『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=185435EID:185435, Map:0, LastModified:2013年5月19日(日) 19:01:44, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[佐藤 陽一], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Yan Hong-Tao (日) (読)
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2.新家 利一
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3.佐藤 陽一 ([徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.生命薬学系.医薬品情報学])
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4. (英) Yang Xin-Jun (日) (読)
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5. (英) Chen Gang (日) (読)
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6. (英) Sakamoto Kozue (日) (読)
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7. (英) Kinoshita Keigo (日) (読)
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8. (英) Aburatani Hiroyuki (日) (読)
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9.中堀 豊
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題名 (必須): (英) Overexpression of SOX15 Inhibits Proliferation of NT2/D1 Cells Derived from a Testicular Embryonal Cell Carcinoma  (日)    [継承]
副題 (任意):
要約 (任意): (英) SOX (Sry-related HMG box) family proteins, which have an evolutionarily conserved DNA binding domain, have crucial roles in cell differentiation. However, their target genes remain enigmatic. Some members of the SOX family may have roles in regulation of cell proliferation. We established stable NT2/D1 cell lines overexpressing SOX15 (SOX15-NT2/D1), and a modified 3-(4,5-dime-thylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed that the SOX15-NT2/D1 cells exhibited significantly slower growth than the controls. Flow cytometry analysis revealed that an increased fraction of the SOX15-NT2/D1 cells were in G1-G0. In addition, a microarray analysis identified 26 genes that were up-regulated in the SOX15-NT2/D1 cells, but none that were down-regulated genes. Among the up-regulated genes, IGFBP5, S100A4, ID2, FABP5, MTSS1, PDCD4 have been shown to be related to cell proliferation and/or the cell cycle.  (日)    [継承]
キーワード (推奨): 1. (英) Carcinoma, Embryonal (日) (読) [継承]
2. (英) Cell Line, Tumor (日) (読) [継承]
3. (英) Cell Proliferation (日) (読) [継承]
4. (英) DNA-Binding Proteins (日) (読) [継承]
5. (英) Flow Cytometry (日) (読) [継承]
6. (英) Gene Expression (日) (読) [継承]
7. (英) High Mobility Group Proteins (日) (読) [継承]
8. (英) Humans (日) (読) [継承]
9. (英) Male (日) (読) [継承]
10. (英) Oligonucleotide Array Sequence Analysis (日) (読) [継承]
11. (英) RNA, Messenger (日) (読) [継承]
12. (英) Reverse Transcriptase Polymerase Chain Reaction (日) (読) [継承]
13. (英) SOX Transcription Factors (日) (読) [継承]
14. (英) Testicular Neoplasms (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Molecules and Cells (Korean Society for Molecular and Cellular Biology)
(pISSN: 1016-8478, eISSN: 0219-1032)

ISSN (任意): 1016-8478
ISSN: 1016-8478 (pISSN: 1016-8478, eISSN: 0219-1032)
Title: Molecules and cells
Title(ISO): Mol Cells
Publisher: Korean Society for Molecular and Cellular Biology, co-published with Springer
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 24 [継承]
(必須): 3 [継承]
(必須): 323 328 [継承]
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年月日 (必須): 西暦 2007年 12月 31日 (平成 19年 12月 31日) [継承]
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DOI (任意):
PMID (任意): 18182846    (→Scopusで検索) [継承]
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WOS (任意): 000252248000003 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Human Genetics and Public Health, Faculty of Medicine, Graduate School of Proteomics, The University of Tokushima, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Hong-Tao Yan, Toshikatsu Shinka, Youichi Sato, Xin-Jun Yang, Gang Chen, Kozue Sakamoto, Keigo Kinoshita, Hiroyuki Aburatani and Yutaka Nakahori : Overexpression of SOX15 Inhibits Proliferation of NT2/D1 Cells Derived from a Testicular Embryonal Cell Carcinoma, Molecules and Cells, Vol.24, No.3, 323-328, 2007.
欧文冊子 ● Hong-Tao Yan, Toshikatsu Shinka, Youichi Sato, Xin-Jun Yang, Gang Chen, Kozue Sakamoto, Keigo Kinoshita, Hiroyuki Aburatani and Yutaka Nakahori : Overexpression of SOX15 Inhibits Proliferation of NT2/D1 Cells Derived from a Testicular Embryonal Cell Carcinoma, Molecules and Cells, Vol.24, No.3, 323-328, 2007.

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