| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○著者 (必須): | 1. | (英) Masuda Motoshi (日) 増田 基司 (読) ますだ もとし
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| ○学籍番号 (推奨): | □ | ****
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| 2. | 榎本 崇宏 ([徳島大学.大学院社会産業理工学研究部.理工学域.電気電子系.電気電子システム分野]/[徳島大学.理工学部.理工学科.電気電子システムコース.電気電子システム講座])
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| 3. | (英) Suzuki Asato (日) 鈴木 安里 (読) すずき あさと
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| ○学籍番号 (推奨): | □ | ****
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| 4. | 芥川 正武 ([徳島大学.大学院社会産業理工学研究部.理工学域.電気電子系.電気電子システム分野]/[徳島大学.理工学部.理工学科.電気電子システムコース.電気電子システム講座])
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| 5. | 北脇 知己 ([岡山大学])
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| 6. | 北岡 和義 ([徳島大学.教養教育院])
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| 7. | 田中 弘之 ([鳴門教育大学])
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| 8. | 小原 繁
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| 9. | 吉﨑 和男
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| 10. | 小中 信典
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| 11. | 木内 陽介
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| ○題名 (必須): | □ | (英) Evaluation of blood flow velocity waveform in common carotid artery using multi-branched arterial segment model of human arteries (日) ヒトの多枝動脈モデルを用いた総頸動脈血流速度波形の評価
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| ○要約 (任意): | □ | (英) Arteriosclerosis is considered to be a major cause of cardiovascular diseases, which account for approximately 30% of the causes of death in the world. We have recently demonstrated a strong correlation between arteriosclerosis (arterial elasticity) and two characteristics: maximum systolic velocity (S1) and systolic second peak velocity (S2) of the common carotid artery flow velocity waveform (CCFVW). The CCFVW can be measured by using a small portable measuring device. However, there is currently no theoretical evidence supporting the causes of the relation between CCFVW and arterial elasticity, or the origin of the CCFVW characteristics. In this study, the arterial blood flow was simulated using a one-dimensional systemic arterial segments model of human artery in order to conduct a qualitative evaluation of the relationship between arterial elasticity and the characteristics of CCFVW. The simulation was carried out based on the discretized segments with the physical properties of a viscoelastic tube (the cross-sectional area at the proximal and terminal ends, the length, and the compliance per unit area of the tube (CS)). The findings obtained through this study revealed that the simulated CCFVW had shape similar characteristics to that of the measured CCFVW. Moreover, when the compliance CS of the model was decreased, the first peak of the simulated-CCFVW decreased and the second peak increased. Further, by separating the anterograde pulse wave and the reflected pulse wave, which form the CCFVW, we found that the decrease in the first peak of the simulated CCFVW was due to the arrival of a reflected pulse wave from the head after the common carotid artery toward the arrival of a anterograde pulse wave ejected directly from the heart and that the increase in the second peak resulted from the arrival of the peak of the reflected pulse wave from the thoracic aorta. These results establish that the CCFVW characteristics contribute to the assessment of arterial elasticity. (日) 総頸動脈血流速度波形と動脈弾性の関係について，1次元流体解析モデルを用いて検討している．動脈モデルはヒトの全身の主要な動脈を多枝セグメントモデルとして構築したものを用い，動脈弾性を変化させた時の総頸動脈の血流速度波形を求めた結果，動脈弾性の変化により血流速度波形が変化することを示した．これにより総頸動脈の血流速度波形を調べることにより動脈硬化を評価することができる可能性を示した．
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| ○キーワード (推奨): | 1. | (英) Common carotid (日) (読)
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| 2. | (英) Hemodynamics (日) (読)
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| 3. | (英) Fluid simulation (日) (読)
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| 4. | (英) Artery segments model (日) (読)
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| 5. | (英) Artery elasticity (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Biomedical Signal Processing and Control ([Elsevier])
(eISSN: 1746-8094)
| ○ISSN (任意): | □ | 1746-8094
ISSN: 1746-8094
(pISSN: 1746-8094, eISSN: 1746-8108) Title: Biomedical signal processing and controlTitle(ISO): Biomed Signal Process ControlPublisher: Elsevier B.V. (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 8
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| ○号 (必須): | □ | 6
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| ○頁 (必須): | □ | 509 519
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| ○年月日 (必須): | □ | 西暦 2013年 11月 初日 (平成 25年 11月 初日)
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| ○DOI (任意): | □ | 10.1016/j.bspc.2013.05.005 (→Scopusで検索)
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| ○WOS (任意): | □ | 000329885000005
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| ○Scopus (任意): | □ | 2-s2.0-84878849060
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