『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=204563)

EID=204563EID:204563, Map:0, LastModified:2013年10月10日(木) 14:36:22, Operator:[松井 栄里], Avail:TRUE, Censor:0, Owner:[湯浅 恵造], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.生命情報工学 (2006年4月1日〜2016年3月31日) [継承]
著者 (必須): 1.湯浅 恵造 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.応用生命系.生体分子機能学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.応用生命講座])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Uehara Shotaro (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.長浜 正巳
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.辻 明彦
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Transcriptional regulation of cGMP-dependent protein kinase II (cGK-II) in chondrocytes.  (日)    [継承]
副題 (任意):
要約 (任意): (英) The C-type natriuretic peptide/natriuretic peptide receptor-B/cGMP pathway plays an important role in the regulation of endochondral ossification. In chondrocytes, the physiological effect of cGMP is mediated primarily by the activation of cGMP-dependent protein kinase II (cGK-II). In this study, we investigated the transcriptional regulation of cGK-II in chondrocytes. The expression pattern of cGK-II transcripts was examined during chondrogenic differentiation of ATDC5 cells. cGK-II mRNA was not detectable in undifferentiated cells, but increased dramatically prior to differentiation to the hypertrophic stage. To analyze the transcriptional regulation of cGK-II, the 5'-flanking region of the mouse cGK-II gene was isolated and characterized. The promoter activity of the cGK-II gene decreased markedly following deletion and mutagenesis of the putative Nkx-binding site between nucleotide positions -292 and -286. These results suggest that the homeobox gene Nkx family is critical for the transcriptional regulation of cGK-II during chondrogenesis.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Base Sequence (日) (読) [継承]
3. (英) Cartilage (日) (読) [継承]
4. (英) Cell Differentiation (日) (読) [継承]
5. (英) Cell Line, Tumor (日) (読) [継承]
6. (英) Chondrocytes (日) (読) [継承]
7. (英) Chondrogenesis (日) (読) [継承]
8. (英) Cyclic GMP-Dependent Protein Kinases (日) (読) [継承]
9. (英) Gene Expression Regulation, Enzymologic (日) (読) [継承]
10. (英) Mice (日) (読) [継承]
11. (英) Molecular Sequence Data (日) (読) [継承]
12. (英) Promoter Regions, Genetic (日) (読) [継承]
13. (英) Rats (日) (読) [継承]
14. (英) Transcription, Genetic (日) (読) [継承]
発行所 (推奨): (英) Japan Society for Bioscience, Biotechnology, and Agrochemistry (日) 公益社団法人 日本農芸化学会 (読) [継承]
誌名 (必須): Bioscience, Biotechnology, and Biochemistry ([社団法人 日本農芸化学会])
(pISSN: 0916-8451, eISSN: 1347-6947)

ISSN (任意): 1347-6947
ISSN: 0916-8451 (pISSN: 0916-8451, eISSN: 1347-6947)
Title: Bioscience, biotechnology, and biochemistry
Title(ISO): Biosci. Biotechnol. Biochem.
Supplier: 社団法人日本農芸化学会
Publisher: Taylor & Francis
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 74 [継承]
(必須): 1 [継承]
(必須): 44 49 [継承]
都市 (任意):
年月日 (必須): 西暦 2010年 1月 7日 (平成 22年 1月 7日) [継承]
URL (任意): http://ci.nii.ac.jp/naid/10027549958/ [継承]
DOI (任意): 10.1271/bbb.90529    (→Scopusで検索) [継承]
PMID (任意): 20057151    (→Scopusで検索) [継承]
NAID (任意): 10027549958 [継承]
WOS (任意): 000274102300008 [継承]
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Biological Science and Technology, The University of Tokushima Graduate School, Japan. yuasa@bio.tokushima-u.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Keizo Yuasa, Shotaro Uehara, Masami Nagahama and Akihiko Tsuji : Transcriptional regulation of cGMP-dependent protein kinase II (cGK-II) in chondrocytes., Bioscience, Biotechnology, and Biochemistry, Vol.74, No.1, 44-49, 2010.
欧文冊子 ● Keizo Yuasa, Shotaro Uehara, Masami Nagahama and Akihiko Tsuji : Transcriptional regulation of cGMP-dependent protein kinase II (cGK-II) in chondrocytes., Bioscience, Biotechnology, and Biochemistry, Vol.74, No.1, 44-49, 2010.

関連情報

Number of session users = 0, LA = 0.41, Max(EID) = 363197, Max(EOID) = 972185.