『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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○種別 (必須): □学術論文 (審査論文) [継承]
○言語 (必須): □英語 [継承]
○招待 (推奨):
○審査 (推奨): □Peer Review [継承]
○カテゴリ (推奨):
○共著種別 (推奨):
○学究種別 (推奨):
○組織 (推奨):
○著者 (必須): 1. (英) Sato T (日) (読)
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○学籍番号 (推奨):
[継承]
2. (英) Kawabata Y (日) (読)
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[継承]
3. (英) Nitta T (日) (読)
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[継承]
4. (英) Saigo Y (日) (読)
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[継承]
5. (英) Iwashita Y (日) (読)
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[継承]
6. (英) Suenaga S (日) (読)
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7. (英) Hamahira S (日) (読)
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8. (英) Indo H (日) (読)
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9.森田 康彦
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10. (英) Majima J. H (日) (読)
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11. (英) Sugihara K (日) (読)
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○題名 (必須): □(英) Expression of permeability-glycoprotein(p-gp) and uptake of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile(99Tcm-MIBI)in malignant tumour of the head and neck  (日)    [継承]
○副題 (任意):
○要約 (任意): □(英) The purpose of this study is to estimate the role of permeability-glycoprotein (P-gp) in the technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile (99Tc(m)-MIBI) scintigraphy. 71 patients with squamous cell carcinoma (39 patients with well differentiated, 19 with moderately differentiated and 13 with poorly differentiated tumour) were examined. Eighteen of these patients underwent 99Tc(m)-MIBI scintigraphy (early and delayed scans). The tumour retention index, obtained from the ratio of the accumulation of the delayed scan to that of the early scan, was divided into three groups. The immunohistochemical evaluation of P-gp expression was performed in all 71 patients. Levels of the P-gp expression were classified into three grades (score 0, 1 and 2). Correlations among the tumour retention index, the P-gp expression and the tumour tissue differentiation were evaluated. 17 of 18 patients showed a decreasing of the tumour retention index ranging from 0.70 to 0.93 (mean+/-SD=0.850+/-0.071). The tumour retention index showed a statistical correlation with the P-gp expression and the tumour tissue differentiation (chi-squared=7.802>7.779, P=0.10 and 16.835>14.860, P=0.005, respectively). Moreover, there was a statistical correlation between the P-gp expression and the tumour tissue differentiation (chi-squared=14.863>14.860, P=0.005). There is a possibility that the P-gp expression is high in the high-grade malignant tumours and P-gp causes the decrease of tumour retention index.  (日)    [継承]
○キーワード (推奨): 1. (英) Aged (日) (読) [継承]
2. (英) Carcinoma, Squamous Cell (日) (読) [継承]
3.細胞分化 (cell differentiation) [継承]
4.女性 (female) [継承]
5. (英) Head and Neck Neoplasms (日) (読) [継承]
6. (英) Humans (日) (読) [継承]
7.免疫組織化学 (immunohistochemistry) [継承]
8.男性 (male) [継承]
9. (英) P-Glycoprotein (日) (読) [継承]
10. (英) Radiopharmaceuticals (日) (読) [継承]
11. (英) Technetium Tc 99m Sestamibi (日) (読) [継承]
12. (英) Time Factors (日) (読) [継承]
○発行所 (推奨):
○誌名 (必須): □Dento Maxillo Facial Radiology (International Association of Maxillofacial Radiology/British Institute of Radiology)
(pISSN: 0250-832X, eISSN: 1476-542X)

○ISSN (任意): □0250-832X
ISSN: 0250-832X (pISSN: 0250-832X, eISSN: 1476-542X)
Title: Dento maxillo facial radiology
Title(ISO): Dentomaxillofac Radiol
Supplier: British Institute of Radiology
Publisher: British Institute of Radiology
 (NLM Catalog)   (Wiley)   (Scopus)   (CrossRef)  (Scopus information is found. [need login])
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○巻 (必須): □34 [継承]
○号 (必須): □5 [継承]
○頁 (必須): □274 278 [継承]
○都市 (任意):
○年月日 (必須): □西暦 2005年 9月 初日 (平成 17年 9月 初日) [継承]
○URL (任意):
○DOI (任意): □10.1259/dmfr/74230043    (→Scopusで検索) [継承]
○PMID (任意): □16120876    (→Scopusで検索) [継承]
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○Scopus (任意): □2-s2.0-24944545155 [継承]
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○備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Case Reports  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● T Sato, Y Kawabata, T Nitta, Y Saigo, Y Iwashita, S Suenaga, S Hamahira, H Indo, Yasuhiko Morita, H J. Majima and K Sugihara : Expression of permeability-glycoprotein(p-gp) and uptake of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile(99Tcm-MIBI)in malignant tumour of the head and neck, Dento Maxillo Facial Radiology, Vol.34, No.5, 274-278, 2005.
欧文冊子 ● T Sato, Y Kawabata, T Nitta, Y Saigo, Y Iwashita, S Suenaga, S Hamahira, H Indo, Yasuhiko Morita, H J. Majima and K Sugihara : Expression of permeability-glycoprotein(p-gp) and uptake of technetium-99m-hexakis-2-methoxy-isobutyl-isonitrile(99Tcm-MIBI)in malignant tumour of the head and neck, Dento Maxillo Facial Radiology, Vol.34, No.5, 274-278, 2005.

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