『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=253057)

EID=253057EID:253057, Map:0, LastModified:2013年8月12日(月) 13:56:09, Operator:[松井 栄里], Avail:TRUE, Censor:0, Owner:[安友 康二], Read:継承, Write:継承, Delete:継承.
○種別 (必須): □学術論文 (審査論文) [継承]
○言語 (必須): □英語 [継承]
○招待 (推奨):
○審査 (推奨):
○カテゴリ (推奨):
○共著種別 (推奨):
○学究種別 (推奨):
○組織 (推奨):
○著者 (必須): 1. (英) Nishi Masanori (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
2. (英) Nishimura Ryosei (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
3. (英) Suzuki Nobuhiro (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
4. (英) Sawada Akihisa (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
5. (英) Okamura Takayuki (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
6. (英) Fujita Naoto (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
7. (英) Kanai Rie (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
8. (英) Yano Jun (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
9. (英) Adachi Souichi (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
10. (英) Yasumi Takahiro (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
11. (英) Sato Emiko (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
12.安友 康二 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.病理系.生体防御医学])
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
13. (英) Ishii Eiichi (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
14. (英) Ohga Shouichi (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
○題名 (必須): □(英) Reduced-intensity conditioning in unrelated donor cord blood transplantation for familial hemophagocytic lymphohistiocytosis.  (日)    [継承]
○副題 (任意):
○要約 (任意): □(英) Familial hemophagocytic lymphohistiocytosis (FHL) is a disorder of immune homeostasis characterized by fever, cytopenias, hepatosplenomegaly, and coagulopathy. We studied the outcomes of 13 FHL patients who underwent the first unrelated cord blood transplantation (UCBT) after non-myeloablative conditionings. The major regimen consisted of fludarabine (FLU; n = 12)+melphalan (MEL; n = 11)± low-dose total body irradiation (TBI 2-4 Gy; n = 6). The median age at presentation and period to UCBT were 6 and 5 months, respectively. Central nervous system (CNS) disease developed in one infant at diagnosis, and in two others until UCBT. HLH activity was controlled in all but one at the time of UCBT. Ten patients had early engraftment on median day 21 with no grade >2 treatment-related toxicity and two controllable grade >2 acute GVHD. Two patients with early rejection successfully underwent subsequent UCBT after myeloablative conditioning. Two others had late graft failure following mixed donor chimerism. Two deaths occurred from HLH; early liver failure and late CNS disease. Of 11 FLU+MEL-conditioned patients, the frequency of disease-free complete engraftment was higher for MEL (120 mg/m(2) )+TBI, or high-dose MEL (180 mg/m(2) ) than for others (83% vs. 25%, p = 0.036). The FLU+MEL-based non-myeloablative regimen was acceptable for FHL infants undergoing UCBT, although further studies will be needed for confirmation.  (日)    [継承]
○キーワード (推奨): 1. (英) Blood Component Transfusion (日) (読) [継承]
2. (英) Blood Donors (日) (読) [継承]
3. (英) Child, Preschool (日) (読) [継承]
4. (英) Combined Modality Therapy (日) (読) [継承]
5. (英) Cord Blood Stem Cell Transplantation (日) (読) [継承]
6. (英) Disease-Free Survival (日) (読) [継承]
7. (英) Female (日) (読) [継承]
8. (英) Graft Survival (日) (読) [継承]
9. (英) Graft vs Host Disease (日) (読) [継承]
10. (英) Humans (日) (読) [継承]
11. (英) Infant (日) (読) [継承]
12. (英) Infant, Newborn (日) (読) [継承]
13. (英) Japan (日) (読) [継承]
14. (英) Lymphohistiocytosis, Hemophagocytic (日) (読) [継承]
15. (英) Male (日) (読) [継承]
16. (英) Melphalan (日) (読) [継承]
17. (英) Reoperation (日) (読) [継承]
18. (英) Retrospective Studies (日) (読) [継承]
19. (英) Salvage Therapy (日) (読) [継承]
20. (英) Transplantation Conditioning (日) (読) [継承]
21. (英) Treatment Outcome (日) (読) [継承]
22. (英) Vidarabine (日) (読) [継承]
23. (英) Whole-Body Irradiation (日) (読) [継承]
○発行所 (推奨):
○誌名 (必須): □American Journal of Hematology ([Wiley Periodicals, Inc.])
(pISSN: 0361-8609, eISSN: 1096-8652)

○ISSN (任意): □1096-8652
ISSN: 0361-8609 (pISSN: 0361-8609, eISSN: 1096-8652)
Title: American journal of hematology
Title(ISO): Am J Hematol
Publisher: Wiley
 (NLM Catalog)   (Wiley)   (Scopus)   (CrossRef)  (Scopus information is found. [need login])
[継承]
[継承]
○巻 (必須): □87 [継承]
○号 (必須): □6 [継承]
○頁 (必須): □637 639 [継承]
○都市 (任意):
○年月日 (必須): □西暦 2012年 4月 10日 (平成 24年 4月 10日) [継承]
○URL (任意):
○DOI (任意): □10.1002/ajh.23190    (→Scopusで検索) [継承]
○PMID (任意): □22488407    (→Scopusで検索) [継承]
○CRID (任意):
○WOS (任意): □000304249400015 [継承]
○Scopus (任意):
○評価値 (任意):
○被引用数 (任意):
○指導教員 (推奨):
○備考 (任意): 1.(英) Affiliation: Department of Pediatrics, Saga University Hospital, Saga, Japan.  (日)    [継承]
2.(英) PublicationType: Evaluation Studies  (日)    [継承]
3.(英) PublicationType: Letter  (日)    [継承]

標準的な表示

和文冊子 ● Masanori Nishi, Ryosei Nishimura, Nobuhiro Suzuki, Akihisa Sawada, Takayuki Okamura, Naoto Fujita, Rie Kanai, Jun Yano, Souichi Adachi, Takahiro Yasumi, Emiko Sato, Koji Yasutomo, Eiichi Ishii and Shouichi Ohga : Reduced-intensity conditioning in unrelated donor cord blood transplantation for familial hemophagocytic lymphohistiocytosis., American Journal of Hematology, Vol.87, No.6, 637-639, 2012.
欧文冊子 ● Masanori Nishi, Ryosei Nishimura, Nobuhiro Suzuki, Akihisa Sawada, Takayuki Okamura, Naoto Fujita, Rie Kanai, Jun Yano, Souichi Adachi, Takahiro Yasumi, Emiko Sato, Koji Yasutomo, Eiichi Ishii and Shouichi Ohga : Reduced-intensity conditioning in unrelated donor cord blood transplantation for familial hemophagocytic lymphohistiocytosis., American Journal of Hematology, Vol.87, No.6, 637-639, 2012.

関連情報

Number of session users = 0, LA = 0.44, Max(EID) = 414354, Max(EOID) = 1117931.