『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=203921EID:203921, Map:0, LastModified:2018年5月23日(水) 17:08:14, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[中川 弘], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨): 研究 [継承]
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著者 (必須): 1.中川 弘 ([徳島大学.病院.診療科.小児歯科])
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2.樋浦 明夫
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3.三留 雅人
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4.石村 和敬
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題名 (必須): (英) Nerve fibers that were not stained with the non-specific acetylcholinesterase (NsAchE) method, and TRPV1- and IB4-positive nerve fibers in the rat cornea.(Cited in "Journal of Chemical Neuroanatomy, 01/2014")  (日)    [継承]
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要約 (任意): (英) Previously, we noticed the presence of nerve fiber-like structures in a whole mount preparation of the rat cornea that had not been stained with the non-specific acetylcholinesterase (NsAchE) method. These nerve-like fibers were projected into the central area of the cornea, forming a mesh-like pattern. The aim of this study is to examine the properties of these mesh-like fibers using the following two methods: their sensitivity to capsaicin and the detection of isolectin B4 (IB4)- and capsaicin receptor TRPV1 (transient receptor potential vanilloid 1)-reactivities. The mean disappeared area of non-stained fibers after NsAchE treatment was 26% of the total areas in the neonatally capsaicin-treated cornea. Bunches composed of fine IB4-positive nerve fibers were seen in a whole mount preparation. There were connections between the bunches, producing a mesh-like pattern similar to that of the fibers that were not stained with NsAchE. Fine TRPV1-immunoreactive (ir) nerve fibers were also shown to form bunches, with connections between each bunch observed in whole mount preparations. Thus, TRPV1-ir nerve fibers seem to densely innervate the rat corneal subepithelial stroma and are distinct from the NsAchE-positive nerve fibers. The TRPV1-ir fine nerve fibers overlapped with the IB4-positive nerve fibers, suggesting that the mesh-like fibers that were not stained with NsAchE are fine nociceptive sensory nerve fibers because of their sensitivity to capsaicin and similar distribution pattern to IB4- and TRPV1-positive nerve fibers.  (日)    [継承]
キーワード (推奨): 1. (英) TRPV1 (日) (読) [継承]
2. (英) IB4 (日) (読) [継承]
3. (英) Nociceptive sensory nerve fibers (日) (読) [継承]
4.角膜 (cornea) [継承]
5.カプサイシン (capsaicin) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1349-6867
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2009年 8月 末日 (平成 21年 8月 末日) [継承]
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DOI (任意): 10.2152/jmi.56.157    (→Scopusで検索) [継承]
PMID (任意): 19763029    (→Scopusで検索) [継承]
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機関リポジトリ : 111323 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Pediatric Dentistry, Tokushima University Hospital, Tokushima , Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Hiroshi Nakagawa, Akio Hiura, Masato Mitome and Kazunori Ishimura : Nerve fibers that were not stained with the non-specific acetylcholinesterase (NsAchE) method, and TRPV1- and IB4-positive nerve fibers in the rat cornea.(Cited in "Journal of Chemical Neuroanatomy, 01/2014"), The Journal of Medical Investigation : JMI, Vol.56, No.3,4, 157-165, 2009.
欧文冊子 ● Hiroshi Nakagawa, Akio Hiura, Masato Mitome and Kazunori Ishimura : Nerve fibers that were not stained with the non-specific acetylcholinesterase (NsAchE) method, and TRPV1- and IB4-positive nerve fibers in the rat cornea.(Cited in "Journal of Chemical Neuroanatomy, 01/2014"), The Journal of Medical Investigation : JMI, Vol.56, No.3,4, 157-165, 2009.

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