『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=221393)

EID=221393EID:221393, Map:0, LastModified:2012年10月2日(火) 20:14:44, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[安井 夏生], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Suzuki Kayo (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
2.松井 好人
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学籍番号 (推奨):
[継承]
3.遠藤 健次
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[継承]
4. (英) Kubo Takahiro (日) (読)
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[継承]
5. (英) Hasegawa Tadashi (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
6. (英) Kimura Tomoatsu (日) (読)
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学籍番号 (推奨):
[継承]
7. (英) Ohtani Osamu (日) (読)
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学籍番号 (推奨):
[継承]
8.安井 夏生
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貢献度 (任意):
学籍番号 (推奨):
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題名 (必須): (英) Myxoid liposarcoma with EWS-CHOP type 1 fusion gene.  (日)    [継承]
副題 (任意):
要約 (任意): (英) In myxoid liposarcoma (MLS), the t(12;16)(q13;p11) chromosomal translocation and its resultant fusion transcript, the human translocation liposarcoma (TLS)-CCAAT/enhancer binding protein (C/EBP) homologous protein (CHOP), are found in the majority of cases. On the other hand, the variant translocation, t(12;22)(q13;q12) creating the Ewing sarcoma (EWS)-CHOP fusion transcript, is detectable in a limited number of cases. Tissue from MLS arising in the left thigh of a 19-year-old female was analyzed for possible detection of chromosome translocation and fusion transcript. Fluorescent in situ hybridization (FISH) and reverse transcription-polymerase chain reaction (RT-PCR) methods were used. FISH analysis demonstrated a rearrangement in the CHOP gene. RT-PCR analysis confirmed the presence of EWS-CHOP chimeric transcript type 1, in which exon 7 of EWS was in-frame fused to exon 2 of CHOP with a serine (AGT) to methionine (ATG) transition at the junction. The patient underwent a radical segmental resection including a left vastus medialis musclectomy. Sixty months following the surgical resection, the patient was alive with no evidence of disease. Analysis of MLS with EWS-CHOP variant transcripts, type 1 through type 4, including this case together with 15 cases in the literature, indicated that MLS with type 1 fusion transcript may show a more favorable clinical behavior than MLS with other types of fusion transcript.  (日)    [継承]
キーワード (推奨): 1. (英) Adult (日) (読) [継承]
2. (英) Chromosomes, Human, Pair 12 (日) (読) [継承]
3. (英) Chromosomes, Human, Pair 22 (日) (読) [継承]
4. (英) Female (日) (読) [継承]
5. (英) Humans (日) (読) [継承]
6. (英) In Situ Hybridization, Fluorescence (日) (読) [継承]
7. (英) Liposarcoma, Myxoid (日) (読) [継承]
8. (英) Magnetic Resonance Imaging (日) (読) [継承]
9. (英) Oncogene Proteins, Fusion (日) (読) [継承]
10. (英) RNA, Messenger (日) (読) [継承]
11. (英) RNA-Binding Protein EWS (日) (読) [継承]
12. (英) Retrospective Studies (日) (読) [継承]
13. (英) Reverse Transcriptase Polymerase Chain Reaction (日) (読) [継承]
14. (英) Transcription Factor CHOP (日) (読) [継承]
15. (英) Transcription, Genetic (日) (読) [継承]
16. (英) Translocation, Genetic (日) (読) [継承]
17. (英) Young Adult (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Anticancer Research (International Institute of Anticancer Research(IIAR))
(pISSN: 0250-7005, eISSN: 1791-7530)

ISSN (任意): 1791-7530
ISSN: 0250-7005 (pISSN: 0250-7005, eISSN: 1791-7530)
Title: Anticancer research
Title(ISO): Anticancer Res
Publisher: International Institute of Anticancer Research
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 30 [継承]
(必須): 11 [継承]
(必須): 4679 4683 [継承]
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年月日 (必須): 西暦 2010年 11月 30日 (平成 22年 11月 30日) [継承]
URL (任意):
DOI (任意):
PMID (任意): 21115923    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000285237100040 [継承]
Scopus (任意):
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指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Departments of Orthopaedic Surgery, University of Toyama, Toyama 930-0194, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Case Reports  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Kayo Suzuki, Yoshito Matsui, Kenji Endo, Takahiro Kubo, Tadashi Hasegawa, Tomoatsu Kimura, Osamu Ohtani and Natsuo Yasui : Myxoid liposarcoma with EWS-CHOP type 1 fusion gene., Anticancer Research, Vol.30, No.11, 4679-4683, 2010.
欧文冊子 ● Kayo Suzuki, Yoshito Matsui, Kenji Endo, Takahiro Kubo, Tadashi Hasegawa, Tomoatsu Kimura, Osamu Ohtani and Natsuo Yasui : Myxoid liposarcoma with EWS-CHOP type 1 fusion gene., Anticancer Research, Vol.30, No.11, 4679-4683, 2010.

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