『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=178627)

EID=178627EID:178627, Map:0, LastModified:2012年10月9日(火) 20:36:30, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[細井 和雄], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.摂食機能制御学講座 (2004年4月1日〜2015年3月31日) [継承]
著者 (必須): 1. (英) Kurabuchi, Shingo (日) 倉淵, 眞悟 (読) くらぶち しんご
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Gresik, W, Edward (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.姚 陳娟 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔分子生理学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.細井 和雄
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Hypophysectomy and hormonal therapy modulate mK1-immunoreactive duct cells in the mice sublingual glands  (日)    [継承]
副題 (任意):
要約 (任意): (英) The immunocytochemical localization of a true tissue kallikrein, mK1, in mouse sublingual glands (SLGs) was examined following hypophysectomy and hormonal replacement therapy. In the glands of intact mice (14 weeks of age), mK1 was detected in the striated ducts (SDs). Full-fledged granular cells were scattered in the SDs of male mice (but not in those of female mice), showing a cellular mosaic distribution of mK1 with some being positive and others being negative. mK1 was also detected in transitional-type granular cells, though the secretory granules were too small and scarce to be visible by a light microscopy. Hypophysectomy in male mice resulted in the atrophy and loss of secretory granules in many SD cells. Granulation recovered after the repeated injection of 5alpha-dihydrotestosterone (DHT), 3,5,3'-triiodo-L: thyronine (T3), and dexamethasone (Dex), given either alone or in combination to the hypophysectomized mice. The concomitant injection of DHT and T3, with or without Dex, resulted in the reappearance of the full-fledged granular cells, only some of which were mK1-positive. Electron microscopy revealed mK1 to be present exclusively in the secretory granules of these mK1-positive cells, and no ultrastructural differences were observed between mK1-positive and mK1-negative full-fledged granular cells. These results show that the differentiation of the granular cell phenotype in the mouse SLG duct system requires the concomitant action of androgen and thyroid hormone and retards mK1 synthesis.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Dexamethasone (日) (読) [継承]
3. (英) Dihydrotestosterone (日) (読) [継承]
4. (英) Female (日) (読) [継承]
5. (英) Glucocorticoids (日) (読) [継承]
6. (英) Hormone Replacement Therapy (日) (読) [継承]
7. (英) Hypophysectomy (日) (読) [継承]
8. (英) Male (日) (読) [継承]
9. (英) Mice (日) (読) [継承]
10. (英) Mice, Inbred ICR (日) (読) [継承]
11. (英) Secretory Vesicles (日) (読) [継承]
12. (英) Sex Characteristics (日) (読) [継承]
13. (英) Sublingual Gland (日) (読) [継承]
14. (英) Tissue Kallikreins (日) (読) [継承]
15. (英) Triiodothyronine (日) (読) [継承]
発行所 (推奨): Springer-Verlag [継承]
誌名 (必須): Journal of Molecular Histology ([Springer-Verlag])
(pISSN: 1567-2379, eISSN: 1567-2387)

ISSN (任意): 1567-2379
ISSN: 1567-2379 (pISSN: 1567-2379, eISSN: 1567-2387)
Title: Journal of molecular histology
Title(ISO): J Mol Histol
Supplier: Kluwer Online
Publisher: Springer Netherlands
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 39 [継承]
(必須): 5 [継承]
(必須): 499 507 [継承]
都市 (任意):
年月日 (必須): 西暦 2008年 8月 22日 (平成 20年 8月 22日) [継承]
URL (任意):
DOI (任意): 10.1007/s10735-008-9189-7    (→Scopusで検索) [継承]
PMID (任意): 18716886    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Histology, The Nippon Dental University School of Life Dentistry, Tokyo, 102-8159, Japan. kurab-fm@tky.ndu.ac.jp  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Shingo Kurabuchi, Edward W Gresik, Chenjuan Yao and Kazuo Hosoi : Hypophysectomy and hormonal therapy modulate mK1-immunoreactive duct cells in the mice sublingual glands, Journal of Molecular Histology, Vol.39, No.5, 499-507, 2008.
欧文冊子 ● Shingo Kurabuchi, Edward W Gresik, Chenjuan Yao and Kazuo Hosoi : Hypophysectomy and hormonal therapy modulate mK1-immunoreactive duct cells in the mice sublingual glands, Journal of Molecular Histology, Vol.39, No.5, 499-507, 2008.

関連情報

Number of session users = 1, LA = 0.53, Max(EID) = 377721, Max(EOID) = 1010854.