『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Tomioka Reiko (日) 冨岡 麗子 (読) とみおか れいこ
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貢献度 (任意):
学籍番号 (推奨):
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2.谷 憲治 ([徳島大学.病院.中央診療施設等.総合診療部]/[徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).総合診療医学])
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[継承]
3.佐藤 恵子
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4. (英) Suzuka Chiyuki (日) 鈴鹿 千幸 (読) すずか ちゆき
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5.豊田 優子
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6.岸 潤
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7.曽根 三郎
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題名 (必須): (英) Observations on the occurrence of exacerbations in clinical course of systemic lupus erythematosus  (日)    [継承]
副題 (任意):
要約 (任意): (英) Systemic lupus erythematosus (SLE) is a chronic disease that is characterized by an undulating course of exacerbations and remissions, and a major determinant of long-term prognosis is organ damage consequent to tissue injury that accompanies disease activity and toxicity of therapy. In this study, we evaluated which patients with SLE will develop an exacerbation and whether factors can be identified to predict the development of an exacerbation. Fifty-seven SLE patients (52 females) were included in this study. The exacerbation of SLE was found in 15 patients (26.3%). A relatively increased incidence of an exacerbation was found in younger SLE patients. An increased percentage of patients who had lupus nephritis at the time of diagnosis of SLE was found in patients with a subsequent exacerbation when compared with that in those without it. Increased incidence of an exacerbation was observed in patients who had decreased number of WBC and platelets, decreased level of C3 and CH50, and the presence positivity of anti-Sm antibodies at the time of the diagnosis. This study suggests that age, renal involvement, and the presence of decreased number of WBC and platelets, decreased level of complements anti-Sm antibodies are predictors of exacerbation.  (日)    [継承]
キーワード (推奨): 1. (英) Adult (日) (読) [継承]
2. (英) Age Factors (日) (読) [継承]
3. (英) Antibodies, Antinuclear (日) (読) [継承]
4. (英) Biological Markers (日) (読) [継承]
5. (英) Complement System Proteins (日) (読) [継承]
6. (英) Disease Progression (日) (読) [継承]
7. (英) Female (日) (読) [継承]
8. (英) Forecasting (日) (読) [継承]
9. (英) Humans (日) (読) [継承]
10. (英) Leukocyte Count (日) (読) [継承]
11. (英) Lupus Erythematosus, Systemic (日) (読) [継承]
12. (英) Lupus Nephritis (日) (読) [継承]
13. (英) Male (日) (読) [継承]
14. (英) Middle Aged (日) (読) [継承]
15. (英) Monitoring, Physiologic (日) (読) [継承]
16. (英) Platelet Count (日) (読) [継承]
17. (英) Ribonucleoproteins, Small Nuclear (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 112 119 [継承]
都市 (任意):
年月日 (必須): 西暦 2008年 2月 初日 (平成 20年 2月 初日) [継承]
URL (任意):
DOI (任意): 10.2152/jmi.55.112    (→Scopusで検索) [継承]
PMID (任意): 18319553    (→Scopusで検索) [継承]
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機関リポジトリ : 110847 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Internal Medicine and Molecular Therapeutics, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Reiko Tomioka, Kenji Tani, Keiko Sato, Chiyuki Suzuka, Yuko Toyoda, Jun Kishi and Saburo Sone : Observations on the occurrence of exacerbations in clinical course of systemic lupus erythematosus, The Journal of Medical Investigation : JMI, Vol.55, No.1,2, 112-119, 2008.
欧文冊子 ● Reiko Tomioka, Kenji Tani, Keiko Sato, Chiyuki Suzuka, Yuko Toyoda, Jun Kishi and Saburo Sone : Observations on the occurrence of exacerbations in clinical course of systemic lupus erythematosus, The Journal of Medical Investigation : JMI, Vol.55, No.1,2, 112-119, 2008.

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