『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=213994)

EID=213994EID:213994, Map:0, LastModified:2018年5月23日(水) 17:08:21, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[細井 和雄], Read:継承, Write:継承, Delete:継承.
種別 (必須): 国際会議 [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.摂食機能制御学講座.口腔分子生理学 (2004年4月1日〜2015年3月31日) [継承]
著者 (必須): 1. (英) Wang, Chun (日) Wang, Chun (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Chen, Gang (日) Chen, Gang (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Jiang, Junkang (日) Jiang, Junkang (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Qiu, Lianglin (日) Qiu, Lianglin (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
5.細井 和雄
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学籍番号 (推奨):
[継承]
6.姚 陳娟 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔分子生理学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Aquaglyceroporins are involved in uptake of arsenite into murine gastrointestinal tissues  (日)    [継承]
副題 (任意):
要約 (任意): (英) Aquaglyceroporins (AQGPs) are members of aquaporin (AQP) family and belong to a subgroup of this water channel family; they are transmembrane proteins that transport water as well as glycerol and other solutes of small molecules. Recent studies have also identified that AQGPs are important transporters of trivalent metalloid in some mammalian cells. However, the uptake routes of arsenite in mammals are still less defined. In this study, to understand the routes of arsenite intake in mammals, mice were treated with Hg(II), glycerol, and As(III) and uptake of As(III) into the gastrointestinal tissues was measured. The level of inorganic arsenic (iAs) in gastrointestinal tissues after As(III) stimulation was much higher than Hg(II) +As(III) or glycerol+As(III) group. RT-PCR results showed that AQGPs were extensively expressed in gastrointestinal tissues of mice. We also treated Caco-2 cells with Hg(II) and As(III); the level of iAs in a group treated with Hg(II)+As(III) decreased compared with As(III)-treated group. Our results suggested that AQGPs could be important transporters in arsenite uptake into gastrointestinal tissues of mice, but more data are need to prove if AQGPs is the only pathway involved in As transport in mammals or just one of them.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Aquaglyceroporins (日) (読) [継承]
3. (英) Arsenites (日) (読) [継承]
4. (英) Biological Transport (日) (読) [継承]
5. (英) Cell Line (日) (読) [継承]
6. (英) Gastrointestinal Tract (日) (読) [継承]
7. (英) Glycerol (日) (読) [継承]
8. (英) Humans (日) (読) [継承]
9. (英) Male (日) (読) [継承]
10. (英) Mercury (日) (読) [継承]
11. (英) Mice (日) (読) [継承]
12. (英) Mice, Inbred ICR (日) (読) [継承]
13. (英) Signal Transduction (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1349-6867
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 56 [継承]
(必須): Suppl [継承]
(必須): 343 346 [継承]
都市 (必須): 徳島 (Tokushima/[日本国]) [継承]
年月日 (必須): 西暦 2009年 12月 初日 (平成 21年 12月 初日) [継承]
URL (任意):
DOI (任意): 10.2152/jmi.56.343    (→Scopusで検索) [継承]
PMID (任意): 20224220    (→Scopusで検索) [継承]
NAID (任意):
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Scopus (任意):
機関リポジトリ : 111458 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Chun Wang, Gang Chen, Junkang Jiang, Lianglin Qiu, Kazuo Hosoi and Chenjuan Yao : Aquaglyceroporins are involved in uptake of arsenite into murine gastrointestinal tissues, The Journal of Medical Investigation : JMI, Vol.56, No.Suppl, 343-346, Tokushima, Dec. 2009.
欧文冊子 ● Chun Wang, Gang Chen, Junkang Jiang, Lianglin Qiu, Kazuo Hosoi and Chenjuan Yao : Aquaglyceroporins are involved in uptake of arsenite into murine gastrointestinal tissues, The Journal of Medical Investigation : JMI, Vol.56, No.Suppl, 343-346, Tokushima, Dec. 2009.

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