『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=227288)

EID=227288EID:227288, Map:0, LastModified:2013年11月8日(金) 14:06:03, Operator:[三木 ちひろ], Avail:TRUE, Censor:0, Owner:[[学科長]/[徳島大学.医学部.保健学科]], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Tomita Masanori (日) 富田 雅典 (読) とみた まさのり
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Maeda Munetoshi (日) 前田 宗利 (読) まえだ むねとし
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.前澤 博
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.宇佐美 徳子 ([政府.文部省.高エネルギー加速器研究機構])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5.小林 克己 ([独立行政法人 物質·材料研究機構])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Bystander Cell Killing in Normal Human Fibroblasts is Induced by Synchrotron X-ray Microbeams  (日)    [継承]
副題 (任意):
要約 (任意): (英) Abstract The radiation-induced bystander response is defined as a response in cells that have not been directly targeted by radiation but that are in the neighborhood of cells that have been directly exposed. In the work described here, it is shown that bystander cell killing of normal human fibroblast WI-38 cells was induced by synchrotron microbeam X radiation. Cell nuclei in confluent WI-38 cells were irradiated with the microbeam. All of the cells on the dish were harvested and plated 24 h after irradiation. It was found that the bystander cell killing effect showed a parabolic relationship to the radiation dose when five cells were irradiated. At doses above 1.9 Gy, the surviving fraction increased to approximately 1.0. This suggests that induction of bystander cell killing may require some type of activity in the targeted cells, because the dose resulting in 37% cell survival was about 2.0 Gy. Bystander cell killing was suppressed by a pretreatment with aminoguanidine [an inhibitor of inducible nitric oxide (NO) synthase] or carboxy-PTIO (a scavenger of NO). These results suggest that NO is the chief initiator/mediator of bystander cell killing induced by X-ray microbeams.  (日)    [継承]
キーワード (推奨): 1. (英) bystander (日) (読) [継承]
2. (英) human fiblobrasts (日) (読) [継承]
3. (英) synchrotron (日) (読) [継承]
4. (英) microbeams (日) (読) [継承]
5. (英) X-rays (日) (読) [継承]
発行所 (推奨): (英) Radiation Research Society (日) (読) [継承]
誌名 (必須): Radiation Research (Radiation Research Society)
(pISSN: 0033-7587, eISSN: 1938-5404)

ISSN (任意): 1938-5404
ISSN: 0033-7587 (pISSN: 0033-7587, eISSN: 1938-5404)
Title: Radiation research
Title(ISO): Radiat Res
Publisher: Radiation Research Society
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 173 [継承]
(必須): 3 [継承]
(必須): 380 385 [継承]
都市 (任意):
年月日 (必須): 西暦 2010年 1月 初日 (平成 22年 1月 初日) [継承]
URL (任意):
DOI (任意): 10.1667/RR1995.1    (→Scopusで検索) [継承]
PMID (任意): 20199223    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Radiation Safety Research Center, Central Research Institute of Electric Power Industry, Tokyo, Japan. mstomita@criepi.denken.or.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Masanori Tomita, Munetoshi Maeda, Hiroshi Maezawa, Noriko Usami and Katsumi Kobayashi : Bystander Cell Killing in Normal Human Fibroblasts is Induced by Synchrotron X-ray Microbeams, Radiation Research, Vol.173, No.3, 380-385, 2010.
欧文冊子 ● Masanori Tomita, Munetoshi Maeda, Hiroshi Maezawa, Noriko Usami and Katsumi Kobayashi : Bystander Cell Killing in Normal Human Fibroblasts is Induced by Synchrotron X-ray Microbeams, Radiation Research, Vol.173, No.3, 380-385, 2010.

関連情報

Number of session users = 3, LA = 1.35, Max(EID) = 383864, Max(EOID) = 1026622.