeks of treatment with HBA. The mRNA expressions of CPT-1, PPAR and PGC-1 genes, which are related to lipid metabolism, were significantly up-regulated in the muscle and liver. Increases in TNF and MCP1 mRNA, which impaired lipid metabolism, were also attenuated by HBA treatment. These results suggest that exposure of HBA could have beneficial effects on lipid metabolism in patients with type 2 diabetes mellitus. (日)
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| ○キーワード (推奨): | 1. | (英) Animals (日) (読)
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| 2. | (英) Base Sequence (日) (読)
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| 3. | (英) Blood Glucose (日) (読)
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| 4. | (英) Carnitine O-Palmitoyltransferase (日) (読)
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| 5. | (英) Chemokine CCL2 (日) (読)
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| 6. | (英) DNA Primers (日) (読)
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| 7. | (英) Diabetes Mellitus, Type 2 (日) (読)
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| 8. | (英) Fatty Acids, Nonesterified (日) (読)
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| 9. | (英) Humans (日) (読)
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| 10. | (英) Hyperbaric Oxygenation (日) (読)
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| 11. | (英) Hyperlipidemias (日) (読)
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| 12. | インスリン (insulin)
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| 13. | (英) Lipid Metabolism (日) (読)
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| 14. | (英) Male (日) (読)
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| 15. | (英) Mice (日) (読)
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| 16. | (英) Mice, Mutant Strains (日) (読)
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| 17. | (英) PPAR alpha (日) (読)
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| 18. | (英) RNA, Messenger (日) (読)
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| 19. | (英) Trans-Activators (日) (読)
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| 20. | (英) Triglycerides (日) (読)
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| 21. | (英) Tumor Necrosis Factor-alpha (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
| ○ISSN (任意): | □ | 1349-6867
ISSN: 1343-1420
(pISSN: 1343-1420, eISSN: 1349-6867) Title: The journal of medical investigation : JMITitle(ISO): J Med InvestSupplier: 徳島大学Publisher: Tokushima Daigaku Igakubu (NLM Catalog)
(Webcat Plus)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 57
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| ○号 (必須): | □ | 3-4
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| ○頁 (必須): | □ | 224 231
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2010年 8月 初日 (平成 22年 8月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.2152/jmi.57.224 (→Scopusで検索)
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| ○PMID (任意): | □ | 20847521 (→Scopusで検索)
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| ○CRID (任意): |
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| ○機関リポジトリ : | □ | 79137
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Nutrition and Metabolism, Institute of Health Biosciences, the University of Tokushima Graduate School, Tokushima, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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