| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○共著種別 (推奨): |
| ○学究種別 (推奨): | □ | 博士課程学生による研究報告
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| ○組織 (推奨): | 1. | 徳島大学.大学院ヘルスバイオサイエンス研究部.医療創生科学部門.社会環境衛生学講座.予防医学 (2004年4月1日〜2015年3月31日)
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| ○著者 (必須): | 1. | (英) Kitayama Atsushi (日) (読)
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| 2. | 有澤 孝吉 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.社会医学系.予防医学])
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| 3. | 上村 浩一
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| 4. | 日吉 峰麗
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| 5. | (英) Takami Hidenobu (日) (読)
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| 6. | (英) Sawachika Fusakazu (日) (読)
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| 7. | 山口 美輪
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| 8. | (英) Nakamoto Mariko (日) (読)
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| 9. | (英) Hasegawa Manabu (日) (読)
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| 10. | (英) Tanto Masaharu (日) (読)
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| 11. | (英) Shima Masayuki (日) (読)
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| 12. | (英) Sumiyoshi Yoshio (日) (読)
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| 13. | (英) Morinaga Kenji (日) (読)
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| 14. | (英) Kodama Kazunori (日) (読)
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| 15. | (英) Suzuki Taka-ichiro (日) (読)
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| 16. | (英) Nagai Masaki (日) (読)
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| 17. | (英) Satoh Hiroshi (日) (読)
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| ○題名 (必須): | □ | (英) Correlations of fish intake and plasma docosahexaenoic acid levels with each congener of PCDDs/PCDFs/dioxin-like PCBs in blood from the Japanese population (日)
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| ○要約 (任意): | □ | (英) The purpose of the present study was to investigate the factors associated with blood levels of each congener of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (DL-PCBs) in the Japanese population. A cross-sectional study was performed on 1,656 subjects (755 men and 901 women) aged 15-73 years, who were living in 90 different areas of 30 prefectures in Japan. Blood levels of 29 PCDD, PCDF, and DL-PCB congeners were determined by high-resolution gas chromatography/mass spectrometry. In addition, a questionnaire survey on life style, including dietary habit, was carried out. The median total toxicity equivalent (TEQ) was 17 pgTEQ/g lipid. After adjustment for age, sex, body mass index, smoking habit, and consumption of other food groups, six PCDDs/PCDFs with 4-6 substituted chlorine atoms and 10 DL-PCBs, but not HeptaCDD/F or OctaCDD, showed significant positive correlations with the frequency of intake of fish and shellfish. Furthermore, significant positive relationships were also found between plasma levels of docosahexaenoic acid (DHA), a biomarker of fish intake, and 10 PCDDs/PCDFs with 4-6 chlorine atoms and 10 DL-PCBs. The partial correlation coefficients with plasma DHA were significantly higher for DL-PCBs than for PCDDs/PCDFs, and partial correlation coefficients for PCDDs/PCDFs significantly decreased with increasing number of chlorine atoms (Spearman r = -0.80, P = 0.001). Blood levels of PCDDs/PCDFs with 4-6 chlorine atoms and DL-PCBs were positively associated with fish intake in the Japanese population. These results may be explained by the higher degree of bioaccumulation of these congeners in fish and shellfish in the ecosystem, and the high consumption of fish among the Japanese population. (日)
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| ○キーワード (推奨): | 1. | (英) Adolescent (日) (読)
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| 2. | (英) Adult (日) (読)
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| 3. | (英) Aged (日) (読)
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| 4. | (英) Animals (日) (読)
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| 5. | (英) Benzofurans (日) (読)
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| 6. | (英) Cross-Sectional Studies (日) (読)
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| 7. | (英) Docosahexaenoic Acids (日) (読)
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| 8. | (英) Environmental Monitoring (日) (読)
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| 9. | (英) Female (日) (読)
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| 10. | (英) Fishes (日) (読)
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| 11. | (英) Food Contamination (日) (読)
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| 12. | (英) Food Habits (日) (読)
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| 13. | (英) Humans (日) (読)
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| 14. | 日本 (Japan)
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| 15. | (英) Male (日) (読)
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| 16. | (英) Middle Aged (日) (読)
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| 17. | (英) Polychlorinated Biphenyls (日) (読)
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| 18. | (英) Polymers (日) (読)
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| 19. | (英) Seafood (日) (読)
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| 20. | (英) Tetrachlorodibenzodioxin (日) (読)
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| 21. | (英) Water Pollutants, Chemical (日) (読)
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| 22. | (英) Young Adult (日) (読)
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| ○発行所 (推奨): | □ | Springer
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| ○誌名 (必須): | □ | International Archives of Occupational and Environmental Health ([Springer-Verlag])
(pISSN: 0340-0131, eISSN: 1432-1246)
| ○ISSN (任意): | □ | 1432-1246
ISSN: 0340-0131
(pISSN: 0340-0131, eISSN: 1432-1246) Title: International archives of occupational and environmental healthTitle(ISO): Int Arch Occup Environ HealthSupplier: Springer Online Journal ArchivePublisher: Springer (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 84
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| ○号 (必須): | □ | 8
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| ○頁 (必須): | □ | 927 951
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| ○年月日 (必須): | □ | 西暦 2011年 11月 17日 (平成 23年 11月 17日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1007/s00420-011-0618-7 (→Scopusで検索)
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| ○PMID (任意): | □ | 21298441 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Preventive Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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