| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): |
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| ○組織 (推奨): | 1. | 徳島大学.医学部
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| 2. | 徳島大学.工学部.機械工学科.生産システム講座 (〜2023年3月31日)
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| ○著者 (必須): | 1. | (英) Kajiura Kiyoshi (日) (読)
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| 2. | 加藤 真介
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| 3. | 西良 浩一 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.運動機能外科学])
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| 4. | (英) Ikata Takaaki (日) (読)
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| 5. | (英) Goel K. Vijay (日) (読)
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| 6. | 村上 理一
| ○役割 (任意): | □ | (英) (日) 計画，実験，考察，論文執筆
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| ○題名 (必須): | □ | (英) Slippage mechanism of pediatric spondylolysis:biomechanical study using immature calf spines (日)
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| ○副題 (任意): | □ | (英) Discussion based on a biomechanical study using immature calf spines (日)
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| ○要約 (任意): | □ | (英) This study analyzed the skeletal-age-dependent strength of the lumbar growth plate to resist anterior shearing forces using the MTS system in the immature calf spine with pars defects. To clarify the pathomechanism of the skeletal-age-dependent incidence of slippage in pediatric patients with pars defects by comparing the strength of the lumbar growth plate among three skeletal age groups. Isthmic spondylolisthesis occurs and progresses more frequently during the growth period, whereas it is rare afterward. However, little evidence has been demonstrated to elucidate the etiology. For this study, 15 lumbar functional spine units were divided into three groups according to their skeletal ages. Five were from neonates (Group 1), five from calves approximately 2 months old (Group 2), and five from calves about 24 months old (Group 3). An anterior shearing force was applied to each specimen until failure, after bilateral pars defects were created. Failure load (newtons) and displacement at failure (millimeters) were calculated from the load-displacement curve. The site of failure was confirmed by plain radiograph. All 15 functional spine units failed at the growth plate. The failure load was 242.79 +/- 46.05 N in Group 1, 986.40 +/- 124.16 N in Group 2, and 2024.54 +/- 245.53 N in Group 3. Statistically significant differences were found among the three groups (P < 0.05). The displacement at failure was 7.52 +/- 1.84 mm in Group 1, 11.10 +/- 2.30 mm in Group 2, and 8.15 +/- 2.66 mm in Group 3. There were no significant differences among the groups. The results indicate that the strength of the growth plate, the weakest link in this model, against anterior shearing forces depends on the skeletal maturity, and that the biomechanical weakness of the growth plate plays an important role in the slippage mechanism. (日) 脊椎分離症のメカニズムを明らかにするために若年牛の背骨を使ったすべり曲げ試験を行い若年期固有の骨構造が脊椎分離に与える影響を定量的に検討し，骨構造が大きな影響を与えることを解明した．
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| ○キーワード (推奨): | 1. | (英) Aging (日) (読)
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| 2. | (英) Animals (日) (読)
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| 3. | (英) Animals, Newborn (日) (読)
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| 4. | (英) Bone Development (日) (読)
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| 5. | (英) Cattle (日) (読)
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| 6. | (英) Disease Models, Animal (日) (読)
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| 7. | (英) Growth Plate (日) (読)
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| 8. | (英) In Vitro Techniques (日) (読)
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| 9. | (英) Lumbar Vertebrae (日) (読)
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| 10. | (英) Radiography (日) (読)
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| 11. | (英) Spondylolysis (日) (読)
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| 12. | (英) Stress, Mechanical (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Spine ([Lippincott Williams & Wilkins])
(pISSN: 0362-2436, eISSN: 1528-1159)
| ○ISSN (任意): | □ | 0362-2436
ISSN: 0362-2436
(pISSN: 0362-2436, eISSN: 1528-1159) Title: SpineTitle(ISO): Spine (Phila Pa 1976)Publisher: Wolters Kluwer Health (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 26
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| ○号 (必須): | □ | 20
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| ○頁 (必須): | □ | 2208 2213
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2001年 10月 1日 (平成 13年 10月 1日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1097/00007632-200110150-00010 (→Scopusで検索)
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| ○PMID (任意): | □ | 11598509 (→Scopusで検索)
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| ○CRID (任意): |
| ○Scopus (任意): | 1. | 2-s2.0-0035887334
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| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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