『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Lee Byoung-Hee (日) (読)
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[継承]
2. (英) Yoshimatsu Kumiko (日) (読)
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[継承]
3. (英) Maeda Akihiko (日) (読)
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4.落合 和彦
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5. (英) Morimatsu Masami (日) (読)
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6. (英) Araki Koichi (日) (読)
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7. (英) Ogino Michiko (日) (読)
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8. (英) Morikawa Shigeru (日) (読)
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9. (英) Arikawa Jiro (日) (読)
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題名 (必須): (英) Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules.  (日)    [継承]
副題 (任意):
要約 (任意): (英) We performed yeast two-hybrid screening of a human kidney cell cDNA library to study the biological role of the hantavirus nucleocapsid protein (NP). We found that Seoul virus (SEOV) and Hantaan virus (HTNV) NPs were associated with small ubiquitin-like modifier (SUMO)-1-interacting proteins PIAS1, PIASxbeta, HIPK2, CHD3, and TTRAP, which interacted with the SUMO-1 conjugating enzyme (Ubc-9) and SUMO-1 in the yeast two-hybrid assay. Interactions between the HIPK2, CHD3, and TTRAP proteins and SEOV NP were also shown in a mammalian two-hybrid assay. However, there was no interaction between PIAS proteins and NP, which was probably due to the inhibitory effect of PIAS on transcription in the mammalian two-hybrid assay. Nevertheless, a co-expression experiment suggested the existence of a PIAS-NP interaction in the cytoplasm. The region spanning amino acids 100-125 of SEOV NP, which represents a critical region for NP-NP polymerization, was found to be responsible for the interaction with SUMO-1-related molecules in both the yeast and mammalian two-hybrid assays. These results add to the information on interactions of hantavirus NP and host cellular proteins.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Capsid Proteins (日) (読) [継承]
3. (英) Cell Line (日) (読) [継承]
4. (英) Cercopithecus aethiops (日) (読) [継承]
5. (英) Cytoplasm (日) (読) [継承]
6. (英) Gene Library (日) (読) [継承]
7. (英) Hantaan virus (日) (読) [継承]
8. (英) Hela Cells (日) (読) [継承]
9. (英) Humans (日) (読) [継承]
10. (英) Nucleocapsid Proteins (日) (読) [継承]
11. (英) Protein Inhibitors of Activated STAT (日) (読) [継承]
12. (英) Proteins (日) (読) [継承]
13. (英) SUMO-1 Protein (日) (読) [継承]
14. (英) Seoul virus (日) (読) [継承]
15. (英) Ubiquitin-Conjugating Enzymes (日) (読) [継承]
16. (英) Vero Cells (日) (読) [継承]
17. (英) Viral Core Proteins (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Virus Research ([Elsevier Science B.V.])
(pISSN: 0168-1702, eISSN: 1872-7492)

ISSN (任意): 0168-1702
ISSN: 0168-1702 (pISSN: 0168-1702, eISSN: 1872-7492)
Title: Virus research
Title(ISO): Virus Res
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 98 [継承]
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(必須): 83 91 [継承]
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年月日 (必須): 西暦 2003年 12月 初日 (平成 15年 12月 初日) [継承]
URL (任意):
DOI (任意): 10.1016/j.virusres.2003.09.001    (→Scopusで検索) [継承]
PMID (任意): 14609633    (→Scopusで検索) [継承]
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WOS (任意): 000186830600009 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Institute for Animal Experimentation, Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo 060-8638, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Byoung-Hee Lee, Kumiko Yoshimatsu, Akihiko Maeda, Kazuhiko Ochiai, Masami Morimatsu, Koichi Araki, Michiko Ogino, Shigeru Morikawa and Jiro Arikawa : Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules., Virus Research, Vol.98, No.1, 83-91, 2003.
欧文冊子 ● Byoung-Hee Lee, Kumiko Yoshimatsu, Akihiko Maeda, Kazuhiko Ochiai, Masami Morimatsu, Koichi Araki, Michiko Ogino, Shigeru Morikawa and Jiro Arikawa : Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules., Virus Research, Vol.98, No.1, 83-91, 2003.

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