| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Kurimoto Shin-ichiro (日) 栗本 慎一郎 (読)
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| 2. | 柏田 良樹
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| 3. | (英) Lee Kuo-Hsiung (日) (読)
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| 4. | 高石 喜久 ([徳島大学.デザイン型AI教育研究センター])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| ○題名 (必須): | □ | (英) Triterpenes and a triterpene glucoside from Dysoxylum cumingianum and their cytotoxicity. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Six triterpenes and a triterpene glucoside were isolated from the MeOH extract of the leaves of Dysoxylum cumingianum together with three known triterpenes. Their structures were elucidated by extensive spectroscopic analyses. In cytotoxicity assays against three human cancer cell lines, including a multi-drug resistant cancer cell line (KB-C2), compounds 1, 2 and 5 demonstrated significantly enhanced cytotoxicity against KB-C2 cells in the presence of 2.5 μM colchicine, as compared with those in the absence of colchicine. This result suggested that these triterpenes might show some MDR-reversing effects. (日)
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| ○キーワード (推奨): | 1. | (英) Antineoplastic Agents, Phytogenic (日) (読)
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| 2. | (英) Cell Line, Tumor (日) (読)
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| 3. | (英) Colchicine (日) (読)
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| 4. | (英) Drug Resistance, Multiple (日) (読)
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| 5. | (英) Glucosides (日) (読)
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| 6. | (英) Humans (日) (読)
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| 7. | (英) Meliaceae (日) (読)
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| 8. | (英) Molecular Structure (日) (読)
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| 9. | (英) Neoplasms (日) (読)
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| 10. | (英) Phytotherapy (日) (読)
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| 11. | (英) Plant Extracts (日) (読)
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| 12. | (英) Plant Leaves (日) (読)
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| 13. | (英) Triterpenes (日) (読)
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| 14. | (英) Tubulin Modulators (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Phytochemistry ([Elsevier Science])
(pISSN: 0031-9422, eISSN: 1873-3700)
| ○ISSN (任意): | □ | 1873-3700
ISSN: 0031-9422
(pISSN: 0031-9422, eISSN: 1873-3700) Title: PhytochemistryTitle(ISO): PhytochemistryPublisher: Elsevier Ltd (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 72
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| ○号 (必須): | □ | 17
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| ○頁 (必須): | □ | 2205 2211
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2011年 12月 初日 (平成 23年 12月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.phytochem.2011.08.002 (→Scopusで検索)
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| ○PMID (任意): | □ | 21899865 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Graduate School of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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