『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Yang P. (日) (読)
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学籍番号 (推奨):
[継承]
2. (英) Hirose T. (日) (読)
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3. (英) Hasegawa T. (日) (読)
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4. (英) Seki K. (日) (読)
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5.中西 秀樹
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6. (英) Hizawa K. (日) (読)
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[継承]
題名 (必須): (英) Ultrastructural heterogeneity of acquired intradermal melanocytic nevus cells  (日)    [継承]
副題 (任意):
要約 (任意): (英) The present ultrastructural evaluation of 12 acquired intradermal melanocytic nevi revealed that in contrast to the nested epithelioid melanocytic nevus cells of the upper dermis, the spindle nevus cells of the deep dermis showed perineurial differentiation, exhibiting a spindly configuration characterized by a melanosome-free cytoplasm that showed extremely slender bipolar contour and contained abundant intermediate filaments, a decreased number of cytoplasmic organelles, and, significantly, a fair number of plasmalemmal pinocytotic vesicles. The nevic corpuscles were found to consist of laminated slender cytoplasm showing subcellular conformation similar to that of the spindle nevus cells. By immunohistochemistry, many spindle nevus cells and nevic corpuscles were immunoreactive for nerve growth factor receptor. All the nevus cells were immunoreactive for vimentin and S-100 protein, and negative for protein gene product 9.5, epithelial membrane antigen, Leu-7, and myelin basic protein. Characteristically, protein gene product 9.5 immunohistochemistry revealed numerous immunoreactive axons intermingled with the spindle nevus cells in the deep portion. All the PGP9.5-immunoreactive axons were observed by immunoelectron microscope to be unmyelinated and always ensheathed by a thin cytoplasmic process of Schwann cells but not nevus cells. These findings indicate that differentiation plasticity exists in the various nevus cells, with the epithelioid nevus cells and the spindle nevus cells displaying more ultrastructural and immunophenotypical characteristics of melanocyte and perineurial cells, respectively, suggesting that a pluripotential cell of neural crest origin accounts for the histogenesis of this lesion.  (日)    [継承]
キーワード (推奨): 1. (英) Humans (日) (読) [継承]
2.免疫組織化学 (immunohistochemistry) [継承]
3. (英) Immunophenotyping (日) (読) [継承]
4. (英) Microscopy, Immunoelectron (日) (読) [継承]
5. (英) Nevus, Intradermal (日) (読) [継承]
6. (英) Schwann Cells (日) (読) [継承]
7. (英) Tumor Cells, Cultured (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Ultrastructural Pathology (Informa Healthcare)
(pISSN: 0191-3123, eISSN: 1521-0758)

ISSN (任意): 0191-3123
ISSN: 0191-3123 (pISSN: 0191-3123, eISSN: 1521-0758)
Title: Ultrastructural pathology
Title(ISO): Ultrastruct Pathol
Publisher: Taylor & Francis
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 20 [継承]
(必須): 3 [継承]
(必須): 255 261 [継承]
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年月日 (必須): 西暦 1996年 5月 初日 (平成 8年 5月 初日) [継承]
URL (任意):
DOI (任意):
PMID (任意): 8727069    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): A1996UL53600009 [継承]
Scopus (任意): 2-s2.0-0030006386 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) MedlineDate: 1996 May-Jun  (日)    [継承]

標準的な表示

和文冊子 ● P. Yang, T. Hirose, T. Hasegawa, K. Seki, Hideki Nakanishi and K. Hizawa : Ultrastructural heterogeneity of acquired intradermal melanocytic nevus cells, Ultrastructural Pathology, Vol.20, No.3, 255-261, 1996.
欧文冊子 ● P. Yang, T. Hirose, T. Hasegawa, K. Seki, Hideki Nakanishi and K. Hizawa : Ultrastructural heterogeneity of acquired intradermal melanocytic nevus cells, Ultrastructural Pathology, Vol.20, No.3, 255-261, 1996.

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