○種別 (必須): | □ | 学術論文 (審査論文)
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○言語 (必須): | □ | 英語
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○招待 (推奨): |
○審査 (推奨): | □ | Peer Review
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○カテゴリ (推奨): | □ | 研究
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○共著種別 (推奨): |
○学究種別 (推奨): |
○組織 (推奨): | 1. | 徳島大学.大学院ヘルスバイオサイエンス研究部.学長裁量プロジェクト (2004年6月1日〜2015年3月31日)
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○著者 (必須): | 1. | (英) Takeoka, Aya (日) (読)
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| 2. | (英) Shimizu, Miyuki (日) (読)
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| 3. | 堀尾 哲也
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○題名 (必須): | □ | (英) Identification of an α-tubulin mutant of fission yeast from γ-tubulin-interacting protein screening: genetic evidence for α-/ γ-tubulin interaction. (日)
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○副題 (任意): |
○要約 (任意): | □ | (英) gamma-Tubulin has been determined to be a central element of microtubule nucleation and, thus, indispensable for cellular organization of the microtubule. Utilizing the fact that human gamma-tubulin can function in the fission yeast Schizosaccharomyces pombe, we have generated a unique mutant screening procedure which can specifically select mutants of genes encoding gamma-tubulin-interacting proteins. One of the isolated mutants, cs76, turned out to carry a mutation in the alpha 1-tubulin gene (nda2(+)). This result suggests a direct interaction between the alpha- and gamma-tubulins. We located the mutation site in the nda2 gene and characterized the mutant phenotype. Our results demonstrate the importance of the alpha-/gamma-tubulin interaction in microtubule nucleation and should complement previous knowledge. (日)
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○キーワード (推奨): | 1. | (英) gamma-tubulin (日) ガンマチューブリン (読) がんまちゅーぶりん
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| 2. | (英) microtubule (日) 微小管 (読) びしょうかん
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○発行所 (推奨): | □ | The Company of Biologists Limited
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○誌名 (必須): | □ | Journal of Cell Science ([The Company of Biologists Limited])
(pISSN: 0021-9533, eISSN: 1477-9137)
○ISSN (任意): | □ | 0021-9533
ISSN: 0021-9533
(pISSN: 0021-9533, eISSN: 1477-9137) Title: Journal of cell scienceTitle(ISO): J Cell SciPublisher: Company of Biologists (NLM Catalog)
(Scopus)
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(Scopus information is found. [need login])
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○巻 (必須): | □ | 113
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○号 (必須): |
○頁 (必須): | □ | 4557 4562
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○年月日 (必須): | □ | 西暦 2000年 12月 初日 (平成 12年 12月 初日)
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○PMID (任意): | □ | 11082048 (→Scopusで検索)
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○Scopus (任意): | □ | 2-s2.0-0034496377
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○評価値 (任意): |
○被引用数 (任意): | □ | 1
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○指導教員 (推奨): |
○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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