| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Kheirvari Sorayya (日) (読)
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| ○学籍番号 (推奨): |
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| 2. | 上江洲 香代子
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| 3. | 山本 茂
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| 4. | 中屋 豊
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| ○題名 (必須): | □ | (英) High-dose dietary supplementation of vitamin A induces brain-derived neurotrophic factor and nerve growth factor production in mice with simultaneous deficiency of vitamin A and zinc. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Marginal vitamin A and zinc (Zn) deficiency often co-exist in many populations. Vitamin A plays a trophic role in brain and is important for its development. We investigated effects of dietary supplementation of vitamin A on brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) production in mice depleted for vitamin A and Zn. After 3 months' feeding with a low vitamin A and Zn (LVA-LZ) diet, mice were divided into two groups and replenished with either normal or high vitamin A with low Zn diet for an additional 2 months. Levels of BDNF and NGF were measured from extracts of hippocampus, cortex and cerebellum at the end of the third and fifth months. The LVA-LZ group tended to show decreased amounts of the BDNF and NGF, while animals supplemented with high vitamin A along with Zn deficiency had high BDNF and NGF concentrations. From these results, we conclude that vitamin A may increase BDNF and NGF levels. (日)
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| ○キーワード (推奨): | 1. | (英) Animals (日) (読)
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| 2. | (英) Brain-Derived Neurotrophic Factor (日) (読)
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| 3. | 小脳 (cerebellum)
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| 4. | (英) Cerebral Cortex (日) (読)
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| 5. | (英) Diet (日) (読)
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| 6. | (英) Dietary Supplements (日) (読)
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| 7. | (英) Hippocampus (日) (読)
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| 8. | (英) Male (日) (読)
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| 9. | (英) Mice (日) (読)
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| 10. | (英) Nerve Growth Factor (日) (読)
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| 11. | (英) Specific Pathogen-Free Organisms (日) (読)
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| 12. | ビタミンA (vitamin A)
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| 13. | (英) Vitamin A Deficiency (日) (読)
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| 14. | 亜鉛 (zinc)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Nutritional Neuroscience (Maney Publishing)
(pISSN: 1028-415X, eISSN: 1476-8305)
| ○ISSN (任意): | □ | 1476-8305
ISSN: 1028-415X
(pISSN: 1028-415X, eISSN: 1476-8305) Title: Nutritional neuroscienceTitle(ISO): Nutr NeurosciPublisher: Maney Publishing (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 11
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| ○号 (必須): | □ | 5
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| ○頁 (必須): | □ | 228 234
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2008年 10月 初日 (平成 20年 10月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1179/147683008X301603 (→Scopusで検索)
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| ○PMID (任意): | □ | 18782483 (→Scopusで検索)
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| ○CRID (任意): |
| ○Scopus (任意): | 1. | 2-s2.0-56349171225
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Nutrition and Metabolism, University of Tokushima Graduate School, Tokushima, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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