| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Ogushi Yuji (日) (読)
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| 2. | (英) Akabane Gen (日) (読)
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| 3. | 長谷川 敬展 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔分子生理学])
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| 4. | (英) Mochida Hiroshi (日) (読)
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| 5. | (英) Matsuda Manabu (日) (読)
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| 6. | (英) Suzuki Masakazu (日) (読)
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| 7. | (英) Tanaka Shigeyasu (日) (読)
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| ○題名 (必須): | □ | (英) Water adaptation strategy in anuran amphibians: molecular diversity of aquaporin. (日)
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| ○要約 (任意): | □ | (英) Most adult anuran amphibians except for the aquatic species absorb water across the ventral pelvic skin and reabsorb it from urine in the urinary bladder. Many terrestrial and arboreal species use a region in the posterior or pelvic region of the ventral skin that is specialized for rapid rehydration from shallow water sources or moist substrates. Periods of terrestrial activity can be prolonged by reabsorption of dilute urine from the urinary bladder. Aquaporin (AQP), a water channel protein, plays a fundamental role in these water absorption/reabsorption processes, which are regulated by antidiuretic hormone. Characterization of AQPs from various anurans revealed that the unique water homeostasis is basically mediated by two types of anuran-specific AQPs, i.e. ventral pelvic skin and urinary bladder type, respectively. The bladder-type AQP is further expressed in the pelvic skin of terrestrial and arboreal species, together with the pelvic skin-type AQP. In contrast, the pelvic skin-type AQP (AQP-x3) of the aquatic Xenopus has lost the ability of efficient protein production. The extra C-terminal tail in AQP-x3 consisting of 33 nucleotides within the coding region appears to participate in the posttranscriptional regulation of AQP-x3 gene expression by attenuating protein expression. The positive transcriptional regulation of bladder-type AQP in the pelvic skin and negative posttranscriptional regulation of pelvic skin-type AQP provide flexibility in the water regulation mechanisms, which might have contributed to the evolutionary adaptation of anurans to a wide variety of water environments. (日)
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| ○キーワード (推奨): | 1. | (英) Adaptation, Biological (日) (読)
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| 2. | (英) Amino Acid Sequence (日) (読)
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| 3. | (英) Animals (日) (読)
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| 4. | (英) Anura (日) (読)
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| 5. | (英) Aquaporins (日) (読)
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| 6. | (英) Ecosystem (日) (読)
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| 7. | (英) Female (日) (読)
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| 8. | (英) Gene Expression Regulation (日) (読)
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| 9. | (英) Genetic Variation (日) (読)
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| 10. | (英) Male (日) (読)
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| 11. | (英) Molecular Sequence Data (日) (読)
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| 12. | (英) Sequence Homology, Amino Acid (日) (読)
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| 13. | (英) Species Specificity (日) (読)
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| 14. | (英) Urinary Bladder (日) (読)
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| 15. | (英) Water (日) (読)
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| 16. | (英) Water-Electrolyte Balance (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Endocrinology ([The Endocrine Society])
(pISSN: 0013-7227, eISSN: 1945-7170)
| ○ISSN (任意): | □ | 1945-7170
ISSN: 0013-7227
(pISSN: 0013-7227, eISSN: 1945-7170) Title: EndocrinologyTitle(ISO): EndocrinologyPublisher: Oxford University Press (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 151
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ | 165 173
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2009年 10月 23日 (平成 21年 10月 23日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1210/en.2009-0841 (→Scopusで検索)
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| ○PMID (任意): | □ | 19854867 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Integrated Bioscience Section, Graduate School of Science and Technology, Shizuoka University, Ohya 836, Suruga-ku, Shizuoka 422-8529, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Comparative Study (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 4. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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