『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=189892)

EID=189892EID:189892, Map:0, LastModified:2012年10月9日(火) 22:04:00, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[佐々木 卓也], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.西村 範行
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Araki Kunihiko (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Shinahara Wakako (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Nakano Yumiko (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Nishimura Kaho (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
6.東尾 浩典
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
7.佐々木 卓也 ([徳島大学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Rab3 subfamily small G proteins (Rab3A, Rab3B, Rab3C, and Rab3D) control the regulated exocytosis in neuronal/secretory cells. Rab3B is also detected and upregulated in non-neuronal/non-secretory cells, whereas its function remains elusive. In the present study, we identified growth-arrest-specific gene 8 (Gas8), an evolutionally conserved microtubule-binding protein that is upregulated in growth-arrested NIH 3T3 cells and involved in the dynein motor regulation in flagellar/ciliary axoneme, as a novel Rab3B-binding protein using a yeast two-hybrid system. Rab3B as well as Gas8 was upregulated in growth-arrested NIH 3T3 cells and enriched in testis and lung with well-developed flagella/cilia. Gas8 was specifically interacted with the GTP-bound form of Rab3B and co-localized with Rab3B at the Golgi in NIH 3T3 cells. Furthermore, Rab3B was relocated upon expression of the Rab3B-binding domain of Gas8. These results suggest that Gas8 links Rab3B to microtubules in NIH 3T3 cells.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Blotting, Western (日) (読) [継承]
3. (英) Cricetinae (日) (読) [継承]
4. (英) Immunoprecipitation (日) (読) [継承]
5. (英) Mice (日) (読) [継承]
6. (英) Microscopy, Fluorescence (日) (読) [継承]
7. (英) NIH 3T3 Cells (日) (読) [継承]
8. (英) Protein Binding (日) (読) [継承]
9. (英) Proteins (日) (読) [継承]
10. (英) Reverse Transcriptase Polymerase Chain Reaction (日) (読) [継承]
11. (英) Two-Hybrid System Techniques (日) (読) [継承]
12. (英) rab3 GTP-Binding Proteins (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Archives of Biochemistry and Biophysics ([Elsevier])
(pISSN: 0003-9861, eISSN: 1096-0384)

ISSN (任意): 1096-0384
ISSN: 0003-9861 (pISSN: 0003-9861, eISSN: 1096-0384)
Title: Archives of biochemistry and biophysics
Title(ISO): Arch Biochem Biophys
Publisher: Elsevier Inc.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 474 [継承]
(必須): 1 [継承]
(必須): 136 142 [継承]
都市 (任意):
年月日 (必須): 西暦 2008年 6月 1日 (平成 20年 6月 1日) [継承]
URL (任意):
DOI (任意): 10.1016/j.abb.2008.03.032    (→Scopusで検索) [継承]
PMID (任意): 18396146    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Biochemistry, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Noriyuki Nishimura, Kunihiko Araki, Wakako Shinahara, Yumiko Nakano, Kaho Nishimura, Hironori Higashio and Takuya Sasaki : Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells., Archives of Biochemistry and Biophysics, Vol.474, No.1, 136-142, 2008.
欧文冊子 ● Noriyuki Nishimura, Kunihiko Araki, Wakako Shinahara, Yumiko Nakano, Kaho Nishimura, Hironori Higashio and Takuya Sasaki : Interaction of Rab3B with microtubule-binding protein Gas8 in NIH 3T3 cells., Archives of Biochemistry and Biophysics, Vol.474, No.1, 136-142, 2008.

関連情報

Number of session users = 5, LA = 0.85, Max(EID) = 376567, Max(EOID) = 1008469.