『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=259663EID:259663, Map:0, LastModified:2014年2月25日(火) 19:19:34, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[工藤 保誠], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.広島大学 [継承]
著者 (必須): 1. (英) Hatano Hiroko (日) (読)
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[継承]
2. (英) Ogawa Ikuko (日) (読)
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[継承]
3. (英) Shigeishi Hideo (日) (読)
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4.工藤 保誠 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔生命科学])
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5. (英) Ohta Kouji (日) (読)
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[継承]
6. (英) Higashikawa Koichiro (日) (読)
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7.武知 正晃
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8.高田 隆 ([広島大学])
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[継承]
9.鎌田 伸之
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題名 (必須): (英) Expression of receptor for hyaluronan-mediated motility (RHAMM) in ossifying fibromas.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Fibro-osseous lesions of the jaw are poorly understood because of a significant overlap of clinical, radiological and histological features among the various types, though they present distinct patterns of disease progression. An ossifying fibroma is associated with significant cosmetic and functional disturbances, as it shows expansive proliferation. Thus, it is important to establish a specific marker, as well as clearly elucidate its etiology for diagnosis and proper treatment. We previously established immortalized cell lines from human ossifying fibromas of the jaw and found that they highly expressed the receptor for hyaluronan (HA)-mediated motility (RHAMM). In this study, we examined the expression of RHAMM mRNA in 65 fibro-osseous lesions, including ossifying fibroma, fibrous dysplasia and osseous dysplasia, as well as 5 normal jaws, using real-time RT-PCR and immunohistochemistry assays. RHAMM mRNA and protein expression were significantly elevated in the ossifying fibroma specimens. These results suggest that detection of upregulated RHAMM expression in an ossifying fibroma assists with differential diagnosis and has a key role in elucidation of its pathophysiology.  (日)    [継承]
キーワード (推奨): 1. (英) Adolescent (日) (読) [継承]
2. (英) Adult (日) (読) [継承]
3. (英) Aged (日) (読) [継承]
4. (英) Aged, 80 and over (日) (読) [継承]
5. (英) Alkaline Phosphatase (日) (読) [継承]
6. (英) Antigens, CD44 (日) (読) [継承]
7. (英) Bone Neoplasms (日) (読) [継承]
8. (英) Case-Control Studies (日) (読) [継承]
9. (英) Extracellular Matrix Proteins (日) (読) [継承]
10. (英) Female (日) (読) [継承]
11. (英) Fibroma, Ossifying (日) (読) [継承]
12. (英) Humans (日) (読) [継承]
13. (英) Immunohistochemistry (日) (読) [継承]
14. (英) Integrin-Binding Sialoprotein (日) (読) [継承]
15. (英) Male (日) (読) [継承]
16. (英) Middle Aged (日) (読) [継承]
17. (英) Osteocalcin (日) (読) [継承]
18. (英) Prognosis (日) (読) [継承]
19. (英) RNA, Messenger (日) (読) [継承]
20. (英) Real-Time Polymerase Chain Reaction (日) (読) [継承]
21. (英) Tumor Markers, Biological (日) (読) [継承]
22. (英) Up-Regulation (日) (読) [継承]
23. (英) Young Adult (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Histology and Histopathology (Consejería de Sanidad de la Comunidad Autónoma/Sociedad Española de Histología e Ingeniería Tisular)
(pISSN: 0213-3911, eISSN: 1699-5848)

ISSN (任意): 1699-5848
ISSN: 0213-3911 (pISSN: 0213-3911, eISSN: 1699-5848)
Title: Histology and histopathology
Title(ISO): Histol Histopathol
Publisher: Plaza Fuensanta
 (NLM Catalog  (Scopus (Scopus information is found. [need login])
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(必須): 28 [継承]
(必須): 4 [継承]
(必須): 473 480 [継承]
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年月日 (必須): 西暦 2013年 2月 5日 (平成 25年 2月 5日) [継承]
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DOI (任意):
PMID (任意): 23382057    (→Scopusで検索) [継承]
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WOS (任意): 000316190000007 [継承]
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備考 (任意): 1.(英) Affiliation: Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.  (日)    [継承]
2.(英) PublicationType: JOURNAL ARTICLE  (日)    [継承]

標準的な表示

和文冊子 ● Hiroko Hatano, Ikuko Ogawa, Hideo Shigeishi, Yasusei Kudo, Kouji Ohta, Koichiro Higashikawa, Masaaki Takechi, Takashi Takata and Nobuyuki Kamata : Expression of receptor for hyaluronan-mediated motility (RHAMM) in ossifying fibromas., Histology and Histopathology, Vol.28, No.4, 473-480, 2013.
欧文冊子 ● Hiroko Hatano, Ikuko Ogawa, Hideo Shigeishi, Yasusei Kudo, Kouji Ohta, Koichiro Higashikawa, Masaaki Takechi, Takashi Takata and Nobuyuki Kamata : Expression of receptor for hyaluronan-mediated motility (RHAMM) in ossifying fibromas., Histology and Histopathology, Vol.28, No.4, 473-480, 2013.

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