『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=220633EID:220633, Map:0, LastModified:2013年7月2日(火) 16:00:27, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[安井 武史], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.SPIE The International Society for Optical Engineering [継承]
著者 (必須): 1.安井 武史 ([徳島大学.ポストLEDフォトニクス研究所]/[徳島大学.理工学部.理工学科.機械科学コース.生産工学講座])
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2. (英) Tohno Yoshiyuki (日) (読)
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3.荒木 勉 ([大阪大学])
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学籍番号 (推奨):
[継承]
題名 (必須): (英) Characterization of collagen orientation in human dermis by two-dimensional second-harmonic-generation polarimetry  (日)    [継承]
副題 (任意):
要約 (任意): (英) We have proposed an optical probe that can be used to characterize the orientation of collagen fibers in human dermis. A specific probing ability for collagen results from the use of second-harmonic-generation (SHG) light induced by collagen molecules in the tissue. Based on the concept of collagen SHG light, a reflection-type polarization measurement system (named SHG polarimetry) with a probe light spot of 15 microm in diameter has been constructed, and the human reticular dermis has been measured using this system. Resultant data exhibit that the reticular dermis possesses approximately uniaxial orientation of the collagen fibers. Furthermore, we demonstrated a nondestructive measurement of the collagen orientation in the papillary dermis across an epidermis layer. For distribution measurement of the collagen fiber orientation in the reticular dermis, we have extended the SHG polarimetry to one- (1-D) and two-dimensional (2-D) measurement. By the macroscopic 2-D SHG polarimetry, we have observed that the orientation angle and organization degree of collagen fibers vary widely depending on the discrete probing positions in the reticular dermis. Furthermore, microscopic 1-D SHG polarimetry indicated a swell of the orientation angle and a large variance of the organization degree in the collagen fibers in the microscopic region. These results imply that the reticular dermis posses a tangled structure of collagen fibers, which is highly consistent with the result of the anatomical examination of the skin. The proposed method will be a powerful tool for monitoring the microscopic distribution of the collagen fiber orientation in the human dermis.  (日)    [継承]
キーワード (推奨): 1. (英) Achilles Tendon (日) (読) [継承]
2. (英) Animals (日) (読) [継承]
3. (英) Cattle (日) (読) [継承]
4. (英) Cells, Cultured (日) (読) [継承]
5. (英) Collagen (日) (読) [継承]
6. (英) Dermis (日) (読) [継承]
7. (英) Humans (日) (読) [継承]
8. (英) Microscopy, Polarization (日) (読) [継承]
9. (英) Models, Theoretical (日) (読) [継承]
10. (英) Tissue Distribution (日) (読) [継承]
発行所 (推奨): SPIE The International Society for Optical Engineering [継承]
誌名 (必須): Journal of Biomedical Optics (Society of Photo-optical Instrumentation Engineers/International Biomedical Optics Society)
(pISSN: 1083-3668, eISSN: 1560-2281)

ISSN (任意): 1083-3668
ISSN: 1083-3668 (pISSN: 1083-3668, eISSN: 1560-2281)
Title: Journal of biomedical optics
Title(ISO): J Biomed Opt
Publisher: S P I E - International Society for Optical Engineering
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 9 [継承]
(必須): 2 [継承]
(必須): 259 264 [継承]
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年月日 (必須): 西暦 2004年 3月 初日 (平成 16年 3月 初日) [継承]
URL (任意):
DOI (任意): 10.1117/1.1644116    (→Scopusで検索) [継承]
PMID (任意): 15065889    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000220702200004 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Osaka University, Graduate School of Engineering Science, Toyonaka, Osaka, 560-8531 Japan. t-yasui@me.es.osaka-u.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]
4.(英) MedlineDate: 2004 Mar-Apr  (日)    [継承]

標準的な表示

和文冊子 ● Takeshi Yasui, Yoshiyuki Tohno and Tsutomu Araki : Characterization of collagen orientation in human dermis by two-dimensional second-harmonic-generation polarimetry, Journal of Biomedical Optics, Vol.9, No.2, 259-264, 2004.
欧文冊子 ● Takeshi Yasui, Yoshiyuki Tohno and Tsutomu Araki : Characterization of collagen orientation in human dermis by two-dimensional second-harmonic-generation polarimetry, Journal of Biomedical Optics, Vol.9, No.2, 259-264, 2004.

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