『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1.黒田 暁生 ([徳島大学.先端酵素学研究所.基幹研究部門])
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2. (英) Yasuda Tetsuyuki (日) (読)
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3. (英) Takahara Mitsuyoshi (日) (読)
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4. (英) Sakamoto Fumie (日) (読)
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5. (英) Kasami Ryuichi (日) (読)
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6. (英) Miyashita Kazuyuki (日) (読)
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7.吉田 守美子 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.血液・内分泌代謝内科学])
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8. (英) Kondo Eri (日) (読)
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9.粟飯原 賢一 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).実践地域診療・医科学])
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10.遠藤 逸朗 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.医用検査学系.生体機能解析学])
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11. (英) Matsuoka Taka-Aki (日) (読)
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12. (英) Kaneto Hideaki (日) (読)
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13.松本 俊夫
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14. (英) Shimomura Iichiro (日) (読)
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15.松久 宗英 ([徳島大学.先端酵素学研究所.基幹研究部門]/徳島大学病院アンチエイジングセンター センター長(併任))
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題名 (必須): (英) Carbohydrate-to-Insulin Ratio Is Estimated from 300-400 Divided by Total Daily Insulin Dose in Type 1 Diabetes Patients Who Use the Insulin Pump.  (日)    [継承]
副題 (任意):
要約 (任意): (英)   (日) Abstract Background: To optimize insulin dose using insulin pump, basal and bolus insulin doses are widely calculated from total daily insulin dose (TDD). It is recommended that total daily basal insulin dose (TBD) is 50% of TDD and that the carbohydrate-to-insulin ratio (CIR) equals 500 divided by TDD. We recently reported that basal insulin requirement is approximately 30% of TDD. We therefore investigated CIR after adjustment of the proper basal insulin rate. Subjects and Methods: Forty-five Japanese patients with type 1 diabetes were investigated during several weeks of hospitalization. The patients were served standard diabetes meals (25-30 kcal/kg of ideal body weight). Each meal omission was done to confirm basal insulin rate. Target blood glucose level was set at 100 and 150 mg/dL before and 2 h after each meal, respectively. After the basal insulin rate was fixed and target blood glucose levels were achieved, TBD, CIR, TDD, and their products were determined. Results: Mean (±SD) blood glucose levels before and 2 h after meals were 121±47 and 150±61 mg/dL, respectively. TDD was 31.5±9.0 U, and TBD was 27.0±6.5% of TDD. CIR×TDD of breakfast was significantly lower than those of lunch and supper (288±73 vs. 408±92 and 387±83, respectively; P<0.01). Conclusions: CIR has diurnal variance and is estimated from the formula CIR=300/TDD at breakfast or CIR=400/TDD at lunch and supper in type 1 diabetes patients. These results indicate that the insulin dose has been underestimated by using previously established calculations.   [継承]
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誌名 (必須): Diabetes Technology & Therapeutics (Mary Ann Liebert, Inc. publishers)
(pISSN: 1520-9156, eISSN: 1557-8593)

ISSN (任意): 1557-8593
ISSN: 1520-9156 (pISSN: 1520-9156, eISSN: 1557-8593)
Title: Diabetes technology & therapeutics
Title(ISO): Diabetes Technol Ther
Publisher: Mary Ann Liebert Inc.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 14 [継承]
(必須): 11 [継承]
(必須): 1077 1080 [継承]
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年月日 (必須): 西暦 2012年 11月 14日 (平成 24年 11月 14日) [継承]
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DOI (任意): 10.1089/dia.2012.0109    (→Scopusで検索) [継承]
PMID (任意): 23101953    (→Scopusで検索) [継承]
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WOS (任意): 000310573300017 [継承]
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備考 (任意): 1.(英) Affiliation: 1 Diabetes Therapeutics and Research Center, The University of Tokushima , Tokushima, Japan .  (日)    [継承]
2.(英) PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Akio Kuroda, Tetsuyuki Yasuda, Mitsuyoshi Takahara, Fumie Sakamoto, Ryuichi Kasami, Kazuyuki Miyashita, Sumiko Yoshida, Eri Kondo, Ken-ichi Aihara, Itsuro Endo, Taka-Aki Matsuoka, Hideaki Kaneto, Toshio Matsumoto, Iichiro Shimomura and Munehide Matsuhisa : Carbohydrate-to-Insulin Ratio Is Estimated from 300-400 Divided by Total Daily Insulin Dose in Type 1 Diabetes Patients Who Use the Insulin Pump., Diabetes Technology & Therapeutics, Vol.14, No.11, 1077-1080, 2012.
欧文冊子 ● Akio Kuroda, Tetsuyuki Yasuda, Mitsuyoshi Takahara, Fumie Sakamoto, Ryuichi Kasami, Kazuyuki Miyashita, Sumiko Yoshida, Eri Kondo, Ken-ichi Aihara, Itsuro Endo, Taka-Aki Matsuoka, Hideaki Kaneto, Toshio Matsumoto, Iichiro Shimomura and Munehide Matsuhisa : Carbohydrate-to-Insulin Ratio Is Estimated from 300-400 Divided by Total Daily Insulin Dose in Type 1 Diabetes Patients Who Use the Insulin Pump., Diabetes Technology & Therapeutics, Vol.14, No.11, 1077-1080, 2012.

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