『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=227644)

EID=227644EID:227644, Map:0, LastModified:2018年12月6日(木) 13:23:58, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[三宅 雅人], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Hayashi Shinichiro (日) (読)
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2.三宅 雅人 ([徳島大学.先端酵素学研究所.重点研究部門])
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3. (英) Watanabe Kouichi (日) (読)
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4. (英) Aso Hisashi (日) (読)
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5. (英) Hayashi Seigo (日) (読)
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6. (英) Ohwada Shyuichi (日) (読)
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7. (英) Yamaguchi Takahiro (日) (読)
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題名 (必須): (英) Myostatin preferentially down-regulates the expression of fast 2x myosin heavy chain in cattle.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Myostatin is involved in an inhibitor of muscular growth and differentiation. Myoblasts derived from double-muscled Japanese shorthorn cattle (DM myoblasts) with absence of functional myostatin had higher abilities to proliferate and differentiate than myoblasts derived from normal-muscled cattle (NM myoblasts). In DM myoblasts, mRNA expressions of fetal myosin heavy chain (MyHC) in growth medium and of fast 2a and 2x MyHC in fusion medium were significantly greater than that in NM myoblasts. No significant difference existed in expressions of embryonic and slow MyHC mRNA between DM and NM myoblasts. The expression of MyoD mRNA was suppressed in myoblasts by administration of myostatin. Two cloned DM myoblast strains (DMc) were established. Addition of myostatin for DMc resulted in less myotube formation and suppression of mRNA expression of fast 2x MyHC. These findings suggest that the endogenous myostatin preferentially down-regulates the expression of the fast 2x MyHC and participates in differentiation of myofiber types during early bovine myogenesis.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Cattle (日) (読) [継承]
3. (英) Cells, Cultured (日) (読) [継承]
4. (英) Down-Regulation (日) (読) [継承]
5. (英) Muscle, Skeletal (日) (読) [継承]
6. (英) Myosin Heavy Chains (日) (読) [継承]
7. (英) Myostatin (日) (読) [継承]
8. (英) RNA, Messenger (日) (読) [継承]
9. (英) Transforming Growth Factor beta (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Proceedings of the Japan Academy. Series B, Physical and biological sciences ([日本学士院])
(pISSN: 0386-2208, eISSN: 1349-2896)

ISSN (任意): 1349-2896
ISSN: 0386-2208 (pISSN: 0386-2208, eISSN: 1349-2896)
Title: Proceedings of the Japan Academy. Series B, Physical and biological sciences
Title(ISO): Proc Jpn Acad Ser B Phys Biol Sci
Supplier: 日本学士院
Publisher: Nippon Gakushiin/Japan Academy
 (NLM Catalog  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 84 [継承]
(必須): 8 [継承]
(必須): 354 362 [継承]
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年月日 (必須): 西暦 2008年 0月 初日 (平成 20年 0月 初日) [継承]
URL (任意):
DOI (任意): 10.2183/pjab.84.354    (→Scopusで検索) [継承]
PMID (任意): 18941308    (→Scopusで検索) [継承]
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WOS (任意): 000260895400010 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Laboratory of Functional Morphology, Department of Animal Biology, Graduate School of Agricultural Science, Tohoku University, Miyagi, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Shinichiro Hayashi, Masato Miyake, Kouichi Watanabe, Hisashi Aso, Seigo Hayashi, Shyuichi Ohwada and Takahiro Yamaguchi : Myostatin preferentially down-regulates the expression of fast 2x myosin heavy chain in cattle., Proceedings of the Japan Academy. Series B, Physical and biological sciences, Vol.84, No.8, 354-362, 2008.
欧文冊子 ● Shinichiro Hayashi, Masato Miyake, Kouichi Watanabe, Hisashi Aso, Seigo Hayashi, Shyuichi Ohwada and Takahiro Yamaguchi : Myostatin preferentially down-regulates the expression of fast 2x myosin heavy chain in cattle., Proceedings of the Japan Academy. Series B, Physical and biological sciences, Vol.84, No.8, 354-362, 2008.

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