『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=187869)

EID=187869EID:187869, Map:0, LastModified:2012年10月13日(土) 17:15:06, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[佐藤 陽一], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Kirino Yasushi (日) (読)
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2. (英) Kamimoto Takayuki (日) (読)
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3.佐藤 陽一 ([徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.生命薬学系.医薬品情報学])
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4.川添 和義
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5.水口 和生
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6.中堀 豊
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題名 (必須): (英) Increased Plasma Dipeptidyl Peptidase IV (DPP IV) Activity and Decreased DPP IV Activity of Visceral But Not Subcutaneous Adipose Tissue in Impaired Glucose Tolerance Rats Induced by High-Fat or High-Sucrose Diet  (日)    [継承]
副題 (任意):
要約 (任意): (英) Several studies have investigated whether dipeptidyl peptidase IV (DPP IV) activity is correlated to the severity of diabetes; however, it remains unclear. To investigate the roles of DPP IV activity in metabolic abnormalities, impaired glucose tolerance rats were produced using a high-fat (HF) or high-sucrose (HS) diet. HF diet-fed rats obviously exhibited impaired glucose tolerance, with increases in subcutaneous and epididymal fat mass, insulin resistance and dyslipidaemia. In rats fed a HS diet rather than a normal diet, lower body weight and fasting blood glucose were observed temporarily in the early period after HS diet feeding; however, impaired glucose tolerance was evoked to some extent with an increase in epididymal fat mass. Both HF and HS diet-fed rats showed significantly higher plasma DPP IV activity than normal diet-fed rats, in the order of HF diet>HS diet>normal diet. HF and HS diets did not significantly affect DPP IV activity and mRNA expression in the kidney. On the other hand, HF, but not HS, diet caused a significant decrease in DPP IV activity in the liver as compared to the control. Of note, both HF and HS diets caused a significant decrease in DPP IV activity in epididymal fat, even though they did not change DPP IV activity in subcutaneous fat. In conclusion, HF or HS diet-induced impaired glucose tolerance with visceral fat accumulation may be interrelated with increased plasma DPP IV activity and decreased DPP IV activity of visceral but not subcutaneous adipose tissue.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Body Weight (日) (読) [継承]
3. (英) Dietary Fats (日) (読) [継承]
4. (英) Dietary Sucrose (日) (読) [継承]
5. (英) Dipeptidyl Peptidase 4 (日) (読) [継承]
6. (英) Eating (日) (読) [継承]
7. (英) Glucose Intolerance (日) (読) [継承]
8. (英) Glucose Tolerance Test (日) (読) [継承]
9. (英) Intra-Abdominal Fat (日) (読) [継承]
10. (英) Male (日) (読) [継承]
11. (英) Organ Specificity (日) (読) [継承]
12. (英) RNA (日) (読) [継承]
13. (英) Rats (日) (読) [継承]
14. (英) Rats, Inbred F344 (日) (読) [継承]
15. (英) Subcutaneous Fat (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Biological & Pharmaceutical Bulletin ([日本薬学会])
(pISSN: 0918-6158, eISSN: 1347-5215)

ISSN (任意): 0918-6158
ISSN: 0918-6158 (pISSN: 0918-6158, eISSN: 1347-5215)
Title: Biological & pharmaceutical bulletin
Title(ISO): Biol Pharm Bull
Supplier: 公益社団法人日本薬学会
Publisher: Pharmaceutical Society of Japan
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2009年 3月 初日 (平成 21年 3月 初日) [継承]
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DOI (任意): 10.1248/bpb.32.463    (→Scopusで検索) [継承]
PMID (任意): 19252296    (→Scopusで検索) [継承]
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WOS (任意): 000263777800027 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Human Genetics and Public Health, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Yasushi Kirino, Takayuki Kamimoto, Youichi Sato, Kazuyoshi Kawazoe, Kazuo Minakuchi and Yutaka Nakahori : Increased Plasma Dipeptidyl Peptidase IV (DPP IV) Activity and Decreased DPP IV Activity of Visceral But Not Subcutaneous Adipose Tissue in Impaired Glucose Tolerance Rats Induced by High-Fat or High-Sucrose Diet, Biological & Pharmaceutical Bulletin, Vol.32, No.3, 463-467, 2009.
欧文冊子 ● Yasushi Kirino, Takayuki Kamimoto, Youichi Sato, Kazuyoshi Kawazoe, Kazuo Minakuchi and Yutaka Nakahori : Increased Plasma Dipeptidyl Peptidase IV (DPP IV) Activity and Decreased DPP IV Activity of Visceral But Not Subcutaneous Adipose Tissue in Impaired Glucose Tolerance Rats Induced by High-Fat or High-Sucrose Diet, Biological & Pharmaceutical Bulletin, Vol.32, No.3, 463-467, 2009.

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