『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=174124)

EID=174124EID:174124, Map:0, LastModified:2012年9月18日(火) 16:12:53, Operator:[三木 ちひろ], Avail:TRUE, Censor:0, Owner:[野地 澄晴], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.大学院ソシオテクノサイエンス研究部.ライフシステム部門 (2006年4月1日〜) [継承]
著者 (必須): 1. (英) Okamoto Mayumi (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.友成 さゆり ([徳島大学.技術支援部.常三島技術部門])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Naito Yuki (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Saigo Kaoru (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
5.野地 澄晴 ([徳島大学])
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貢献度 (任意):
学籍番号 (推奨):
[継承]
6. (英) Ui-Tei Kumiko (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
7.大内 淑代
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Introduction of silencing-inducing transgene against Fgf19 does not affect expression of Tbx5 and beta3-tubulin in the developing chicken retina.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Fgf19 is known to be expressed in the developing chicken eye but its functions during retinal development have remained elusive. Since Fgf19 is expressed in the dorsal portion of the optic cup, it is intriguing to know whether FGF19 is required for expression of dorso-ventral morphogenetic genes in the eye. To clarify this, expression patterns of Tbx5 and Vax were examined in the developing eye after in ovo RNA interference targeted against Fgf19. Quantitative polymerase chain reaction (PCR) analysis showed that the short-hairpin RNAs (shRNAs) targeted against Fgf19 could reduce its expression in the eye to less than 50% of a relative amount of mRNA, compared with contralateral or untreated control eyes. However, no obvious alteration in expression domains of Tbx5 or Vax was observed. Misexpression of Tbx5 or Tbx5-RNAi did not alter the Fgf19 expression either. Furthermore, although Fgf19 is expressed in the central retina before neurogenesis occurs, beta3-tubulin, a marker for early retinal differentiation was still detected in the central retina after knockdown of Fgf19. Thus, knockdown of Fgf19 supports no obvious regulations between Fgf19 and Tbx5, or exhibits no phenotypes that perturb early retinal differentiation.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Cells, Cultured (日) (読) [継承]
3. (英) Chick Embryo (日) (読) [継承]
4. (英) Electroporation (日) (読) [継承]
5. (英) Eye Proteins (日) (読) [継承]
6. (英) Fibroblast Growth Factors (日) (読) [継承]
7. (英) Gene Expression Regulation, Developmental (日) (読) [継承]
8. (英) Morphogenesis (日) (読) [継承]
9. (英) Polymerase Chain Reaction (日) (読) [継承]
10. (英) RNA Interference (日) (読) [継承]
11. (英) RNA, Messenger (日) (読) [継承]
12. (英) RNA, Small Interfering (日) (読) [継承]
13. (英) Retina (日) (読) [継承]
14. (英) T-Box Domain Proteins (日) (読) [継承]
15. (英) Transgenes (日) (読) [継承]
16. (英) Tubulin (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Development Growth & Differentiation ([日本発生生物学会])
(pISSN: 0012-1592, eISSN: 1440-169X)

ISSN (任意): 1440-169X
ISSN: 0012-1592 (pISSN: 0012-1592, eISSN: 1440-169X)
Title: Development, growth & differentiation
Title(ISO): Dev Growth Differ
Supplier: Japanese Society of Developmental Biologists
Publisher: Wiley Publishing
 (NLM Catalog  (医中誌Web  (Wiley  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
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(必須): 50 [継承]
(必須): 3 [継承]
(必須): 159 168 [継承]
都市 (任意):
年月日 (必須): 西暦 2008年 3月 初日 (平成 20年 3月 初日) [継承]
URL (任意):
DOI (任意): 10.1111/j.1440-169X.2008.00996.x    (→Scopusで検索) [継承]
PMID (任意): 18312426    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Life Systems, Institute of Technology and Science, The University of Tokushima, 2-1 Minami-Josanjima-cho, Tokushima City 770-8506, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Mayumi Okamoto, Sayuri Tomonari, Yuki Naito, Kaoru Saigo, Sumihare Noji, Kumiko Ui-Tei and Hideyo Ohuchi : Introduction of silencing-inducing transgene against Fgf19 does not affect expression of Tbx5 and beta3-tubulin in the developing chicken retina., Development Growth & Differentiation, Vol.50, No.3, 159-168, 2008.
欧文冊子 ● Mayumi Okamoto, Sayuri Tomonari, Yuki Naito, Kaoru Saigo, Sumihare Noji, Kumiko Ui-Tei and Hideyo Ohuchi : Introduction of silencing-inducing transgene against Fgf19 does not affect expression of Tbx5 and beta3-tubulin in the developing chicken retina., Development Growth & Differentiation, Vol.50, No.3, 159-168, 2008.

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