『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=245294EID:245294, Map:0, LastModified:2013年9月2日(月) 15:44:05, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[木戸 博], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Fujimoto Cisa (日) (読)
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学籍番号 (推奨):
[継承]
2.武田 憲昭 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.耳鼻咽喉科学])
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[継承]
3. (英) Matsunaga A (日) (読)
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[継承]
4. (英) Sawada A (日) (読)
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[継承]
5. (英) Tanaka T (日) (読)
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[継承]
6. (英) Kimoto Takashi (日) (読)
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学籍番号 (推奨):
[継承]
7. (英) Shinahara Wakako (日) (読)
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学籍番号 (推奨):
[継承]
8. (英) Sawabuchi Takako (日) (読)
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学籍番号 (推奨):
[継承]
9. (英) Yamaguchi Miyoko (日) (読)
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[継承]
10. (英) Hayama M (日) (読)
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学籍番号 (推奨):
[継承]
11.楊河 宏章 ([徳島大学.病院.中央診療施設等.総合臨床研究センター])
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[継承]
12.矢野 仁康
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[継承]
13.木戸 博 ([徳島大学.先端酵素学研究所.重点研究部門])
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貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Induction and maintenance of anti-influenza antigen-specific nasal secretory IgA levels and serum IgG levels after influenza infection in adults.  (日)    [継承]
副題 (任意):
要約 (任意): (英) To determine the induction and changes in anti-influenza virus secretory IgA (s-IgA) levels in nasal washes and serum IgG levels in patients with influenza. The study recruited 16 patients with influenza aged 35.6 ± 9.6 years in 2007/2008 and 2008/2009 seasons. Nasal washes and serum were obtained throughout the first year. Anti-viral s-IgA levels and neutralization activities in nasal washes, and serum anti-viral IgG levels and hemagglutination inhibition (HI) titers were measured. Anti-viral(H1N1) s-IgA to total IgA ratio and neutralizing antibody titer were low in nasal washes of all patients, whereas serum levels of anti-viral IgG and HI titers varied widely at day 1.4 ± 1.0 postinfection. Both nasal s-IgA and serum IgG levels later increased significantly, reaching peak levels at day 9.6 ± 3.3 postinfection. The induced nasal s-IgA then returned toward the initial levels within 300 days, although the levels at day 143 ± 70 were 3.03-fold of the initial. Individual serum IgG levels also returned toward the initial levels within 300 days, although the mean levels remained high probably because of re-infection in a subgroup of patients. Although influenza A (H3N2) was a minor epidemic subtype in both flu seasons, a significant rise in nasal anti-viral (H3N2) s-IgA levels and a slightly increase in serum IgG levels were noted. Low levels of nasal anti-viral s-IgA and neutralizing antibody were noted compared with a wide range of serum anti-viral IgG and HI titers at the onset of infection. Elevated s-IgA and IgG returned toward the initial levels within 300 days of infection with minor exceptions.  (日)    [継承]
キーワード (推奨): 1. (英) Adult (日) (読) [継承]
2. (英) Antibodies, Viral (日) (読) [継承]
3. (英) Female (日) (読) [継承]
4. (英) Hemagglutination Inhibition Tests (日) (読) [継承]
5. (英) Humans (日) (読) [継承]
6. (英) Immunoglobulin A, Secretory (日) (読) [継承]
7. (英) Immunoglobulin G (日) (読) [継承]
8. (英) Influenza, Human (日) (読) [継承]
9. (英) Male (日) (読) [継承]
10. (英) Middle Aged (日) (読) [継承]
11. (英) Nasal Mucosa (日) (読) [継承]
12. (英) Neutralization Tests (日) (読) [継承]
13. (英) Orthomyxoviridae (日) (読) [継承]
14. (英) Retrospective Studies (日) (読) [継承]
15. (英) Serum (日) (読) [継承]
16. (英) Young Adult (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Influenza and Other Respiratory Viruses (International Society for Influenza and other Respiratory Virus Diseases)
(pISSN: 1750-2640, eISSN: 1750-2659)

ISSN (任意): 1750-2659
ISSN: 1750-2640 (pISSN: 1750-2640, eISSN: 1750-2659)
Title: Influenza and other respiratory viruses
Title(ISO): Influenza Other Respir Viruses
Publisher: Blackwell Publishing Inc.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 396 403 [継承]
都市 (任意):
年月日 (必須): 西暦 2012年 6月 初日 (平成 24年 6月 初日) [継承]
URL (任意):
DOI (任意): 10.1111/j.1750-2659.2011.00330.x    (→Scopusで検索) [継承]
PMID (任意): 22226319    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1111/j.1750-2659.2011.00330.x  (日)    [継承]
2.(英) Article.Affiliation: Department of Otolaryngology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Cisa Fujimoto, Noriaki Takeda, A Matsunaga, A Sawada, T Tanaka, Takashi Kimoto, Wakako Shinahara, Takako Sawabuchi, Miyoko Yamaguchi, M Hayama, Hiroaki Yanagawa, Mihiro Yano and Hiroshi Kido : Induction and maintenance of anti-influenza antigen-specific nasal secretory IgA levels and serum IgG levels after influenza infection in adults., Influenza and Other Respiratory Viruses, Vol.6, No.6, 396-403, 2012.
欧文冊子 ● Cisa Fujimoto, Noriaki Takeda, A Matsunaga, A Sawada, T Tanaka, Takashi Kimoto, Wakako Shinahara, Takako Sawabuchi, Miyoko Yamaguchi, M Hayama, Hiroaki Yanagawa, Mihiro Yano and Hiroshi Kido : Induction and maintenance of anti-influenza antigen-specific nasal secretory IgA levels and serum IgG levels after influenza infection in adults., Influenza and Other Respiratory Viruses, Vol.6, No.6, 396-403, 2012.

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